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Journal ArticleDOI

Risk of Surgery for Inflammatory Bowel Diseases Has Decreased Over Time: A Systematic Review and Meta-analysis of Population-Based Studies

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TLDR
The risk of intestinal surgery among patients with IBD has decreased over the past 6 decades, and the trend in risk of surgery over time was analyzed by meta-regression using mixed-effect models.
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This article is published in Gastroenterology.The article was published on 2013-11-01. It has received 623 citations till now. The article focuses on the topics: Inflammatory bowel disease & Population.

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Citations
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Journal ArticleDOI

The global burden of IBD: from 2015 to 2025

TL;DR: The goal of this article is to establish the current epidemiology of IBD in the Western world, contrast it with the increase in IBD on health-care systems in newly industrialized countries and forecast the global effects of I BD in 2025.
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Selecting Therapeutic Targets in Inflammatory Bowel Disease (STRIDE): Determining Therapeutic Goals for Treat-to-Target.

TL;DR: Evidence- and consensus-based recommendations for selecting the goals for treat-to-target strategies in patients with IBD are made available and future studies are needed to determine how these targets will change disease course and patients’ quality of life.
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British Society of Gastroenterology consensus guidelines on the management of inflammatory bowel disease in adults

Christopher A. Lamb, +41 more
- 27 Sep 2019 - 
TL;DR: Comprehensive up-to-date guidance is provided regarding indications for, initiation and monitoring of immunosuppressive therapies, nutrition interventions, pre-, peri- and postoperative management, as well as structure and function of the multidisciplinary team and integration between primary and secondary care.
Journal ArticleDOI

ACG Clinical Guideline: Management of Crohn’s Disease in Adults

TL;DR: This guideline is intended to be flexible, not necessarily indicating the only acceptable approach, and should be distinguished from standards of care that are inflexible and rarely violated.
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ECCO Guidelines on Therapeutics in Crohn's Disease: Surgical Treatment

Joana Torres, +46 more
TL;DR: The present article addresses surgical management, including preoperative aspects and drug management before surgery, and provides technical advice for a variety of common clinical situations.
References
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Journal ArticleDOI

Mucosal Healing in Inflammatory Bowel Disease: Results From a Norwegian Population-Based Cohort

TL;DR: The present results give further strength to the use of mucosal healing as a clinical indicator and treatment goal in inflammatory bowel disease.
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Azathioprine and 6-Mercaptopurine in Crohn Disease: A Meta-Analysis

TL;DR: Azathioprine and 6-mercaptopurine are effective in treating active Crohn disease and in maintaining remission of quiescent disease as mentioned in this paper, however, adverse effects were more common among patients receiving therapy.
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Clinical course during the first 10 years of ulcerative colitis: results from a population-based inception cohort (IBSEN Study)

TL;DR: The prognosis for UC during the first 10 years was generally good, the colectomy rate was low, and a large proportion of patients were in remission as time progressed, suggesting patients with initially extensive colitis and elevated ESR could benefit from an early potent medical treatment strategy.
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Clinical course in Crohn's disease: results of a Norwegian population-based ten-year follow-up study.

TL;DR: The prognosis for CD seems better than previously reported, the probability of surgery was low, and fewer than expected developed complicated disease behavior, and the finding of prognostic risk factors for subsequent surgery might call for attention to early effective medical treatment strategies.
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Direct health care costs of Crohn's disease and ulcerative colitis in US children and adults.

TL;DR: This study demonstrates a substantial economic burden of IBD and can be used to inform health policy as well as identify sociodemographic factors influencing these costs.
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