Journal ArticleDOI
The Changing Demographic Pattern of Multiple Sclerosis Epidemiology
TLDR
The literature search and meta-regression analyses indicated an almost universal increase in prevalence and incidence of MS over time; they challenge the well accepted theory of a latitudinal gradient of incidence in Europe and North America, while this gradient is still apparent for Australia and New Zealand; and suggest a general, although not ubiquitous, increase in incidence ofMS in females.Abstract:
Summary The uneven distribution of multiple sclerosis (MS) across populations can be attributed to differences in genes and the environment and their interaction. Prevalence and incidence surveys could be affected by inaccuracy of diagnosis and ascertainment, and prevalence also depends on survival. These sources of error might play a part in the geographical and temporal variations. Our literature search and meta-regression analyses indicated an almost universal increase in prevalence and incidence of MS over time; they challenge the well accepted theory of a latitudinal gradient of incidence of MS in Europe and North America, while this gradient is still apparent for Australia and New Zealand; and suggest a general, although not ubiquitous, increase in incidence of MS in females. The latter observation should prompt epidemiological studies to focus on changes in lifestyle in females. New insights into gene–environment and gene–gene interactions complicate interpretations of demographic epidemiology and have made obsolete the idea of simple causative associations between genes or the environment and MS.read more
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Global, regional, and national burden of neurological disorders, 1990-2016: A systematic analysis for the Global Burden of Disease Study 2016
Valery L. Feigin,Amanuel Alemu Abajobir,Kalkidan Hassen Abate,Foad Abd-Allah,Abdishakur M. Abdulle,Semaw Ferede Abera,Gebre Yitayih Abyu,Muktar Beshir Ahmed,Amani Nidhal Aichour,Ibtihel Aichour,Miloud Taki Eddine Aichour,Rufus Akinyemi,Rufus Akinyemi,Samer Alabed,Rajaa Al-Raddadi,Nelson Alvis-Guzman,Azmeraw T. Amare,Hossein Ansari,Palwasha Anwari,Johan Ärnlöv,Hamid Asayesh,Solomon Weldegebreal Asgedom,Tesfay Mehari Atey,Leticia Avila-Burgos,Euripide Frinel,Euripide Frinel,G. Arthur Avokpaho,Mahmood Reza Azarpazhooh,Aleksandra Barac,Miguel A Barboza,Suzanne Barker-Collo,Till Bärnighausen,Till Bärnighausen,Neeraj Bedi,Ettore Beghi,Derrick A Bennett,Isabela M. Benseñor,Adugnaw Berhane,Balem Demtsu Betsu,Soumyadeep Bhaumik,Sait Mentes Birlik,Stan Biryukov,Dube Jara Boneya,Lemma Negesa Bulto Bulto,Hélène Carabin,Daniel C Casey,Carlos A Castañeda-Orjuela,Ferrán Catalá-López,Honglei Chen,Abdulaal A Chitheer,Rajiv Chowdhury,Hanne Christensen,Lalit Dandona,Lalit Dandona,Rakhi Dandona,Rakhi Dandona,Gabrielle de Veber,Samath D Dharmaratne,Huyen Phuc Do,Klara Dokova,E Ray Dorsey,Richard G. Ellenbogen,Sharareh Eskandarieh,Maryam S. Farvid,Seyed-Mohammad Fereshtehnejad,Florian Fischer,Kyle J Foreman,Kyle J Foreman,Johanna M. Geleijnse,Richard F. Gillum,Giorgia Giussani,Ellen M Goldberg,Philimon Gona,Alessandra C. Goulart,Harish Chander Gugnani,Rahul Gupta,Vladimir Hachinski,Rajeev Gupta,Randah R. Hamadeh,Mitiku Teshome Hambisa,Graeme J. Hankey,Habtamu Abera Hareri,Rasmus Havmoeller,Simon I. Hay,Simon I. Hay,Pouria Heydarpour,Peter J. Hotez,Mihajlo Jakovljevic,Mehdi