Journal ArticleDOI
The 2001 Bethesda System: terminology for reporting results of cervical cytology.
Diane Solomon,Diane D. Davey,Robert J. Kurman,Marianne U. Prey,Stephen S. Raab,Mark E. Sherman,David C. Wilbur,Nancy A. Young +7 more
TLDR
The 2001 Bethesda System terminology reflects important advances in biological understanding of cervical neoplasia and cervical screening technology.Abstract:
ObjectivesThe Bethesda 2001 Workshop was convened to evaluate and update the 1991
Bethesda System terminology for reporting the results of cervical cytology.
A primary objective was to develop a new approach to broaden participation
in the consensus process.ParticipantsForum groups composed of 6 to 10 individuals were responsible for developing
recommendations for discussion at the workshop. Each forum group included
at least 1 cytopathologist, cytotechnologist, clinician, and international
representative to ensure a broad range of views and interests. More than 400
cytopathologists, cytotechnologists, histopathologists, family practitioners,
gynecologists, public health physicians, epidemiologists, patient advocates,
and attorneys participated in the workshop, which was convened by the National
Cancer Institute and cosponsored by 44 professional societies. More than 20
countries were represented.EvidenceLiterature review, expert opinion, and input from an Internet bulletin
board were all considered in developing recommendations. The strength of evidence
of the scientific data was considered of paramount importance.Consensus ProcessBethesda 2001 was a year-long iterative review process. An Internet
bulletin board was used for discussion of issues and drafts of recommendations.
More than 1000 comments were posted to the bulletin board over the course
of 6 months. The Bethesda Workshop, held April 30-May 2, 2001, was open to
the public. Postworkshop recommendations were posted on the bulletin board
for a last round of critical review prior to finalizing the terminology.ConclusionsBethesda 2001 was developed with broad participation in the consensus
process. The 2001 Bethesda System terminology reflects important advances
in biological understanding of cervical neoplasia and cervical screening technology.read more
Citations
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Journal ArticleDOI
Cervical squamous intra-epithelial changes and human papillomavirus infection in women infected with human immunodeficiency virus in Pune, India.
Smita Joshi,Varanasi Gopalkrishna,B. Kishore Kumar,Soma Dutta,Pratima Nyaynirgune,Madhuri Thakar,Srikanth Tripathy,Sanjay Mehendale,Ramesh S. Paranjape +8 more
TL;DR: In order to prevent thousands of deaths due to cervical cancer in India, there is a need for strengthening the Pap smear screening program and HPV vaccine development.
Journal ArticleDOI
Human papillomavirus infections in women seeking cervical Papanicolaou cytology of Durango, Mexico: prevalence and genotypes.
Luis Francisco Sánchez-Anguiano,Cosme Alvarado-Esquivel,Miguel Arturo Reyes-Romero,Margarita Carrera-Rodríguez +3 more
TL;DR: The prevalence of HPV in women of Durango City is low; however, most infected women have high risk HPV genotypes, which might explain the high rate of mortality for cervical cancer in this region.
Journal ArticleDOI
Identification of progressive cervical epithelial cell abnormalities using DNA image cytometry
TL;DR: The objectives of the current study were to compare the capabilities of conventional cervical cytology and of DNA image cytometry (DNA‐ICM) in the prediction of progressive or regressive behavior in atypical squamous cells (ASC), low‐grade squamous intraepithelial lesions (LSIL), and atypicals glandular cells (AGC).
Journal ArticleDOI
Pilot study of cytological testing for oesophageal squamous cell dysplasia in a high-risk area in Northern Iran
Gholamreza Roshandel,Gholamreza Roshandel,Shahin Merat,M Sotoudeh,Masoud Khoshnia,Hossein Poustchi,Pierre Lao-Sirieix,Shalini Malhotra,Maria O'Donovan,Arash Etemadi,A Nickmanesh,Akram Pourshams,Alireza Norouzi,Irene Debiram,Shahriar Semnani,Christian C. Abnet,Sanford M. Dawsey,Rebecca C. Fitzgerald,Reza Malekzadeh +18 more
TL;DR: The capsule sponge methodology seems to be a feasible, safe, and acceptable method for diagnosing precancerous lesions of the oesophagus in this population, with promising initial accuracy data for the detection of high-grade ESD.
Journal ArticleDOI
The Impact of a Culturally Tailored Patient Navigator Program on Cervical Cancer Prevention in Latina Women
Sanja Percac-Lima,Carly S. Benner,Raymond Lui,Leslie S. Aldrich,Sarah A. Oo,Nessa Regan,Bruce A. Chabner +6 more
TL;DR: Patients navigation can prevent cervical cancer in Latina women by increasing colposcopy clinic attendance, shortening time to colPOScopy, and decreasing severity of cervical abnormalities over time.
References
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Natural history of cervicovaginal papillomavirus infection in young women
TL;DR: An increased risk of HPV infection was significantly associated with younger age, Hispanic ethnicity, black race, an increased number of vaginal-sex partners, high frequencies of vaginal sex and alcohol consumption, anal sex, and certain characteristics of partners.
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Natural History of Cervicovaginal Papillomavirus Infection in Young Women Gyf Ho
TL;DR: The incidence of HPV infection in sexually active young college women is high and the short duration of most HPV infections in these women suggests that the associated cervical dysplasia should be managed conservatively.
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Papillomaviruses Causing Cancer: Evasion From Host-Cell Control in Early Events in Carcinogenesis
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Journal ArticleDOI
2001 Consensus Guidelines for the Management of Women With Cervical Cytological Abnormalities
TL;DR: Management of women with atypical squamous cells (ASC) depends on whether the Papanicolaou test is subcategorized as of undetermined significance (ASC-US) or as cannot exclude high-grade squamous intraepithelial lesion (HSIL) (asc-H).
Journal ArticleDOI
Comparison of Three Management Strategies for Patients With Atypical Squamous Cells of Undetermined Significance: Baseline Results From a Randomized Trial
TL;DR: HC 2 testing for cancer-associated HPV DNA is a viable option in the management of women with ASCUS and has greater sensitivity to detect CIN3 or above and specificity comparable to a single additional cytologic test indicating ASCUS or above.