The Health Effects of Cannabis and Cannabinoids: The Current State of Evidence and Recommendations for Research
Eric Groce
- Vol. 104, Iss: 4, pp 32-32
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TLDR
Despite increased cannabis use and a changing state-level policy landscape, conclusive evidence regarding the shortand long-term health effects—both harms and benefits—of cannabis use remains elusive.Abstract:
Recent years have seen a rapid rise in the medical and recreational use of cannabis: a broad term that can be used to describe the various products and chemical compounds (e.g., marijuana, cannabinoids) derived from different species of the cannabis plant. Despite increased cannabis use and a changing state-level policy landscape, conclusive evidence regarding the shortand long-term health effects—both harms and benefits—of cannabis use remains elusive.read more
Citations
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Journal ArticleDOI
Epidemiology of Adult DSM-5 Major Depressive Disorder and Its Specifiers in the United States.
Deborah S. Hasin,Deborah S. Hasin,Deborah S. Hasin,Aaron L. Sarvet,Aaron L. Sarvet,Jacquelyn L. Meyers,Tulshi D. Saha,W. June Ruan,Malka Stohl,Bridget F. Grant +9 more
TL;DR: Both anxious/distressed specifier and mixed-features specifier were associated with early onset, poor course and functioning, and suicidality in US adults, and much remains to be learned about the DSM-5 MDD specifiers in the general population.
Journal ArticleDOI
Association of Cannabis Use in Adolescence and Risk of Depression, Anxiety, and Suicidality in Young Adulthood: A Systematic Review and Meta-analysis.
Gabriella Gobbi,Tobias Atkin,Tomasz Zytynski,Shouao Wang,Sorayya Askari,Sorayya Askari,Jill Boruff,Mark A. Ware,Naomi R. Marmorstein,Andrea Cipriani,Andrea Cipriani,Nandini Dendukuri,Nancy E. Mayo,Nancy E. Mayo +13 more
TL;DR: Although individual-level risk remains moderate to low and results from this study should be confirmed in future adequately powered prospective studies, the high prevalence of adolescents consuming cannabis generates a large number of young people who could develop depression and suicidality attributable to cannabis.
Journal ArticleDOI
US Epidemiology of Cannabis Use and Associated Problems
TL;DR: An overview of the changing US epidemiology of cannabis use and associated problems suggests national increases in cannabis potency, prenatal and unintentional childhood exposure; and in adults, increased use, CUD, cannabis-related emergency room visits, and fatal vehicle crashes.
Journal ArticleDOI
Cannabis and cannabinoids for the treatment of people with chronic noncancer pain conditions: a systematic review and meta-analysis of controlled and observational studies.
Emily Stockings,Gabrielle Campbell,Wayne Hall,Suzanne Nielsen,Dino Zagic,Rakin Rahman,Bridin Murnion,Michael Farrell,Megan Weier,Louisa Degenhardt +9 more
TL;DR: It seems unlikely that cannabinoids are highly effective medicines for CNCP, as effects suggest that number needed to treat to benefit is high, and number neededto treat to harm is low, with limited impact on other domains.
Journal ArticleDOI
Cannabinoids for the treatment of mental disorders and symptoms of mental disorders: a systematic review and meta-analysis
Nicola Black,Emily Stockings,Gabrielle Campbell,Lucy Thi Tran,Dino Zagic,Wayne Hall,Michael Farrell,Louisa Degenhardt +7 more
TL;DR: There is scarce evidence to suggest that cannabinoids improve depressive disorders and symptoms, anxiety disorders, attention-deficit hyperactivity disorder, Tourette syndrome, post-traumatic stress disorder, or psychosis.
References
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Journal ArticleDOI
Cannabis smoking and lung cancer risk: Pooled analysis in the International Lung Cancer Consortium
Li Rita Zhang,Hal Morgenstern,Sander Greenland,Shen Chih Chang,Philip Lazarus,M. Dawn Teare,Penella J. Woll,Irene Orlow,Brian Cox,Yonathan Brhane,Geoffrey Liu,Rayjean J. Hung +11 more
TL;DR: Results from the pooled analyses provide little evidence for an increased risk of lung cancer among habitual or long‐term cannabis smokers, although the possibility of potential adverse effect for heavy consumption cannot be excluded.
Journal ArticleDOI
Open label evaluation of cannabidiol in dystonic movement disorders.
TL;DR: Cannabidiol (CBD), a nonpsychoactive cannabinoid of Cannabis, was given to 5 patients with dystonic movement disorders in a preliminary open pilot study and appears to have antidystonic and Parkinsonism-aggravating effects in humans.
Journal ArticleDOI
Effect of intrapulmonary tetrahydrocannabinol administration in humans
Lineke Zuurman,C. Roy,Rik C. Schoemaker,Arno Hazekamp,J. den Hartigh,Jcme Bender,Robert Verpoorte,Jean-Louis Pinquier,Adam F. Cohen,Jma van Gerven +9 more
TL;DR: Very low between-subject variability was observed in THC plasma concentrations, characterising the Volcano® vaporizer as a suitable method for the administration of THC, and the results may be applicable in the development of novel cannabinoid agonists and antagonists, and in studies of the pharmacology and physiology of cannabinoid systems in humans.
Journal ArticleDOI
Progression from marijuana use to daily smoking and nicotine dependence in a national sample of U.S. adolescents
David S. Timberlake,Brett C. Haberstick,Christian J. Hopfer,Josh B. Bricker,Joseph T. Sakai,Jeffrey M. Lessem,John K. Hewitt +6 more
TL;DR: The use of marijuana in adolescence was modestly associated with daily cigarette smoking and nicotine dependence in young adulthood, and age at first use of cannabis was negatively associated with risk of Nicotine dependence in the older, but not younger cohort.
Journal ArticleDOI
The effects of cannabis use on neurocognition in schizophrenia: A meta-analysis
TL;DR: Effect size differences in cognitive performance in the schizophrenia group as a function of cannabis use were in the small to medium range, denoting superior performance in cannabis-using patients.