Journal ArticleDOI
Risk of Surgery for Inflammatory Bowel Diseases Has Decreased Over Time: A Systematic Review and Meta-analysis of Population-Based Studies
Alexandra D. Frolkis,Jonathan Dykeman,Maria Negron,Jennifer deBruyn,Nathalie Jette,Kirsten M. Fiest,Talia Frolkis,Herman W. Barkema,Kevin P. Rioux,Remo Panaccione,Subrata Ghosh,Samuel Wiebe,Gilaad G. Kaplan +12 more
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TLDR
The risk of intestinal surgery among patients with IBD has decreased over the past 6 decades, and the trend in risk of surgery over time was analyzed by meta-regression using mixed-effect models.About:
This article is published in Gastroenterology.The article was published on 2013-11-01. It has received 623 citations till now. The article focuses on the topics: Inflammatory bowel disease & Population.read more
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Real-world evidence of tofacitinib effectiveness and safety in patients with refractory ulcerative colitis
Loriane Lair-Mehiri,Carmen Stefanescu,Thibaut Vaysse,David Laharie,Xavier Roblin,Isabelle Rosa,Xavier Treton,Vered Abitbol,Aurelien Amiot,Guillaume Bouguen,Nina Dib,Mathurin Fumery,Benjamin Pariente,Franck Carbonnel,Laurent Peyrin-Biroulet,Marion Simon,Stephanie Viennot,Yoram Bouhnik +17 more
TL;DR: In a highly refractory UC population, one third of patients treated with tofacitinib achieved steroid-free clinical remission at week 14 and 70% of patients avoided colectomy at one year, with an acceptable safety profile.
Journal ArticleDOI
Micronutrient Absorption and Related Outcomes in People with Inflammatory Bowel Disease: A Review.
TL;DR: Increased research and clinician knowledge of the relationship between micronutrients and IBD may manifest in improved nutrient screening, monitoring, treatment, and outcomes for people living with IBD.
Journal ArticleDOI
Capsular polysaccharide correlates with immune response to the human gut microbe Ruminococcus gnavus .
Matthew T. Henke,Eric M. Brown,Chelsi D. Cassilly,Hera Vlamakis,Hera Vlamakis,Ramnik J. Xavier,Ramnik J. Xavier,Jon Clardy +7 more
TL;DR: This paper showed that only some isolates of Ruminococcus gnavus produce a capsular polysaccharide that promotes a tolerogenic immune response, whereas isolates lacking functional capsule biosynthetic genes elicit robust proinflammatory responses in vitro.
Journal ArticleDOI
Trends in hospitalisation rates for inflammatory bowel disease in western versus newly industrialised countries: a population-based study of countries in the Organisation for Economic Co-operation and Development
James King,Fox E. Underwood,Nicola Panaccione,Josh Quan,Joseph W. Windsor,Paulo Gustavo Kotze,Siew C. Ng,Subrata Ghosh,Peter L. Lakatos,Peter L. Lakatos,T. Jess,Remo Panaccione,Cynthia H. Seow,Shomron Ben-Horin,Johan Burisch,Johan Burisch,Jean-Frederic Colombel,Edward V. Loftus,Richard B. Gearry,Jonas Halfvarson,Gilaad G. Kaplan +20 more
TL;DR: Hospitalisation rates for IBD are high in western countries but are typically stabilising or decreasing, whereas rates in many newly industrialised countries are rapidly increasing, which reflects the known increase in IBD prevalence in these countries.
Journal ArticleDOI
Factors associated with readmission to the hospital within 30 days in patients with inflammatory bowel disease.
Dejan Micic,John N. Gaetano,Jonah N. Rubin,Russell D. Cohen,Atsushi Sakuraba,David T. Rubin,Joel Pekow +6 more
TL;DR: Analysis of data from a US publicly available all-payer inpatient healthcare database identified patient and hospitalization risk factors associated with 30-day readmission and identified patients at high risk for readmission.
References
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TL;DR: Copyright (©) 1999–2012 R Foundation for Statistical Computing; permission is granted to make and distribute verbatim copies of this manual provided the copyright notice and permission notice are preserved on all copies.
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Meta-analysis of observational studies in epidemiology - A proposal for reporting
Donna F. Stroup,Jesse A. Berlin,Sally C. Morton,Ingram Olkin,G. D. Williamson,Drummond Rennie,Drummond Rennie,David Moher,Betsy Jane Becker,Theresa Ann Sipe,Stephen B. Thacker +10 more
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Toward an Integrated Clinical, Molecular and Serological Classification of Inflammatory Bowel Disease: Report of a Working Party of the 2005 Montreal World Congress of Gastroenterology
Mark S. Silverberg,Jack Satsangi,Tariq Ahmad,Ian D. Arnott,Charles N. Bernstein,Steven R. Brant,Renzo Caprilli,Jean-Frederic Colombel,Christoph Gasche,Karel Geboes,Derek P. Jewell,Amir Karban,Edward V. Loftus,A. Salvador Peña,Robert H. Riddell,David B. Sachar,Stefan Schreiber,A. Hillary Steinhart,Stephan R. Targan,Severine Vermeire,Bryan F. Warren +20 more