Javanbakht,Panniyammakal Jeemon,Jost B. Jonas,Yogeshwar Kalkonde,Amit Kandel,André Karch,Amir Kasaeian,Anshul Kastor,Peter Njenga Keiyoro,Yousef Khader,Ibrahim A Khalil,Ejaz Ahmad Khan,Young-Ho Khang,Abdullah Tawfih,Abdullah T Khoja,Jagdish Khubchandani,Chanda Kulkarni,Daniel Kim,Yun Jin Kim,Mika Kivimäki,Mika Kivimäki,Yoshihiro Kokubo,Soewarta Kosen,Michael Kravchenko,Rita Krishnamurthi,Barthelemy Kuate Defo,G Anil Kumar,Rashmi Kumar,Hmwe H Kyu,Anders Larsson,Pablo M. Lavados,Yongmei Li,Xiaofeng Liang,Misgan Legesse Liben,Warren D. Lo,Warren D. Lo,Giancarlo Logroscino,Paulo A. Lotufo,Clement T. Loy,Mark T Mackay,Mark T Mackay,Hassan Magdy Abd El Razek,Mohammed Magdy Abd El Razek,Mohammed Magdy Abd El Razek,Azeem Majeed,Reza Malekzadeh,Treh Manhertz,Lorenzo G. Mantovani,João Massano,Mohsen Mazidi,Colm McAlinden,Suresh Mehata,Man Mohan Mehndiratta,Ziad A. Memish,Walter Mendoza,Mubarek Abera Mengistie,George A. Mensah,Atte Meretoja,Haftay Berhane Mezgebe,Ted R. Miller,Ted R. Miller,Shiva Raj Mishra,Norlinah Mohamed Ibrahim,Alireza Mohammadi,Kedir Endris Mohammed,Shafiu Mohammed,Shafiu Mohammed,Ali H. Mokdad,Maziar Moradi-Lakeh,Ilais Moreno Velásquez,Kamarul Imran Musa,Mohsen Naghavi,Josephine W. Ngunjiri,Cuong Tat Nguyen,Grant Nguyen,Quyen Nguyen,Trang Huyen Nguyen,Emma Nichols,Dina Nur Anggraini Ningrum,Dina Nur Anggraini Ningrum,Vuong Minh Nong,Bo Norrving,Jean Jacques Noubiap,Felix Akpojene Ogbo,Mayowa O. Owolabi,Jeyaraj D Pandian,P. Parmar,David M. Pereira,Max Petzold,Max Petzold,Michael R. Phillips,Michael R. Phillips,Michael A. Piradov,Richie Poulton,Farshad Pourmalek,Mostafa Qorbani,Anwar Rafay,Mahfuzar Rahman,Mohammad Hifz Ur Rahman,Rajesh Kumar Rai,Sasa Rajsic,Annemarei Ranta,Salman Rawaf,Andre M. N. Renzaho,Mohammad Sadegh Rezai,Gregory A. Roth,Gholamreza Roshandel,Gholamreza Roshandel,Enrico Rubagotti,Perminder S. Sachdev,Saeid Safiri,Ramesh Sahathevan,Mohammad Ali Sahraian,Abdallah M. Samy,Paula Santalucia,Itamar S. Santos,Benn Sartorius,Benn Sartorius,Maheswar Satpathy,Monika Sawhney,Mete Saylan,Sadaf G. Sepanlou,Masood Ali Shaikh,Raad Shakir,Morteza Shamsizadeh,Kevin N. Sheth,Mika Shigematsu,Mika Shigematsu,Haitham Shoman,Diego Augusto Santos Silva,Mari Smith,Eugene Sobngwi,Luciano A. Sposato,Jeffrey D. Stanaway,Dan J. Stein,Dan J. Stein,Timothy J. Steiner,Timothy J. Steiner,Lars Jacob Stovner,Rizwan Suliankatchi Abdulkader,Cassandra Szoeke,Rafael Tabarés-Seisdedos,David Tanne,David Tanne,Alice Theadom,Amanda G. Thrift,David L. Tirschwell,Roman Topor-Madry,Roman Topor-Madry,Bach Xuan Tran,Bach Xuan Tran,Thomas Truelsen,Kald Beshir Tuem,Kingsley N. Ukwaja,Olalekan A. Uthman,Yuri Y Varakin,Tommi Vasankari,Narayanaswamy Venketasubramanian,Vasiliy Victorovich Vlassov,Fiseha Wadilo,Tolassa Wakayo,Mitchell T. Wallin,Mitchell T. Wallin,Elisabete Weiderpass,Ronny Westerman,Tissa Wijeratne,Charles Shey Wiysonge,Charles Shey Wiysonge,Minyahil Alebachew Woldu,Minyahil Alebachew Woldu,Charles D.A. Wolfe,Charles D.A. Wolfe,Denis Xavier,Gelin Xu,Yuichiro Yano,Hassen Hamid Yimam,Naohiro Yonemoto,Chuanhua Yu,Zoubida Zaidi,Maysaa El Sayed Zaki,Joseph R. Zunt,Christopher J L Murray,Theo Vos +270 more
TL;DR: The Global Burden of Diseases, Injuries, and Risk Factors (GBD) study provides such information but does not routinely aggregate results that are of interest to clinicians specialising in neurological conditions as discussed by the authors.
