Journal ArticleDOI
The 2001 Bethesda System: terminology for reporting results of cervical cytology.
Diane Solomon,Diane D. Davey,Robert J. Kurman,Marianne U. Prey,Stephen S. Raab,Mark E. Sherman,David C. Wilbur,Nancy A. Young +7 more
TLDR
The 2001 Bethesda System terminology reflects important advances in biological understanding of cervical neoplasia and cervical screening technology.Abstract:
ObjectivesThe Bethesda 2001 Workshop was convened to evaluate and update the 1991
Bethesda System terminology for reporting the results of cervical cytology.
A primary objective was to develop a new approach to broaden participation
in the consensus process.ParticipantsForum groups composed of 6 to 10 individuals were responsible for developing
recommendations for discussion at the workshop. Each forum group included
at least 1 cytopathologist, cytotechnologist, clinician, and international
representative to ensure a broad range of views and interests. More than 400
cytopathologists, cytotechnologists, histopathologists, family practitioners,
gynecologists, public health physicians, epidemiologists, patient advocates,
and attorneys participated in the workshop, which was convened by the National
Cancer Institute and cosponsored by 44 professional societies. More than 20
countries were represented.EvidenceLiterature review, expert opinion, and input from an Internet bulletin
board were all considered in developing recommendations. The strength of evidence
of the scientific data was considered of paramount importance.Consensus ProcessBethesda 2001 was a year-long iterative review process. An Internet
bulletin board was used for discussion of issues and drafts of recommendations.
More than 1000 comments were posted to the bulletin board over the course
of 6 months. The Bethesda Workshop, held April 30-May 2, 2001, was open to
the public. Postworkshop recommendations were posted on the bulletin board
for a last round of critical review prior to finalizing the terminology.ConclusionsBethesda 2001 was developed with broad participation in the consensus
process. The 2001 Bethesda System terminology reflects important advances
in biological understanding of cervical neoplasia and cervical screening technology.read more
Citations
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Journal ArticleDOI
Interlaboratory reproducibility of atypical glandular cells of undetermined significance: a national survey.
Massimo Confortini,L. Di Bonito,Francesca Carozzi,B. Ghiringhello,G. Montanari,F. Parisio,S. Prandi +6 more
TL;DR: The aim of this study was to evaluate the inter‐laboratory reproducibility for atypical glandular cells (AGC) (The Bethesda System (TBS) 2001) of the laboratories involved in the screening programmes in Italy.
Journal ArticleDOI
Cervical Cancer Screening and Updated Pap Guidelines
TL;DR: Screening via Papanicolaou testing is critical, and interpretation of test results with knowledge of patient risk factors is imperative, as well as evidence-based guidelines for screening, interpretation, and management.
Journal ArticleDOI
Cytologically diagnosed Gardnerella vaginalis infection and cervical (pre)neoplasia as established in population-based cervical screening.
TL;DR: Cytologically diagnosed G vaginalis smears show a strong covariation with the presence of cervical (pre)neoplasia, and future research should therefore focus on the exact causal relation between cytologic G vaginal is infection and the existence of (pre-neoplastic changes of the cervix.
Journal ArticleDOI
Distribution of high-risk HPV types among women in Sichuan province, China: a cross-sectional study.
Lixia He,Junyong He +1 more
TL;DR: Overall HR-HPV prevalence in Sichuan is as high as in large cities in China, and high prevalence among women older than 65 years needed pay attention to.
Journal ArticleDOI
Single and Clustered Cervical Cell Classification with Ensemble and Deep Learning Methods
TL;DR: It is shown that using machine vision, ensemble learning and deep learning methods a significant portion of the Pap smear can be done automated, and promise is shown in the creation of an automated Pap smear screening test.
References
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Natural history of cervicovaginal papillomavirus infection in young women
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TL;DR: The incidence of HPV infection in sexually active young college women is high and the short duration of most HPV infections in these women suggests that the associated cervical dysplasia should be managed conservatively.
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Journal ArticleDOI
2001 Consensus Guidelines for the Management of Women With Cervical Cytological Abnormalities
TL;DR: Management of women with atypical squamous cells (ASC) depends on whether the Papanicolaou test is subcategorized as of undetermined significance (ASC-US) or as cannot exclude high-grade squamous intraepithelial lesion (HSIL) (asc-H).
Journal ArticleDOI
Comparison of Three Management Strategies for Patients With Atypical Squamous Cells of Undetermined Significance: Baseline Results From a Randomized Trial
TL;DR: HC 2 testing for cancer-associated HPV DNA is a viable option in the management of women with ASCUS and has greater sensitivity to detect CIN3 or above and specificity comparable to a single additional cytologic test indicating ASCUS or above.