The Health Effects of Cannabis and Cannabinoids: The Current State of Evidence and Recommendations for Research
Eric Groce
- Vol. 104, Iss: 4, pp 32-32
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TLDR
Despite increased cannabis use and a changing state-level policy landscape, conclusive evidence regarding the shortand long-term health effects—both harms and benefits—of cannabis use remains elusive.Abstract:
Recent years have seen a rapid rise in the medical and recreational use of cannabis: a broad term that can be used to describe the various products and chemical compounds (e.g., marijuana, cannabinoids) derived from different species of the cannabis plant. Despite increased cannabis use and a changing state-level policy landscape, conclusive evidence regarding the shortand long-term health effects—both harms and benefits—of cannabis use remains elusive.read more
Citations
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Journal ArticleDOI
Epidemiology of Adult DSM-5 Major Depressive Disorder and Its Specifiers in the United States.
Deborah S. Hasin,Deborah S. Hasin,Deborah S. Hasin,Aaron L. Sarvet,Aaron L. Sarvet,Jacquelyn L. Meyers,Tulshi D. Saha,W. June Ruan,Malka Stohl,Bridget F. Grant +9 more
TL;DR: Both anxious/distressed specifier and mixed-features specifier were associated with early onset, poor course and functioning, and suicidality in US adults, and much remains to be learned about the DSM-5 MDD specifiers in the general population.
Journal ArticleDOI
Association of Cannabis Use in Adolescence and Risk of Depression, Anxiety, and Suicidality in Young Adulthood: A Systematic Review and Meta-analysis.
Gabriella Gobbi,Tobias Atkin,Tomasz Zytynski,Shouao Wang,Sorayya Askari,Sorayya Askari,Jill Boruff,Mark A. Ware,Naomi R. Marmorstein,Andrea Cipriani,Andrea Cipriani,Nandini Dendukuri,Nancy E. Mayo,Nancy E. Mayo +13 more
TL;DR: Although individual-level risk remains moderate to low and results from this study should be confirmed in future adequately powered prospective studies, the high prevalence of adolescents consuming cannabis generates a large number of young people who could develop depression and suicidality attributable to cannabis.
Journal ArticleDOI
US Epidemiology of Cannabis Use and Associated Problems
TL;DR: An overview of the changing US epidemiology of cannabis use and associated problems suggests national increases in cannabis potency, prenatal and unintentional childhood exposure; and in adults, increased use, CUD, cannabis-related emergency room visits, and fatal vehicle crashes.
Journal ArticleDOI
Cannabis and cannabinoids for the treatment of people with chronic noncancer pain conditions: a systematic review and meta-analysis of controlled and observational studies.
Emily Stockings,Gabrielle Campbell,Wayne Hall,Suzanne Nielsen,Dino Zagic,Rakin Rahman,Bridin Murnion,Michael Farrell,Megan Weier,Louisa Degenhardt +9 more
TL;DR: It seems unlikely that cannabinoids are highly effective medicines for CNCP, as effects suggest that number needed to treat to benefit is high, and number neededto treat to harm is low, with limited impact on other domains.
Journal ArticleDOI
Cannabinoids for the treatment of mental disorders and symptoms of mental disorders: a systematic review and meta-analysis
Nicola Black,Emily Stockings,Gabrielle Campbell,Lucy Thi Tran,Dino Zagic,Wayne Hall,Michael Farrell,Louisa Degenhardt +7 more
TL;DR: There is scarce evidence to suggest that cannabinoids improve depressive disorders and symptoms, anxiety disorders, attention-deficit hyperactivity disorder, Tourette syndrome, post-traumatic stress disorder, or psychosis.
References
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Journal ArticleDOI
Statistics on Cannabis Users Skew Perceptions of Cannabis Use
TL;DR: Focusing on days of use instead of prevalence shows substantially greater increases in U.S. cannabis use in recent years, suggesting consumption is even more skewed toward the minority of heavy users than is suggested by days-of-use calculations.
Journal ArticleDOI
Gender differences in the associations among marijuana use, cigarette use, and symptoms of depression during adolescence and young adulthood.
TL;DR: Marijuana use is strongly related to depression symptoms and cigarette use frequency in males, indicating that in males these detrimental factors converge, whereas in females they do not.
Journal ArticleDOI
A prospective study on intrauterine cannabis exposure and fetal blood flow
Hanan El Marroun,Hanan El Marroun,Henning Tiemeier,Eric A.P. Steegers,Jolien W. Roos-Hesselink,Vincent W. V. Jaddoe,Albert Hofman,Frank C. Verhulst,Wim van den Brink,Anja C. Huizink,Anja C. Huizink +10 more
TL;DR: The findings suggest that intrauterine cannabis exposure was associated with changes in hemodynamic programming of the vascular system of the fetus in late pregnancy mainly due to tobacco exposure, but intrauterines cannabis exposure did demonstrate a specific effect on the uterine blood flow.
Journal ArticleDOI
Relationships between frequency of driving under the influence of cannabis, self-reported reckless driving and risk-taking behavior observed in a driving simulator
Jacques Bergeron,Martin Paquette +1 more
TL;DR: Results show that people admitting that they commit more real-life dangerous driving behaviors reached higher maximum speed and demonstrated more reckless driving behaviors on the driving simulation tasks and support the problem driving behavior theory.
Journal ArticleDOI
The Gateway Hypothesis, Common Liability to Addictions or the Route of Administration Model? A Modelling Process Linking the Three Theories
TL;DR: While the most likely initiation sequence among subjects who initiated the 3 groups of substances was the ‘gateway' sequence T → C → OID, this pattern was not associated with substance use propensity more than alternative sequences, and RAM could explain reciprocal interactions observed between T and C.