Journal ArticleDOI
Risk of Surgery for Inflammatory Bowel Diseases Has Decreased Over Time: A Systematic Review and Meta-analysis of Population-Based Studies
Alexandra D. Frolkis,Jonathan Dykeman,Maria Negron,Jennifer deBruyn,Nathalie Jette,Kirsten M. Fiest,Talia Frolkis,Herman W. Barkema,Kevin P. Rioux,Remo Panaccione,Subrata Ghosh,Samuel Wiebe,Gilaad G. Kaplan +12 more
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TLDR
The risk of intestinal surgery among patients with IBD has decreased over the past 6 decades, and the trend in risk of surgery over time was analyzed by meta-regression using mixed-effect models.About:
This article is published in Gastroenterology.The article was published on 2013-11-01. It has received 623 citations till now. The article focuses on the topics: Inflammatory bowel disease & Population.read more
Citations
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Crohn's disease associated strictures.
TL;DR: This review will evaluate the literature on the mechanism of intestinal fibrosis, emerging imaging techniques, and management strategies for CD associated strictures, and a promising first‐line alternative to surgery as it is less invasive and could preserve intestinal length.
Journal ArticleDOI
Culturing human intestinal stem cells for regenerative applications in the treatment of inflammatory bowel disease.
Fredrik Eo Holmberg,Jakob Benedict Seidelin,Xiaolei Yin,Benjamin E. Mead,Zhixiang Tong,Yuan Li,Jeffrey M. Karp,Ole Haagen Nielsen +7 more
TL;DR: In this article, a review of medium compositions and support matrices for optimal intestinal stem cell culture, as well as potential modifications to advance clinical use in inflammatory bowel disease (IBD) is presented.
Journal ArticleDOI
Role of MIF and D-DT in immune-inflammatory, autoimmune, and chronic respiratory diseases: from pathogenic factors to therapeutic targets
Sven Günther,Paolo Fagone,Gaël Jalce,Atanas G. Atanasov,Christophe Guignabert,Ferdinando Nicoletti +5 more
TL;DR: The role of MIF and D-DT in human immune-inflammatory, autoimmune, and chronic respiratory diseases is focused on, providing an update on the progress made in the identification of specific small-molecule inhibitors of these proteins.
Journal ArticleDOI
The Impact of Inflammatory Bowel Disease in Canada 2018: Direct Costs and Health Services Utilization.
M Ellen Kuenzig,Eric I Benchimol,Lawrence Lee,Laura E. Targownik,Harminder Singh,Gilaad G. Kaplan,Charles N. Bernstein,Alain Bitton,Geoffrey C. Nguyen,Kate Lee,Jane Cooke-Lauder,Sanjay K. Murthy +11 more
TL;DR: Direct health care costs of illness reflect the costs of medically necessary services and treatments paid for by public and private payers, including hospital-based care, outpatient physician consultations, prescription medications, diagnostic testing, complex continuing care, and home care.
Journal ArticleDOI
The management of patients with enteric hyperoxaluria.
TL;DR: Enteric hyperoxaluria is a common occurrence in the setting of fat malabsorption, usually due to intestinal resection or intestinal bypass surgery, and patients are at increased risk of urolithiasis and loss of kidney function from oxalate nephropathy.
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R: A language and environment for statistical computing.
TL;DR: Copyright (©) 1999–2012 R Foundation for Statistical Computing; permission is granted to make and distribute verbatim copies of this manual provided the copyright notice and permission notice are preserved on all copies.
Journal ArticleDOI
Measuring inconsistency in meta-analyses
TL;DR: A new quantity is developed, I 2, which the authors believe gives a better measure of the consistency between trials in a meta-analysis, which is susceptible to the number of trials included in the meta- analysis.
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Quantifying heterogeneity in a meta‐analysis
TL;DR: It is concluded that H and I2, which can usually be calculated for published meta-analyses, are particularly useful summaries of the impact of heterogeneity, and one or both should be presented in publishedMeta-an analyses in preference to the test for heterogeneity.
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Meta-analysis of observational studies in epidemiology - A proposal for reporting
Donna F. Stroup,Jesse A. Berlin,Sally C. Morton,Ingram Olkin,G. D. Williamson,Drummond Rennie,Drummond Rennie,David Moher,Betsy Jane Becker,Theresa Ann Sipe,Stephen B. Thacker +10 more
TL;DR: A checklist contains specifications for reporting of meta-analyses of observational studies in epidemiology, including background, search strategy, methods, results, discussion, and conclusion should improve the usefulness ofMeta-an analyses for authors, reviewers, editors, readers, and decision makers.
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Operating characteristics of a rank correlation test for publication bias.
TL;DR: In this paper, an adjusted rank correlation test is proposed as a technique for identifying publication bias in a meta-analysis, and its operating characteristics are evaluated via simulations, and the test statistic is a direct statistical analogue of the popular funnel-graph.
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Toward an Integrated Clinical, Molecular and Serological Classification of Inflammatory Bowel Disease: Report of a Working Party of the 2005 Montreal World Congress of Gastroenterology
Mark S. Silverberg,Jack Satsangi,Tariq Ahmad,Ian D. Arnott,Charles N. Bernstein,Steven R. Brant,Renzo Caprilli,Jean-Frederic Colombel,Christoph Gasche,Karel Geboes,Derek P. Jewell,Amir Karban,Edward V. Loftus,A. Salvador Peña,Robert H. Riddell,David B. Sachar,Stefan Schreiber,A. Hillary Steinhart,Stephan R. Targan,Severine Vermeire,Bryan F. Warren +20 more