Journal ArticleDOI
Risk of Surgery for Inflammatory Bowel Diseases Has Decreased Over Time: A Systematic Review and Meta-analysis of Population-Based Studies
Alexandra D. Frolkis,Jonathan Dykeman,Maria Negron,Jennifer deBruyn,Nathalie Jette,Kirsten M. Fiest,Talia Frolkis,Herman W. Barkema,Kevin P. Rioux,Remo Panaccione,Subrata Ghosh,Samuel Wiebe,Gilaad G. Kaplan +12 more
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TLDR
The risk of intestinal surgery among patients with IBD has decreased over the past 6 decades, and the trend in risk of surgery over time was analyzed by meta-regression using mixed-effect models.About:
This article is published in Gastroenterology.The article was published on 2013-11-01. It has received 623 citations till now. The article focuses on the topics: Inflammatory bowel disease & Population.read more
Citations
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Inflammatory bowel disease cause-specific mortality: a primer for clinicians.
Zain Kassam,Sara Belga,Idan Roifman,Simon A. Hirota,Humberto Jijon,Gilaad G. Kaplan,Subrata Ghosh,Paul L. Beck +7 more
TL;DR: Clinicians should be aware that conventional causes of death such as malignancy do not seem to be as significant a burden as originally perceived, however, emerging threats such as infection including C. difficile are noteworthy.
Journal ArticleDOI
Therapeutic drug monitoring of vedolizumab in inflammatory bowel disease: current data and future directions:
TL;DR: The introduction of vedolizumab, a lymphocyte adhesion inhibitor, has expanded the relatively limited therapeutic armamentarium available for Crohn’s disease and ulcerative colitis and how drug levels, immunogenicity and other factors influence clinical outcomes is summarized.
Journal ArticleDOI
Real-Time Shear Wave Ultrasound Elastography Differentiates Fibrotic from Inflammatory Strictures in Patients with Crohn’s Disease
Yujun Chen,Ren Mao,Xuehua Li,Qinghua Cao,Zhihui Chen,Baoxian Liu,Shuling Chen,Baili Chen,Yao He,Zhirong Zeng,Shomron Ben-Horin,Shomron Ben-Horin,Jordi Rimola,Florian Rieder,Xiaoyan Xie,Minhu Chen +15 more
TL;DR: This pilot study suggests that shear-wave elastography is feasible and accurate in detecting intestinal fibrosis in patients with CD and proposes a bowel ultrasound classification of intestinal strictures.
Journal ArticleDOI
Long-term outcomes of pediatric inflammatory bowel disease
TL;DR: Current knowledge and literature surrounding long-term outcomes of pediatric IBD are summarized, with emphasis on the following areas: need for surgery due to complicated disease behavior, risk of disease remission and recurrence, mental health and psychosocial well-being, educational outcomes, linear growth impairment, cancer risk, and mortality.
Culturing human intestinal stem cells for regenerative applications in the treatment of inflammatory bowel disease
Fredrik Eo Holmberg,Jakob Benedict Seidelin,Zhixiang Tong,Yuan Li,Ole Haagen Nielsen,Xiaolei Yin,Benjamin E. Mead,Jeffrey M. Karp +7 more
TL;DR: The aim of this review was to discuss medium compositions and support matrices for optimal intestinal stem cell culture, as well as potential modifications to advance clinical use in IBD.
References
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R: A language and environment for statistical computing.
TL;DR: Copyright (©) 1999–2012 R Foundation for Statistical Computing; permission is granted to make and distribute verbatim copies of this manual provided the copyright notice and permission notice are preserved on all copies.
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Measuring inconsistency in meta-analyses
TL;DR: A new quantity is developed, I 2, which the authors believe gives a better measure of the consistency between trials in a meta-analysis, which is susceptible to the number of trials included in the meta- analysis.
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Quantifying heterogeneity in a meta‐analysis
TL;DR: It is concluded that H and I2, which can usually be calculated for published meta-analyses, are particularly useful summaries of the impact of heterogeneity, and one or both should be presented in publishedMeta-an analyses in preference to the test for heterogeneity.
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Meta-analysis of observational studies in epidemiology - A proposal for reporting
Donna F. Stroup,Jesse A. Berlin,Sally C. Morton,Ingram Olkin,G. D. Williamson,Drummond Rennie,Drummond Rennie,David Moher,Betsy Jane Becker,Theresa Ann Sipe,Stephen B. Thacker +10 more
TL;DR: A checklist contains specifications for reporting of meta-analyses of observational studies in epidemiology, including background, search strategy, methods, results, discussion, and conclusion should improve the usefulness ofMeta-an analyses for authors, reviewers, editors, readers, and decision makers.
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Operating characteristics of a rank correlation test for publication bias.
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Related Papers (5)
Toward an Integrated Clinical, Molecular and Serological Classification of Inflammatory Bowel Disease: Report of a Working Party of the 2005 Montreal World Congress of Gastroenterology
Mark S. Silverberg,Jack Satsangi,Tariq Ahmad,Ian D. Arnott,Charles N. Bernstein,Steven R. Brant,Renzo Caprilli,Jean-Frederic Colombel,Christoph Gasche,Karel Geboes,Derek P. Jewell,Amir Karban,Edward V. Loftus,A. Salvador Peña,Robert H. Riddell,David B. Sachar,Stefan Schreiber,A. Hillary Steinhart,Stephan R. Targan,Severine Vermeire,Bryan F. Warren +20 more