Journal ArticleDOI
Risk of Surgery for Inflammatory Bowel Diseases Has Decreased Over Time: A Systematic Review and Meta-analysis of Population-Based Studies
Alexandra D. Frolkis,Jonathan Dykeman,Maria Negron,Jennifer deBruyn,Nathalie Jette,Kirsten M. Fiest,Talia Frolkis,Herman W. Barkema,Kevin P. Rioux,Remo Panaccione,Subrata Ghosh,Samuel Wiebe,Gilaad G. Kaplan +12 more
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TLDR
The risk of intestinal surgery among patients with IBD has decreased over the past 6 decades, and the trend in risk of surgery over time was analyzed by meta-regression using mixed-effect models.About:
This article is published in Gastroenterology.The article was published on 2013-11-01. It has received 623 citations till now. The article focuses on the topics: Inflammatory bowel disease & Population.read more
Citations
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Down the line from genome-wide association studies in inflammatory bowel disease: the resulting clinical benefits and the outlook for the future
TL;DR: This review will discuss how the IBD genetic risk loci were identified and how this knowledge can be translated towards clinical practice.
Journal ArticleDOI
Men With Inflammatory Bowel Disease: Sexual Function, Fertility, Medication Safety, and Prostate Cancer.
TL;DR: Patients with IBD seem to be at a higher risk for prostate cancer; therefore, screening as recommended for high-risk patients should be considered.
Journal ArticleDOI
Trends in emergency department visits and hospitalization rates for inflammatory bowel disease in the era of biologics.
Gunn Huh,Hyuk Yoon,Yoon Jin Choi,Cheol Min Shin,Young Soo Park,Nayoung Kim,Nayoung Kim,Dong Ho Lee,Dong Ho Lee,Joo Sung Kim +9 more
TL;DR: The proportion of ED visits decreased from 2007 to 2014; there was no significant change in hospitalization rates.
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Joint Canadian Association of Gastroenterology and Crohn's Colitis Canada Position Statement on Biosimilars for the Treatment of Inflammatory Bowel Disease.
Paul Moayyedi,Eric I Benchimol,David Armstrong,Cathy Yuhong Yuan,Aida Fernandes,Grigorios I. Leontiadis +5 more
TL;DR: The emergence of biosimilars have provided an opportunity for third party payers to reduce anti-TNF therapy drug costs and, accounting for these societal costs, biologics may offer value for money.
Journal ArticleDOI
Risk of Major Abdominal Surgery in an Asian Population-based Crohn's Disease Cohort.
Anuradha Pandey,Ennaliza Salazar,Christopher S. C. Kong,Wee Chian Lim,Jeannie Ong,David E. Ong,Christina Ong,Marion M. Aw,Eric Wee,Sai Wei Chuah,Valerie Tan,Wei Lin Tay,Nivedita Nadkarni,Khoon Lin Ling +13 more
TL;DR: It is suggested that both environmental and genetic factors contribute to the risk of surgery in Asian patients with CD, and age at diagnosis, L1 location, B2, and B3 disease behavior are independent risk factors for abdominal surgery.
References
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R: A language and environment for statistical computing.
TL;DR: Copyright (©) 1999–2012 R Foundation for Statistical Computing; permission is granted to make and distribute verbatim copies of this manual provided the copyright notice and permission notice are preserved on all copies.
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Measuring inconsistency in meta-analyses
TL;DR: A new quantity is developed, I 2, which the authors believe gives a better measure of the consistency between trials in a meta-analysis, which is susceptible to the number of trials included in the meta- analysis.
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Quantifying heterogeneity in a meta‐analysis
TL;DR: It is concluded that H and I2, which can usually be calculated for published meta-analyses, are particularly useful summaries of the impact of heterogeneity, and one or both should be presented in publishedMeta-an analyses in preference to the test for heterogeneity.
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Meta-analysis of observational studies in epidemiology - A proposal for reporting
Donna F. Stroup,Jesse A. Berlin,Sally C. Morton,Ingram Olkin,G. D. Williamson,Drummond Rennie,Drummond Rennie,David Moher,Betsy Jane Becker,Theresa Ann Sipe,Stephen B. Thacker +10 more
TL;DR: A checklist contains specifications for reporting of meta-analyses of observational studies in epidemiology, including background, search strategy, methods, results, discussion, and conclusion should improve the usefulness ofMeta-an analyses for authors, reviewers, editors, readers, and decision makers.
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Operating characteristics of a rank correlation test for publication bias.
TL;DR: In this paper, an adjusted rank correlation test is proposed as a technique for identifying publication bias in a meta-analysis, and its operating characteristics are evaluated via simulations, and the test statistic is a direct statistical analogue of the popular funnel-graph.
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Toward an Integrated Clinical, Molecular and Serological Classification of Inflammatory Bowel Disease: Report of a Working Party of the 2005 Montreal World Congress of Gastroenterology
Mark S. Silverberg,Jack Satsangi,Tariq Ahmad,Ian D. Arnott,Charles N. Bernstein,Steven R. Brant,Renzo Caprilli,Jean-Frederic Colombel,Christoph Gasche,Karel Geboes,Derek P. Jewell,Amir Karban,Edward V. Loftus,A. Salvador Peña,Robert H. Riddell,David B. Sachar,Stefan Schreiber,A. Hillary Steinhart,Stephan R. Targan,Severine Vermeire,Bryan F. Warren +20 more