The effects of combined micron-/submicron-scale surface roughness and nanoscale features on cell proliferation and differentiation
Rolando A. Gittens,Taylor McLachlan,Rene Olivares-Navarrete,Ye Cai,Simon Berner,Rina Tannenbaum,Zvi Schwartz,Kenneth H. Sandhage,Barbara D. Boyan +8 more
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TLDR
The results suggested that the introduction of such nanoscale structures in combination with micro-/submicro-scale roughness improves osteoblast differentiation and local factor production, which indicates the potential for improved implant osseointegration in vivo.About:
This article is published in Biomaterials.The article was published on 2011-05-01 and is currently open access. It has received 703 citations till now. The article focuses on the topics: Surface roughness & Nanotopography.read more
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Journal ArticleDOI
Improved Cell Adhesion and Osseointegration on Anodic Oxidation Modified Titanium Implant Surface
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A physicochemical approach to design bioactive scaffolds for tissue engineering
TL;DR: A submitted manuscript is the version of the article upon submission and before peer-review as mentioned in this paper, while a published version is the final layout of the paper including the volume, issue and page numbers.
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Designing biocompatible spin-coated multiwall carbon nanotubes-polymer composite coatings
Damian Maziukiewicz,Barbara M. Maciejewska,Jagoda Litowczenko,Mikołaj Kościński,Alicja Warowicka,Jacek K. Wychowaniec,Stefan Jurga +6 more
TL;DR: In this article, the authors combined two polymers of different hydrophobic character: poly(maleic-alt-1-octadecene) and polyvinylpyrrolidone with multi-walled carbon nanotubes (MWCNTs) to produce composite coatings with varied hydrophobicity.
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Surface characterization and fatigue performance of a chemical-etched Ti-6Al-4V femoral stem for cementless hip arthroplasty
Bruno José Silva de Oliveira,Leonardo Contri Campanelli,D.P. Oliveira,Ana Paula de Bribean Guerra,Claudemiro Bolfarini +4 more
TL;DR: In this article, the influence of a two-step chemical etching on the surface characteristics, coating properties and fatigue performance of a finished Ti-6Al-4V femoral stem early coated with Ti powder by thermal plasma spraying (namely TPS) was investigated.
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Pulsed laser-deposited composite carbon–glass–ceramic films with improved hardness
TL;DR: In this article, a composite material obtained by mixing a glass-ceramic powder and C60 has been used to obtain thin films by nanosecond pulsed laser deposition technique, with the aim to improve the mechanical properties of the potentially bioactive coatings.
References
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Mechanical properties and the hierarchical structure of bone
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Influence of surface characteristics on bone integration of titanium implants. A histomorphometric study in miniature pigs.
Daniel Buser,Robert K. Schenk,S. G. Steinemann,Joseph P. Fiorellini,Christopher H. Fox,H. Stich +5 more
TL;DR: The extent of bone-implant interface is positively correlated with an increasing roughness of the implant surface, and hydroxylapatite (HA)-coated implants with 60-70% showed signs of resorption.
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Genetic regulation of osteoclast development and function
TL;DR: The past five years have witnessed important insights into osteoclast formation and function and many of these discoveries have been made through genetic experiments that involved the rare hereditary disorder osteopetrosis.
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Enhanced functions of osteoblasts on nanophase ceramics
TL;DR: The results of the present study provided the first evidence of enhanced long-term (on the order of days to weeks) functions of osteoblasts cultured on nanophase ceramics, and clearly represent a unique and promising class of orthopaedic/dental implant formulations with improved osseointegrative properties.
Journal ArticleDOI
Effect of titanium surface roughness on proliferation, differentiation, and protein synthesis of human osteoblast-like cells (MG63)
J. Y. Martin,Zvi Schwartz,Thomas W. Hummert,D. M. Schraub,J. Simpson,J. Lankford,David D Dean,David L. Cochran,Barbara D. Boyan +8 more
TL;DR: It is demonstrated that surface roughness alters osteoblast proliferation, differentiation, and matrix production in vitro and suggests that implant surfaceroughness may play a role in determining phenotypic expression of cells in vivo.
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