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Journal ArticleDOI

Risk of Surgery for Inflammatory Bowel Diseases Has Decreased Over Time: A Systematic Review and Meta-analysis of Population-Based Studies

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TLDR
The risk of intestinal surgery among patients with IBD has decreased over the past 6 decades, and the trend in risk of surgery over time was analyzed by meta-regression using mixed-effect models.
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This article is published in Gastroenterology.The article was published on 2013-11-01. It has received 623 citations till now. The article focuses on the topics: Inflammatory bowel disease & Population.

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Detection and management of early stage inflammatory bowel disease: an update for clinicians

TL;DR: This work reviews the literature about the effectiveness of early detection and intervention in adult inflammatory bowel diseases patients and suggests that early therapeutic intervention with complete disease control may allow dose reduction or even treatment withdrawal in the maintenance phase, reducing side effects, costs, and also improving quality of life.
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Impact of Biological Agents on Postsurgical Complications in Inflammatory Bowel Disease: A Multicentre Study of Geteccu.

María José García, +63 more
TL;DR: In this paper, the authors evaluated the impact of preoperative administration of biologics on the risk of postoperative complications in inflammatory bowel disease (IBD) in 37 centres.
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Patient Outcomes Following Emergency Bowel Resection for Inflammatory Bowel Disease and the Impact of Surgical Subspecialisation in the North of England: A Retrospective Cohort Study

TL;DR: In this article, the authors evaluated the demographics and outcomes of patients with inflammatory bowel disease undergoing bowel resection and assessed for the potential impact of surgical subspecialisation on surgical outcomes.
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Preoperative factors associated with prolonged postoperative in-hospital length of stay in patients with Crohn's disease undergoing intestinal resection or strictureplasty.

TL;DR: Age, preoperative intra-abdominal abscess, and previous laparotomy/laparoscopy significantly prolonged LOS, which correlated with postoperative complications and can therefore be used in epidemiological or register-based studies as a surrogate for postoperative outcome.
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R: A language and environment for statistical computing.

R Core Team
- 01 Jan 2014 - 
TL;DR: Copyright (©) 1999–2012 R Foundation for Statistical Computing; permission is granted to make and distribute verbatim copies of this manual provided the copyright notice and permission notice are preserved on all copies.
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Measuring inconsistency in meta-analyses

TL;DR: A new quantity is developed, I 2, which the authors believe gives a better measure of the consistency between trials in a meta-analysis, which is susceptible to the number of trials included in the meta- analysis.
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Quantifying heterogeneity in a meta‐analysis

TL;DR: It is concluded that H and I2, which can usually be calculated for published meta-analyses, are particularly useful summaries of the impact of heterogeneity, and one or both should be presented in publishedMeta-an analyses in preference to the test for heterogeneity.
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Meta-analysis of observational studies in epidemiology - A proposal for reporting

TL;DR: A checklist contains specifications for reporting of meta-analyses of observational studies in epidemiology, including background, search strategy, methods, results, discussion, and conclusion should improve the usefulness ofMeta-an analyses for authors, reviewers, editors, readers, and decision makers.
Journal ArticleDOI

Operating characteristics of a rank correlation test for publication bias.

TL;DR: In this paper, an adjusted rank correlation test is proposed as a technique for identifying publication bias in a meta-analysis, and its operating characteristics are evaluated via simulations, and the test statistic is a direct statistical analogue of the popular funnel-graph.
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