Journal ArticleDOI
Global, regional, and national burden of neurological disorders during 1990-2015
Valery L. Feigin,Amanuel Alemu Abajobir,Kalkidan Hassen Abate,Foad Abd-Allah,Abdishakur M. Abdulle,Semaw Ferede Abera,Gebre Yitayih Abyu,Muktar Beshir Ahmed,Amani Nidhal Aichour,Ibtihel Aichour,Miloud Taki Eddine Aichour,Rufus Akinyemi,Samer Alabed,Rajaa Al-Raddadi,Nelson Alvis-Guzman,Azmeraw T. Amare,Hossein Ansari,Palwasha Anwari,Johan Ärnlöv,Hamid Asayesh,Solomon Weldegebreal Asgedom,Tesfay Mehari Atey,Leticia Avila-Burgos,Euripide Frinel G Arthur Avokpaho,Mahmood Reza Azarpazhooh,Aleksandra Barac,Miguel A Barboza,Suzanne Barker-Collo,Till Baernighausen,Neeraj Bedi,Ettore Beghi,Derrick A Bennett,Isabela M. Benseñor,Adugnaw Berhane,Balem Demtsu Betsu,Soumyadeep Bhaumik,Sait Mentes Birlik,Stan Biryukov,Dube Jara Boneya,Lemma NegesaBulto Bulto,Hélène Carabin,Daniel C Casey,Carlos A Castañeda-Orjuela,Ferrán Catalá-López,Honglei Chen,Abdulaal A Chitheer,Rajiv Chowdhury,Hanne Christensen,Lalit Dandona,Rakhi Dandona,Gabrielle deVeber,Samath D Dharmaratne,Huyen Phuc Do,Klara Dokova,E. Ray Dorsey,Richard G. Ellenbogen,Sharareh Eskandarieh,Maryam S. Farvid,Seyed-Mohammad Fereshtehnejad,Florian Fischer,Kyle J Foreman,Johanna M. Geleijnse,Richard F. Gillum,Giorgia Giussani,Ellen M Goldberg,Philimon Gona,Alessandra C. Goulart,Harish Chander Gugnani,Rashmi Gupta,Rajeev Gupta,Vladimir Hachinski,Randah R. Hamadeh,Mitiku Teshome Hambisa,Graeme J. Hankey,Habtamu Abera Hareri,Rasmus Havmoeller,Simon I. Hay,Pouria Heydarpour,Peter J. Hotez,Mihajlo Jakovljevic,Mehdi Javanbakht,Panniyammakal Jeemon,Jost B. Jonas,Yogeshwar Kalkonde,Amit Kandel,André Karch,Amir Kasaeian,Anshul Kastor,Peter Njenga Keiyoro,Yousef Khader,Ibrahim A Khalil,Ejaz Ahmad Khan,Young-Ho Khang,Abdullah T Khoja,Jagdish Khubchandani,Chanda Kulkarni,Daniel Kim,Yun Jin Kim,Mika Kivimäki,Yoshihiro Kokubo,Soewarta Kosen,Michael Kravchenko,Rita Krishnamurthi,Barthelemy Kuate Defo,G Anil Kumar,Rashmi Kumar,Hmwe H Kyu,Anders Larsson,Pablo M. Lavados,Yongmei Li,Xiaofeng Liang,Misgan Legesse Liben,Warren D. Lo,Giancarlo Logroscino,Paulo A. Lotufo,Clement T. Loy,Mark T Mackay,Hassan Magdy Abd El Razek,Mohammed Magdy Abd El Razek,Azeem Majeed,Reza Malekzadeh,Treh Manhertz,Lorenzo G. Mantovani,João Massano,Mohsen Mazidi,Colm McAlinden,Suresh Mehata,Man Mohan Mehndiratta,Ziad A. Memish,Walter Mendoza,Mubarek Abera Mengistie,George A. Mensah,Atte Meretoja,Haftay Berhane Mezgebe,Ted R. Miller,Shiva Raj Mishra,Norlinah Mohamed Ibrahim,Alireza Mohammadi,Kedir Endris Mohammed,Shafiu Mohammed,Ali H. Mokdad,Maziar Moradi-Lakeh,Ilais Moreno Velásquez,Kamarul Imran Musa,Mohsen Naghavi,Josephine W. Ngunjiri,Cuong Tat Nguyen,Grant Nguyen,Quyen Nguyen,Trang Huyen Nguyen,Emma Nichols,Dina Nur Anggraini Ningrum,Vuong Minh Nong,Bo Norrving,Jean Jacques Noubiap,Felix Akpojene Ogbo,Mayowa O. Owolabi,Jeyaraj D Pandian,P. Parmar,David M. Pereira,Max Petzold,Michael R. Phillips,Michael A. Piradov,Richie Poulton,Farshad Pourmalek,Mostafa Qorbani,Anwar Rafay,Mahfuzar Rahman,Mohammad Hifz Ur Rahman,Rajesh Kumar Rai,Sasa Rajsic,Annemarei Ranta,Salman Rawaf,Andre M. N. Renzaho,Mohammad Sadegh Rezai,Gregory A. Roth,Gholamreza Roshandel,Enrico Rubagotti,Perminder S. Sachdev,Saeid Safiri,Ramesh Sahathevan,Mohammad Ali Sahraian,Abdallah M. Samy,Paula Santalucia,Itamar S. Santos,Benn