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Risk of Surgery for Inflammatory Bowel Diseases Has Decreased Over Time: A Systematic Review and Meta-analysis of Population-Based Studies

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TLDR
The risk of intestinal surgery among patients with IBD has decreased over the past 6 decades, and the trend in risk of surgery over time was analyzed by meta-regression using mixed-effect models.
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This article is published in Gastroenterology.The article was published on 2013-11-01. It has received 623 citations till now. The article focuses on the topics: Inflammatory bowel disease & Population.

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Peripheral Blood DNA Methylation Profiles Do Not Predict Endoscopic Post-Operative Recurrence in Crohn’s Disease Patients

TL;DR: It is concluded that PBL DNA methylation is not a feasible predictive tool in post-operative CD because of the limited differences in the genome-wide DNA methylome among CD patients with and without endoscopic POR.
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Effects of ethnicity and socioeconomic status on surgical outcomes from inflammatory bowel disease

TL;DR: Ethnic minority status and socioeconomic deprivation were associated with worse surgical outcomes within the authors' cohort of IBD patients, and these findings may stimulate discourse regarding the strategic planning of equitable healthcare services.
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R: A language and environment for statistical computing.

R Core Team
- 01 Jan 2014 - 
TL;DR: Copyright (©) 1999–2012 R Foundation for Statistical Computing; permission is granted to make and distribute verbatim copies of this manual provided the copyright notice and permission notice are preserved on all copies.
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Measuring inconsistency in meta-analyses

TL;DR: A new quantity is developed, I 2, which the authors believe gives a better measure of the consistency between trials in a meta-analysis, which is susceptible to the number of trials included in the meta- analysis.
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Quantifying heterogeneity in a meta‐analysis

TL;DR: It is concluded that H and I2, which can usually be calculated for published meta-analyses, are particularly useful summaries of the impact of heterogeneity, and one or both should be presented in publishedMeta-an analyses in preference to the test for heterogeneity.
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Meta-analysis of observational studies in epidemiology - A proposal for reporting

TL;DR: A checklist contains specifications for reporting of meta-analyses of observational studies in epidemiology, including background, search strategy, methods, results, discussion, and conclusion should improve the usefulness ofMeta-an analyses for authors, reviewers, editors, readers, and decision makers.
Journal ArticleDOI

Operating characteristics of a rank correlation test for publication bias.

TL;DR: In this paper, an adjusted rank correlation test is proposed as a technique for identifying publication bias in a meta-analysis, and its operating characteristics are evaluated via simulations, and the test statistic is a direct statistical analogue of the popular funnel-graph.
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