Journal ArticleDOI
The 2001 Bethesda System: terminology for reporting results of cervical cytology.
Diane Solomon,Diane D. Davey,Robert J. Kurman,Marianne U. Prey,Stephen S. Raab,Mark E. Sherman,David C. Wilbur,Nancy A. Young +7 more
TLDR
The 2001 Bethesda System terminology reflects important advances in biological understanding of cervical neoplasia and cervical screening technology.Abstract:
ObjectivesThe Bethesda 2001 Workshop was convened to evaluate and update the 1991
Bethesda System terminology for reporting the results of cervical cytology.
A primary objective was to develop a new approach to broaden participation
in the consensus process.ParticipantsForum groups composed of 6 to 10 individuals were responsible for developing
recommendations for discussion at the workshop. Each forum group included
at least 1 cytopathologist, cytotechnologist, clinician, and international
representative to ensure a broad range of views and interests. More than 400
cytopathologists, cytotechnologists, histopathologists, family practitioners,
gynecologists, public health physicians, epidemiologists, patient advocates,
and attorneys participated in the workshop, which was convened by the National
Cancer Institute and cosponsored by 44 professional societies. More than 20
countries were represented.EvidenceLiterature review, expert opinion, and input from an Internet bulletin
board were all considered in developing recommendations. The strength of evidence
of the scientific data was considered of paramount importance.Consensus ProcessBethesda 2001 was a year-long iterative review process. An Internet
bulletin board was used for discussion of issues and drafts of recommendations.
More than 1000 comments were posted to the bulletin board over the course
of 6 months. The Bethesda Workshop, held April 30-May 2, 2001, was open to
the public. Postworkshop recommendations were posted on the bulletin board
for a last round of critical review prior to finalizing the terminology.ConclusionsBethesda 2001 was developed with broad participation in the consensus
process. The 2001 Bethesda System terminology reflects important advances
in biological understanding of cervical neoplasia and cervical screening technology.read more
Citations
More filters
Journal ArticleDOI
Clinicopathological significance of atypical glandular cells on cervicovaginal Pap smears.
TL;DR: To evaluate the histologic correlation and clinical significance of atypical glandular cells (AGC) detected on Pap tests, a large number of these cells have been found to have a positive association with Pap smear results.
Journal ArticleDOI
Colposcopy: an evidence-based update.
TL;DR: In this article, evidence-based management strategies are updated with discussion of the 2001 American Society for Colposcopy and Cervical Pathology Consensus Guidelines.
Journal ArticleDOI
Risks factors and timing of genital human papillomavirus (HPV) infection in female stem cell transplant survivors: a longitudinal study
Dana Shanis,Prathima Anandi,Caitlin Grant,Averyl Bachi,Nina Vyas,Melissa A. Merideth,Priyanka A. Pophali,Eleftheria Koklanaris,Sawa Ito,Bipin N. Savani,Austin John Barrett,Minoo Battiwalla,Pamela Stratton +12 more
TL;DR: Persistent, multifocal or severe HPV disease occurred more frequently in women after allogeneic hematopoietic cell transplantation than in healthy populations, and women with extensive cGVHD, genital cGvHD or pre-transplant HPV are at greatest risk for post-trans transplant HPV disease.
Journal ArticleDOI
Distribution of human papillomavirus genotypes in Paraguayan women according to the severity of the cervical lesion.
Laura Mendoza,Juan Arbiza,Malvina Páez,Elena Kasamatsu,Amalia Castro,Graciela Giménez,Jorge Basiletti,Joaquín V. González,Pamela Mongelós,María Alejandra Picconi +9 more
TL;DR: The higher prevalence of HPV 16 and other high‐risk HPVs in women both with and without cervical lesions may explain the high incidence of cervical cancer in Paraguay.
Journal ArticleDOI
Cervical cancer screening with HPV testing in the Valcamonica (Italy) screening programme
L Pasquale,Paolo Giorgi Rossi,Francesca Carozzi,C Pedretti,C Ruggeri,V Scalvinoni,M Cotti Cottini,A Tosini,C Morana,M Chiaramonte,MF Sacristani,R Cirelli,D Chiudinelli,Manuela Piccolomini,Roberta Marchione,Luca Romano,Serena Domenighini,G Pieracci,Massimo Confortini +18 more
TL;DR: HPV-based screening increases colposcopies at the first round, but also strongly increases the detection rate, corroborating the need for longer screening intervals in HPV-negative women.
References
More filters
Journal ArticleDOI
Natural history of cervicovaginal papillomavirus infection in young women
TL;DR: An increased risk of HPV infection was significantly associated with younger age, Hispanic ethnicity, black race, an increased number of vaginal-sex partners, high frequencies of vaginal sex and alcohol consumption, anal sex, and certain characteristics of partners.
Journal ArticleDOI
Natural History of Cervicovaginal Papillomavirus Infection in Young Women Gyf Ho
TL;DR: The incidence of HPV infection in sexually active young college women is high and the short duration of most HPV infections in these women suggests that the associated cervical dysplasia should be managed conservatively.
Journal ArticleDOI
Papillomaviruses Causing Cancer: Evasion From Host-Cell Control in Early Events in Carcinogenesis
TL;DR: Modifications in host-cell genes, most likely engaged in the control of HPV gene expression in proliferating cells, emerge as important events in HPV-mediated carcinogenesis.
Journal ArticleDOI
2001 Consensus Guidelines for the Management of Women With Cervical Cytological Abnormalities
TL;DR: Management of women with atypical squamous cells (ASC) depends on whether the Papanicolaou test is subcategorized as of undetermined significance (ASC-US) or as cannot exclude high-grade squamous intraepithelial lesion (HSIL) (asc-H).
Journal ArticleDOI
Comparison of Three Management Strategies for Patients With Atypical Squamous Cells of Undetermined Significance: Baseline Results From a Randomized Trial
TL;DR: HC 2 testing for cancer-associated HPV DNA is a viable option in the management of women with ASCUS and has greater sensitivity to detect CIN3 or above and specificity comparable to a single additional cytologic test indicating ASCUS or above.