Sartorius,Maheswar Satpathy,Monika Sawhney,Mete Saylan,Sadaf G. Sepanlou,Masood Ali Shaikh,Raad Shakir,Morteza Shamsizadeh,Kevin N. Sheth,Mika Shigematsu,Haitham Shoman,Diego Augusto Santos Silva,Mari Smith,Eugene Sobngwi,Luciano A. Sposato,Jeffrey D. Stanaway,Dan J. Stein,Timothy J. Steiner,Lars Jacob Stovner,Rizwan Suliankatchi Abdulkader,Cassandra Szoeke,Rafael Tabarés-Seisdedos,David Tanne,Alice Theadom,Amanda G. Thrift,David L. Tirschwell,Roman Topor-Madry,Bach Xuan Tran,Thomas Truelsen,Kald Beshir Tuem,Kingsley N. Ukwaja,Olalekan A. Uthman,Yuri Y Varakin,Tommi Vasankari,Narayanaswamy Venketasubramanian,Vasiliy Victorovich Vlassov,Fiseha Wadilo,Tolassa Wakayo,Mitchell T. Wallin,Elisabete Weiderpass,Ronny Westerman,Tissa Wijeratne,Charles Shey Wiysonge,Minyahil Alebachew Woldu,Charles D.A. Wolfe,Denis Xavier,Gelin Xu,Yuichiro Yano,Hassen Hamid Yimam,Naohiro Yonemoto,Chuanhua Yu,Zoubida Zaidi,Maysaa El Sayed Zaki,Joseph R. Zunt,Christopher J L Murray,Theo Vos,Gbd Neurological Disorders +241 more
Journal ArticleDOI
Multiple Sclerosis - A Review
Ruth Dobson,Gavin Giovannoni +1 more
TL;DR: The epidemiology of MS indicates that low serum levels of vitamin D, smoking, childhood obesity and infection with the Epstein–Barr virus are likely to play a role in disease development, and potentially preventive strategies could be studied.
Journal ArticleDOI
Interactions between genetic, lifestyle and environmental risk factors for multiple sclerosis
TL;DR: Strong evidence now supports obesity during adolescence as a factor increasing MS risk, and recent data on environmental and lifestyle factors are reviewed, with a focus on gene–environment interactions.
Journal ArticleDOI
Global, regional, and national burden of multiple sclerosis 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016
Mitchell T. Wallin,William J. Culpepper,Emma Nichols,Zulfiqar A Bhutta,Tsegaye Tewelde Gebrehiwot,Simon I. Hay,Ibrahim A Khalil,Kristopher J Krohn,Xiaofeng Liang,Mohsen Naghavi,Ali H. Mokdad,Molly R Nixon,Robert Reiner,Benn Sartorius,Mari Smith,Roman Topor-Madry,Andrea Werdecker,Theo Vos,Valery L. Feigin,Christopher J L Murray +19 more
TL;DR: The global burden of multiple sclerosis and its relationship with country development level and the Socio-demographic Index, a composite indicator of income per person, years of education, and fertility, is quantified to assess relations with development level.
References
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Recommended diagnostic criteria for multiple sclerosis: Guidelines from the International Panel on the Diagnosis of Multiple Sclerosis
W. Ian McDonald,A Compston,Gilles Edan,Donald E. Goodkin,Hans-Peter Hartung,Fred D. Lublin,Henry F. McFarland,Donald W. Paty,Chris H. Polman,Stephen C. Reingold,Magnhild Sandberg-Wollheim,William A. Sibley,Alan J. Thompson,Stanley van den Noort,Brian Y. Weinshenker,Jerry S. Wolinsky +15 more
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Diagnostic criteria for multiple sclerosis: 2010 Revisions to the McDonald criteria
Chris H. Polman,Stephen C. Reingold,Brenda Banwell,Michel Clanet,Jeffrey A. Cohen,Massimo Filippi,Kazuo Fujihara,Eva Havrdova,Michael Hutchinson,Ludwig Kappos,Fred D. Lublin,Xavier Montalban,Paul L. O’Connor,Magnhild Sandberg-Wollheim,Alan J. Thompson,Emmanuelle Waubant,Brian G. Weinshenker,Jerry S. Wolinsky +17 more