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The Health Effects of Cannabis and Cannabinoids: The Current State of Evidence and Recommendations for Research

Eric Groce
- Vol. 104, Iss: 4, pp 32-32
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TLDR
Despite increased cannabis use and a changing state-level policy landscape, conclusive evidence regarding the shortand long-term health effects—both harms and benefits—of cannabis use remains elusive.
Abstract
Recent years have seen a rapid rise in the medical and recreational use of cannabis: a broad term that can be used to describe the various products and chemical compounds (e.g., marijuana, cannabinoids) derived from different species of the cannabis plant. Despite increased cannabis use and a changing state-level policy landscape, conclusive evidence regarding the shortand long-term health effects—both harms and benefits—of cannabis use remains elusive.

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Citations
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Journal ArticleDOI

Epidemiology of Adult DSM-5 Major Depressive Disorder and Its Specifiers in the United States.

TL;DR: Both anxious/distressed specifier and mixed-features specifier were associated with early onset, poor course and functioning, and suicidality in US adults, and much remains to be learned about the DSM-5 MDD specifiers in the general population.
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Association of Cannabis Use in Adolescence and Risk of Depression, Anxiety, and Suicidality in Young Adulthood: A Systematic Review and Meta-analysis.

TL;DR: Although individual-level risk remains moderate to low and results from this study should be confirmed in future adequately powered prospective studies, the high prevalence of adolescents consuming cannabis generates a large number of young people who could develop depression and suicidality attributable to cannabis.
Journal ArticleDOI

US Epidemiology of Cannabis Use and Associated Problems

TL;DR: An overview of the changing US epidemiology of cannabis use and associated problems suggests national increases in cannabis potency, prenatal and unintentional childhood exposure; and in adults, increased use, CUD, cannabis-related emergency room visits, and fatal vehicle crashes.
Journal ArticleDOI

Cannabis and cannabinoids for the treatment of people with chronic noncancer pain conditions: a systematic review and meta-analysis of controlled and observational studies.

TL;DR: It seems unlikely that cannabinoids are highly effective medicines for CNCP, as effects suggest that number needed to treat to benefit is high, and number neededto treat to harm is low, with limited impact on other domains.
Journal ArticleDOI

Cannabinoids for the treatment of mental disorders and symptoms of mental disorders: a systematic review and meta-analysis

TL;DR: There is scarce evidence to suggest that cannabinoids improve depressive disorders and symptoms, anxiety disorders, attention-deficit hyperactivity disorder, Tourette syndrome, post-traumatic stress disorder, or psychosis.
References
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Journal ArticleDOI

Exogenous lipid pneumonia related to smoking weed oil following cadaveric renal transplantation.

TL;DR: A 30-year-old female presented shortly after cadaveric renal transplantation with respiratory distress typical of a bacterial infection, which revealed a pulmonary alveolar proteinosis (PAP) reaction and exogenous lipid pneumonia (ELP).
Journal ArticleDOI

Trajectories of marijuana use from adolescence to adulthood predicting unemployment in the mid 30s.

TL;DR: The results suggest that those who use marijuana chronically are at greater risk for being unemployed and should have access to and participate in marijuana cessation treatment programs in order to reduce their risk of unemployment.
Journal ArticleDOI

Effect of illegal substance use on cognitive function in individuals with a psychotic disorder: a review and meta-analysis.

TL;DR: An overview of the literature that has investigated the effect of illegal substance abuse or dependence on cognitive function in those with a psychotic disorder is given and a meta-analysis shows that substance users performed significantly better than nonusers in the cognitive domains of attention and psychomotor speed and verbal memory.
Journal ArticleDOI

Preparation and Distribution of Cannabis and Cannabis-Derived Dosage Formulations for Investigational and Therapeutic Use in the United States

TL;DR: In this article, the analytical and regulatory system that need to be put in place to ensure standardization for the researcher and to reduce the hazards of contamination, overdosing and underdosing for the end-user is discussed.
Journal ArticleDOI

Adverse psychosocial outcomes associated with drug use among US high school seniors: a comparison of alcohol and marijuana

TL;DR: Marijuana and alcohol are associated with unique adverse psychosocial outcomes that differ by sex and race/ethnicity, and public health interventions may be more effective by focusing on harm reduction strategies for these drug-specific outcomes.
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Is cannabis oil good for health?

The paper does not specifically mention cannabis oil, but it discusses the health effects of cannabis and cannabinoids in general.