Journal ArticleDOI
Role of periodontal therapy in management of common complex systemic diseases and conditions: An update.
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The results suggest that nonsurgicalperiodontal intervention provided to pregnant women is safe and improves periodontal status without preventing adverse pregnancy outcomes.Abstract:
The goal of this review is to summarize the results of randomized trials reported since 2010 that assessed the effect of periodontal interventions on at least one systemic outcome in human subjects of any age, gender or ethnicity Oral outcome measures included gingivitis, pocket depth, clinical attachment loss and/or radiographic bone loss and oral hygiene indices Studies were excluded if the trial was not completed or if treatment was not randomized The results suggest that nonsurgical periodontal intervention provided to pregnant women is safe and improves periodontal status without preventing adverse pregnancy outcomes Nonsurgical periodontal intervention was also found to provide modest improvement in glycemic control in individuals with type 2 diabetes mellitus and periodontitis Also, improving oral care through mechanical or chemical control of dental-plaque biofilm formation can contribute to the prevention of respiratory infections in differing clinical settings, including hospitals and nursing homes, and in patients with chronic obstructive pulmonary disease No clinical trials were reported that tested the effect of periodontal interventions on medical outcomes of atherosclerosis, cardiovascular diseases, stroke, rheumatoid arthritis, Alzheimer's disease, chronic kidney disease or malignant neoplasiaread more
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Periodontitis and respiratory diseases: A systematic review with meta-analysis.
Isaac Suzart Gomes-Filho,Simone Seixas da Cruz,Soraya Castro Trindade,Johelle de Santana Passos-Soares,Johelle de Santana Passos-Soares,Paulo Cirino de Carvalho-Filho,Ana Claudia Morais Godoy Figueiredo,Amanda Oliveira Lyrio,Alexandre Marcelo Hintz,Maurício Gomes Pereira,Frank A. Scannapieco +10 more
TL;DR: An association between periodontitis and asthma, chronic obstructive pulmonary disease, COPD and pneumonia was validated and fixed and random effects meta-analysis were performed for the calculation of the association measurements.
Journal ArticleDOI
Vitamin D Deficiency and Oral Health: A Comprehensive Review.
TL;DR: This review aims to provide comprehensive evidence of how VD levels should be considered to promote good oral health, and to summarize how VDD may hamper oral development and its role in certain oral conditions.
Journal ArticleDOI
Lifestyle and periodontitis: The emergence of personalized periodontics.
TL;DR: This volume of Periodontology 2000 explores how new advances in the understanding of periodontitis within a medical model can evolve into new treatment strategies tailor-made for individual patients and not merely based on wholesale treatment paradigms.
Journal ArticleDOI
Apical Periodontitis Is Associated with Elevated Concentrations of Inflammatory Mediators in Peripheral Blood: A Systematic Review and Meta-analysis.
Athina Christina Georgiou,Wim Crielaard,Iakovos Armenis,Ralph de Vries,Suzette V. van der Waal +4 more
TL;DR: The existing literature indicates that AP adds on to systemic inflammation by elevating C-reactive protein, interleukin 6, asymmetric dimethylarginine, and C3 levels, and there is now stronger evidence that AP contributes to low-grade systemic inflammation.
Journal ArticleDOI
Periodontal disease and its impact on general health in Latin America. Section V: Treatment of periodontitis.
Ricardo Guimarães Fischer,Ronaldo Lira Junior,Belén Retamal-Valdes,Luciene Cristina Figueiredo,Zilson Malheiros,Bernal Stewart,Magda Feres +6 more
TL;DR: Non-surgical and surgical periodontal treatments are predictable procedures in terms of controlling infection, reducing probing pocket depth and gaining clinical attachment and the treatment of periodontitis may significantly improve OHRQoL and promote a reduction of systemic markers of inflammation.
References
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Williams,Emma Witt,Frederick Wolfe,Anthony D. Woolf,Sarah Wulf,Pon Hsiu Yeh,Anita K. M. Zaidi,Zhi Jie Zheng,David Zonies,Alan D. Lopez,Christopher J L Murray +363 more
TL;DR: Prevalence and severity of health loss were weakly correlated and age-specific prevalence of YLDs increased with age in all regions and has decreased slightly from 1990 to 2010, but population growth and ageing have increased YLD numbers and crude rates over the past two decades.
Journal ArticleDOI
Epidemiology and causes of preterm birth
TL;DR: A short cervical length and a raised cervical-vaginal fetal fibronectin concentration are the strongest predictors of spontaneous preterm birth.
Journal ArticleDOI
The Placenta Harbors a Unique Microbiome
TL;DR: A unique placental microbiome niche was characterized, composed of nonpathogenic commensal microbiota from the Firmicutes, Tenericute, Proteobacteria, Bacteroidetes, and Fusobacteria phyla, which was consistently different from those reported in other parts of the body, including the skin and urogenital tract.
Journal ArticleDOI
Global burden of oral conditions in 1990-2010: a systematic analysis
Wagner Marcenes,Nicholas J Kassebaum,Eduardo Bernabé,Abraham D. Flaxman,Mohsen Naghavi,Alan D. Lopez,Alan D. Lopez,Christopher J L Murray +7 more
TL;DR: The global burden of untreated caries, severe periodontitis, and severe tooth loss in 2010 is reported on and the challenge in responding to the diversity of urgent oral health needs worldwide is highlighted, particularly in developing communities.
Journal ArticleDOI
Defining the relationship between plasma glucose and HbA(1c): analysis of glucose profiles and HbA(1c) in the Diabetes Control and Complications Trial.
Curt L. Rohlfing,Hsiao-Mei Wiedmeyer,Randie R. Little,J D England,Alethea L. Tennill,David E. Goldstein +5 more
TL;DR: Knowing the relationship between HbA(1c) and plasma glucose (PG) levels in patients with type 1 diabetes can help patients with diabetes and their healthcare providers set day-to-day targets for PG to achieve specific HBA( 1c) goals.