Journal ArticleDOI
Risk of Surgery for Inflammatory Bowel Diseases Has Decreased Over Time: A Systematic Review and Meta-analysis of Population-Based Studies
Alexandra D. Frolkis,Jonathan Dykeman,Maria Negron,Jennifer deBruyn,Nathalie Jette,Kirsten M. Fiest,Talia Frolkis,Herman W. Barkema,Kevin P. Rioux,Remo Panaccione,Subrata Ghosh,Samuel Wiebe,Gilaad G. Kaplan +12 more
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TLDR
The risk of intestinal surgery among patients with IBD has decreased over the past 6 decades, and the trend in risk of surgery over time was analyzed by meta-regression using mixed-effect models.About:
This article is published in Gastroenterology.The article was published on 2013-11-01. It has received 623 citations till now. The article focuses on the topics: Inflammatory bowel disease & Population.read more
Citations
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Contemporary Management of Ulcerative Colitis
Rohini Vanga,Millie D. Long +1 more
TL;DR: The newest evidence-based data on management of ulcerative colitis discusses risk-stratification, optimizing medical therapies, and surgical outcomes of UC, and finds the superiority of combination therapy with azathioprine over monotherapy with infliximab or azATHioprine alone.
Journal ArticleDOI
Public versus Private Drug Insurance and Outcomes of Patients Requiring Biologic Therapies for Inflammatory Bowel Disease.
Amir Rumman,Roberto Candia,Justina J. Sam,Kenneth Croitoru,Mark S. Silverberg,A. Hillary Steinhart,Geoffrey C. Nguyen +6 more
TL;DR: IBD patients in Ontario with public drug coverage experienced greater delays in access to anti-TNF therapy than privately insured patients and have a higher rate of hospitalizations and ED visits related to IBD.
Journal ArticleDOI
The risk of disabling, surgery and reoperation in Crohn's disease - A decision tree-based approach to prognosis.
Cláudia Camila Dias,Pedro Pereira Rodrigues,Samuel Fernandes,Francisco Portela,Paula Ministro,Diana Martins,Paula Sousa,Paula Lago,Isadora Rosa,Luis M. Correia,Paula Moura Santos,Fernando Magro +11 more
TL;DR: The decision-tree based approach used in this study, with demographic and clinical variables, has shown to be a valid and useful approach to depict such risks of disabling, surgery and reoperation.
Journal ArticleDOI
The impact of biologics in surgical outcomes in ulcerative colitis
TL;DR: The aim of this review is to describe all relevant data available and briefly summarize the real impact of biologics in surgical outcomes in ulcerative colitis.
Journal ArticleDOI
Clinical Predictors of the Risk of Early Colectomy in Ulcerative Colitis: A Population-based Study.
Ahmed Al-Darmaki,James Hubbard,Cynthia H. Seow,Yvette Leung,Kerri L. Novak,Abdel Aziz M. Shaheen,Remo Panaccione,Gilaad G. Kaplan +7 more
TL;DR: Patients admitted to hospital with UC within 3 years of diagnosis have a high risk of early colectomy, particularly true in middle-aged men, those living in rural areas, and those without response to infliximab.
References
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R: A language and environment for statistical computing.
TL;DR: Copyright (©) 1999–2012 R Foundation for Statistical Computing; permission is granted to make and distribute verbatim copies of this manual provided the copyright notice and permission notice are preserved on all copies.
Journal ArticleDOI
Measuring inconsistency in meta-analyses
TL;DR: A new quantity is developed, I 2, which the authors believe gives a better measure of the consistency between trials in a meta-analysis, which is susceptible to the number of trials included in the meta- analysis.
Journal ArticleDOI
Quantifying heterogeneity in a meta‐analysis
TL;DR: It is concluded that H and I2, which can usually be calculated for published meta-analyses, are particularly useful summaries of the impact of heterogeneity, and one or both should be presented in publishedMeta-an analyses in preference to the test for heterogeneity.
Journal ArticleDOI
Meta-analysis of observational studies in epidemiology - A proposal for reporting
Donna F. Stroup,Jesse A. Berlin,Sally C. Morton,Ingram Olkin,G. D. Williamson,Drummond Rennie,Drummond Rennie,David Moher,Betsy Jane Becker,Theresa Ann Sipe,Stephen B. Thacker +10 more
TL;DR: A checklist contains specifications for reporting of meta-analyses of observational studies in epidemiology, including background, search strategy, methods, results, discussion, and conclusion should improve the usefulness ofMeta-an analyses for authors, reviewers, editors, readers, and decision makers.
Journal ArticleDOI
Operating characteristics of a rank correlation test for publication bias.
TL;DR: In this paper, an adjusted rank correlation test is proposed as a technique for identifying publication bias in a meta-analysis, and its operating characteristics are evaluated via simulations, and the test statistic is a direct statistical analogue of the popular funnel-graph.
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Toward an Integrated Clinical, Molecular and Serological Classification of Inflammatory Bowel Disease: Report of a Working Party of the 2005 Montreal World Congress of Gastroenterology
Mark S. Silverberg,Jack Satsangi,Tariq Ahmad,Ian D. Arnott,Charles N. Bernstein,Steven R. Brant,Renzo Caprilli,Jean-Frederic Colombel,Christoph Gasche,Karel Geboes,Derek P. Jewell,Amir Karban,Edward V. Loftus,A. Salvador Peña,Robert H. Riddell,David B. Sachar,Stefan Schreiber,A. Hillary Steinhart,Stephan R. Targan,Severine Vermeire,Bryan F. Warren +20 more