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The Health Effects of Cannabis and Cannabinoids: The Current State of Evidence and Recommendations for Research

Eric Groce
- Vol. 104, Iss: 4, pp 32-32
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TLDR
Despite increased cannabis use and a changing state-level policy landscape, conclusive evidence regarding the shortand long-term health effects—both harms and benefits—of cannabis use remains elusive.
Abstract
Recent years have seen a rapid rise in the medical and recreational use of cannabis: a broad term that can be used to describe the various products and chemical compounds (e.g., marijuana, cannabinoids) derived from different species of the cannabis plant. Despite increased cannabis use and a changing state-level policy landscape, conclusive evidence regarding the shortand long-term health effects—both harms and benefits—of cannabis use remains elusive.

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Citations
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Journal ArticleDOI

Epidemiology of Adult DSM-5 Major Depressive Disorder and Its Specifiers in the United States.

TL;DR: Both anxious/distressed specifier and mixed-features specifier were associated with early onset, poor course and functioning, and suicidality in US adults, and much remains to be learned about the DSM-5 MDD specifiers in the general population.
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Association of Cannabis Use in Adolescence and Risk of Depression, Anxiety, and Suicidality in Young Adulthood: A Systematic Review and Meta-analysis.

TL;DR: Although individual-level risk remains moderate to low and results from this study should be confirmed in future adequately powered prospective studies, the high prevalence of adolescents consuming cannabis generates a large number of young people who could develop depression and suicidality attributable to cannabis.
Journal ArticleDOI

US Epidemiology of Cannabis Use and Associated Problems

TL;DR: An overview of the changing US epidemiology of cannabis use and associated problems suggests national increases in cannabis potency, prenatal and unintentional childhood exposure; and in adults, increased use, CUD, cannabis-related emergency room visits, and fatal vehicle crashes.
Journal ArticleDOI

Cannabis and cannabinoids for the treatment of people with chronic noncancer pain conditions: a systematic review and meta-analysis of controlled and observational studies.

TL;DR: It seems unlikely that cannabinoids are highly effective medicines for CNCP, as effects suggest that number needed to treat to benefit is high, and number neededto treat to harm is low, with limited impact on other domains.
Journal ArticleDOI

Cannabinoids for the treatment of mental disorders and symptoms of mental disorders: a systematic review and meta-analysis

TL;DR: There is scarce evidence to suggest that cannabinoids improve depressive disorders and symptoms, anxiety disorders, attention-deficit hyperactivity disorder, Tourette syndrome, post-traumatic stress disorder, or psychosis.
References
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Journal ArticleDOI

Are adolescents who moderate their cannabis use at lower risk of later regular and dependent cannabis use

TL;DR: By age 24, both occasional use groups were at similar, elevated risk of regular and dependent cannabis use compared to non-users, and Weekly+ adolescent users were at greatest risk of these outcomes, although the weekly to abstinence group exhibited lower risk than those in the weekly persisting and weekly to occasional groups, who was at similar risk.
Journal Article

Vital Signs: Health Burden and Medical Costs of Nonfatal Injuries to Motor Vehicle Occupants — United States, 2012

TL;DR: The purpose of this study was to describe the current health burden and medical and work loss costs of nonfatal crash injuries among vehicle occupants in the United States and suggest ways to reduce associated ED visits, hospitalizations, and medical costs.
Journal ArticleDOI

The effect of drug use on workplace accidents

TL;DR: In this article, the authors examined the relationship between illicit drug use and workplace accidents among young adults in the United States in two complementary ways: whether individuals who use drugs are more likely than their non-using counterparts to experience an accident on the job, and the individual's consumption choices.
Journal ArticleDOI

Risk factors for placental abruption in a socio-economically disadvantaged region

TL;DR: In this high-risk population, PRE-PROM and elevated homocysteine levels appear to represent the major risk factors for placental abruption.
Journal ArticleDOI

Chronic necrotizing pulmonary aspergillosis in a patient with diabetes and marijuana use

TL;DR: A29-year-old man with type 1 diabetes presented to the emergency department with shortness of breath and chest pain that had lasted for one week and stated that he had felt generally unwell for the past year.
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