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Journal ArticleDOI

Risk of Surgery for Inflammatory Bowel Diseases Has Decreased Over Time: A Systematic Review and Meta-analysis of Population-Based Studies

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TLDR
The risk of intestinal surgery among patients with IBD has decreased over the past 6 decades, and the trend in risk of surgery over time was analyzed by meta-regression using mixed-effect models.
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This article is published in Gastroenterology.The article was published on 2013-11-01. It has received 623 citations till now. The article focuses on the topics: Inflammatory bowel disease & Population.

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Citations
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Journal ArticleDOI

The global burden of IBD: from 2015 to 2025

TL;DR: The goal of this article is to establish the current epidemiology of IBD in the Western world, contrast it with the increase in IBD on health-care systems in newly industrialized countries and forecast the global effects of I BD in 2025.
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Selecting Therapeutic Targets in Inflammatory Bowel Disease (STRIDE): Determining Therapeutic Goals for Treat-to-Target.

TL;DR: Evidence- and consensus-based recommendations for selecting the goals for treat-to-target strategies in patients with IBD are made available and future studies are needed to determine how these targets will change disease course and patients’ quality of life.
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British Society of Gastroenterology consensus guidelines on the management of inflammatory bowel disease in adults

Christopher A. Lamb, +41 more
- 27 Sep 2019 - 
TL;DR: Comprehensive up-to-date guidance is provided regarding indications for, initiation and monitoring of immunosuppressive therapies, nutrition interventions, pre-, peri- and postoperative management, as well as structure and function of the multidisciplinary team and integration between primary and secondary care.
Journal ArticleDOI

ACG Clinical Guideline: Management of Crohn’s Disease in Adults

TL;DR: This guideline is intended to be flexible, not necessarily indicating the only acceptable approach, and should be distinguished from standards of care that are inflexible and rarely violated.
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ECCO Guidelines on Therapeutics in Crohn's Disease: Surgical Treatment

Joana Torres, +46 more
TL;DR: The present article addresses surgical management, including preoperative aspects and drug management before surgery, and provides technical advice for a variety of common clinical situations.
References
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Journal ArticleDOI

Risk factors for surgery and postoperative recurrence in Crohn's disease.

TL;DR: The frequency of surgery has decreased over time, but the postoperative relapse rate remains unchanged; three of four patients with CD will undergo an intestinal resection; half of them will ultimately relapse.
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Statistical heterogeneity in systematic reviews of clinical trials: a critical appraisal of guidelines and practice.

TL;DR: Recommendations that address practical issues are required to reduce the risk of spurious findings from investigations of heterogeneity, rather than simply adopting a cautious approach to their interpretation, unless a large number of studies is available.
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Infliximab maintenance treatment reduces hospitalizations, surgeries, and procedures in fistulizing Crohn’s disease

TL;DR: In patients with fistulizing Crohn's disease, infliximab 5 mg/kg every 8 weeks significantly reduced hospitalizations, surgeries, and procedures compared with placebo.
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Natural History of Pediatric Crohn's Disease: A Population-Based Cohort Study

TL;DR: Pediatric Crohn's disease was characterized by frequent occurrence, with time, of a severe phenotype with extensive, complicated disease and immunosuppressive therapy may improve the natural history of this disease and decrease the need for performing surgery.
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Increasing incidences of inflammatory bowel disease and decreasing surgery rates in Copenhagen City and County, 2003-2005: a population-based study from the Danish Crohn colitis database

TL;DR: The incidence of IBD in Copenhagen increased noticeably during the last decades, time from onset of symptoms until diagnosis decreased markedly, extent of CD was related to age at diagnosis, and the risk of surgery was low in UC.
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