Journal ArticleDOI
Risk of Surgery for Inflammatory Bowel Diseases Has Decreased Over Time: A Systematic Review and Meta-analysis of Population-Based Studies
Alexandra D. Frolkis,Jonathan Dykeman,Maria Negron,Jennifer deBruyn,Nathalie Jette,Kirsten M. Fiest,Talia Frolkis,Herman W. Barkema,Kevin P. Rioux,Remo Panaccione,Subrata Ghosh,Samuel Wiebe,Gilaad G. Kaplan +12 more
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TLDR
The risk of intestinal surgery among patients with IBD has decreased over the past 6 decades, and the trend in risk of surgery over time was analyzed by meta-regression using mixed-effect models.About:
This article is published in Gastroenterology.The article was published on 2013-11-01. It has received 623 citations till now. The article focuses on the topics: Inflammatory bowel disease & Population.read more
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Endospore forming bacteria may be associated with maintenance of surgically-induced remission in Crohn's disease.
Michael Laffin,Troy Perry,Heekuk Park,Patrick M. Gillevet,Masoumeh Sikaroodi,Gilaad G. Kaplan,Richard N. Fedorak,Karen I. Kroeker,Levinus A. Dieleman,Bryan Dicken,Karen L. Madsen +10 more
TL;DR: Analysis of mucosal biopsies taken at the time of ICR showed that decreased Clostridiales together with increased Enterobacteriales predicted disease recurrence, and an increase in the endospore-forming Lachnospiraceae from surgery to 6 months post-ICR was associated with remission.
Journal ArticleDOI
Paradigm Shift of Healthcare Cost for Patients with Inflammatory Bowel Diseases: A Claims Data-Based Analysis in Japan
TL;DR: Optimized use of anti-TNFα agents and introduction of biosimilars for anti-tumor necrosis factor-α agents can be expected to substantially reduce the health care costs of IBD.
Journal ArticleDOI
Factors Associated with Short-Term Morbidity in Patients Undergoing Colon Resection for Crohn's Disease.
TL;DR: Approximately one third of the patients who undergo colon resection for Crohn’s disease experience postoperative complications, and laparoscopic technique appears to be the preferred surgical treatment option for resection when feasible.
Journal ArticleDOI
Gut Serpinome: Emerging Evidence in IBD.
Héla Mkaouar,Vincent Mariaule,Soufien Rhimi,Juan Hernandez,Aicha Kriaa,Amin Jablaoui,Nizar Akermi,Emmanuelle Maguin,Adam Lesner,Brice Korkmaz,Moez Rhimi +10 more
TL;DR: In this paper, the role of serine protease inhibitors (serpins) encoded by the host are well reported; in contrast, those from the gut microbiota remain poorly studied.
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Test Characteristics of Cross-sectional Imaging and Concordance With Endoscopy in Postoperative Crohn’s Disease
TL;DR: In this paper , the concordance of cross-sectional imaging with endoscopic recurrence and the predictive ability of radiography for future CD post-operative recurrence was evaluated and a majority (54.2%) exhibited concordances (34.7% E+/R+; 19.4% E-/R-) between studies.
References
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R: A language and environment for statistical computing.
TL;DR: Copyright (©) 1999–2012 R Foundation for Statistical Computing; permission is granted to make and distribute verbatim copies of this manual provided the copyright notice and permission notice are preserved on all copies.
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Measuring inconsistency in meta-analyses
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Quantifying heterogeneity in a meta‐analysis
TL;DR: It is concluded that H and I2, which can usually be calculated for published meta-analyses, are particularly useful summaries of the impact of heterogeneity, and one or both should be presented in publishedMeta-an analyses in preference to the test for heterogeneity.
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Meta-analysis of observational studies in epidemiology - A proposal for reporting
Donna F. Stroup,Jesse A. Berlin,Sally C. Morton,Ingram Olkin,G. D. Williamson,Drummond Rennie,Drummond Rennie,David Moher,Betsy Jane Becker,Theresa Ann Sipe,Stephen B. Thacker +10 more
TL;DR: A checklist contains specifications for reporting of meta-analyses of observational studies in epidemiology, including background, search strategy, methods, results, discussion, and conclusion should improve the usefulness ofMeta-an analyses for authors, reviewers, editors, readers, and decision makers.
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Operating characteristics of a rank correlation test for publication bias.
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Toward an Integrated Clinical, Molecular and Serological Classification of Inflammatory Bowel Disease: Report of a Working Party of the 2005 Montreal World Congress of Gastroenterology
Mark S. Silverberg,Jack Satsangi,Tariq Ahmad,Ian D. Arnott,Charles N. Bernstein,Steven R. Brant,Renzo Caprilli,Jean-Frederic Colombel,Christoph Gasche,Karel Geboes,Derek P. Jewell,Amir Karban,Edward V. Loftus,A. Salvador Peña,Robert H. Riddell,David B. Sachar,Stefan Schreiber,A. Hillary Steinhart,Stephan R. Targan,Severine Vermeire,Bryan F. Warren +20 more