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Journal ArticleDOI

Risk of Surgery for Inflammatory Bowel Diseases Has Decreased Over Time: A Systematic Review and Meta-analysis of Population-Based Studies

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TLDR
The risk of intestinal surgery among patients with IBD has decreased over the past 6 decades, and the trend in risk of surgery over time was analyzed by meta-regression using mixed-effect models.
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This article is published in Gastroenterology.The article was published on 2013-11-01. It has received 623 citations till now. The article focuses on the topics: Inflammatory bowel disease & Population.

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Inflammatory markers may predict post‐operative complications and recurrence in Crohn's disease patients undergoing gastrointestinal surgery

TL;DR: Blood cell interaction based inflammatory markers have proven useful in predicting patient outcomes in oncological and benign diseases and their prognostic value in CD patients undergoing surgery was investigated.
Journal ArticleDOI

Preoperative Exclusive Total Parental Nutrition is Associated with Clinical and Laboratory Remission in Severe Active Crohn’s Disease—A Pilot Study

TL;DR: Exclusive preoperative TPN was found to provide significant improvement in nutritional status, and clinical and laboratory remission in severe active Crohn’s patients.
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Therapeutic preferences and outcomes in newly diagnosed patients with Crohn's diseases in the biological era in Hungary: A nationwide study based on the National Health Insurance Fund database

TL;DR: IS and biological exposure became more frequent, while hospitalization decreased and surgery remained low but constant during the observation period, suggesting that maximal treatment step can be regarded as proxy severity marker in patients with IBD.
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Rectal Cancer Incidence is Low Following Rectal Diversion or Subtotal Colectomy for IBD: Results of a Population-based Study.

TL;DR: In this paper, the authors performed a population-based retrospective cohort study in Ontario, Canada, of all patients undergoing either subtotal colectomy or diversion for medically refractory inflammatory bowel disease (IBD), and evaluated the effect of surveillance endoscopy on the rate of rectal cancer.
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Journal Article

R: A language and environment for statistical computing.

R Core Team
- 01 Jan 2014 - 
TL;DR: Copyright (©) 1999–2012 R Foundation for Statistical Computing; permission is granted to make and distribute verbatim copies of this manual provided the copyright notice and permission notice are preserved on all copies.
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Measuring inconsistency in meta-analyses

TL;DR: A new quantity is developed, I 2, which the authors believe gives a better measure of the consistency between trials in a meta-analysis, which is susceptible to the number of trials included in the meta- analysis.
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Quantifying heterogeneity in a meta‐analysis

TL;DR: It is concluded that H and I2, which can usually be calculated for published meta-analyses, are particularly useful summaries of the impact of heterogeneity, and one or both should be presented in publishedMeta-an analyses in preference to the test for heterogeneity.
Journal ArticleDOI

Meta-analysis of observational studies in epidemiology - A proposal for reporting

TL;DR: A checklist contains specifications for reporting of meta-analyses of observational studies in epidemiology, including background, search strategy, methods, results, discussion, and conclusion should improve the usefulness ofMeta-an analyses for authors, reviewers, editors, readers, and decision makers.
Journal ArticleDOI

Operating characteristics of a rank correlation test for publication bias.

TL;DR: In this paper, an adjusted rank correlation test is proposed as a technique for identifying publication bias in a meta-analysis, and its operating characteristics are evaluated via simulations, and the test statistic is a direct statistical analogue of the popular funnel-graph.
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