The Health Effects of Cannabis and Cannabinoids: The Current State of Evidence and Recommendations for Research
Eric Groce
- Vol. 104, Iss: 4, pp 32-32
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TLDR
Despite increased cannabis use and a changing state-level policy landscape, conclusive evidence regarding the shortand long-term health effects—both harms and benefits—of cannabis use remains elusive.Abstract:
Recent years have seen a rapid rise in the medical and recreational use of cannabis: a broad term that can be used to describe the various products and chemical compounds (e.g., marijuana, cannabinoids) derived from different species of the cannabis plant. Despite increased cannabis use and a changing state-level policy landscape, conclusive evidence regarding the shortand long-term health effects—both harms and benefits—of cannabis use remains elusive.read more
Citations
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Journal ArticleDOI
Epidemiology of Adult DSM-5 Major Depressive Disorder and Its Specifiers in the United States.
Deborah S. Hasin,Deborah S. Hasin,Deborah S. Hasin,Aaron L. Sarvet,Aaron L. Sarvet,Jacquelyn L. Meyers,Tulshi D. Saha,W. June Ruan,Malka Stohl,Bridget F. Grant +9 more
TL;DR: Both anxious/distressed specifier and mixed-features specifier were associated with early onset, poor course and functioning, and suicidality in US adults, and much remains to be learned about the DSM-5 MDD specifiers in the general population.
Journal ArticleDOI
Association of Cannabis Use in Adolescence and Risk of Depression, Anxiety, and Suicidality in Young Adulthood: A Systematic Review and Meta-analysis.
Gabriella Gobbi,Tobias Atkin,Tomasz Zytynski,Shouao Wang,Sorayya Askari,Sorayya Askari,Jill Boruff,Mark A. Ware,Naomi R. Marmorstein,Andrea Cipriani,Andrea Cipriani,Nandini Dendukuri,Nancy E. Mayo,Nancy E. Mayo +13 more
TL;DR: Although individual-level risk remains moderate to low and results from this study should be confirmed in future adequately powered prospective studies, the high prevalence of adolescents consuming cannabis generates a large number of young people who could develop depression and suicidality attributable to cannabis.
Journal ArticleDOI
US Epidemiology of Cannabis Use and Associated Problems
TL;DR: An overview of the changing US epidemiology of cannabis use and associated problems suggests national increases in cannabis potency, prenatal and unintentional childhood exposure; and in adults, increased use, CUD, cannabis-related emergency room visits, and fatal vehicle crashes.
Journal ArticleDOI
Cannabis and cannabinoids for the treatment of people with chronic noncancer pain conditions: a systematic review and meta-analysis of controlled and observational studies.
Emily Stockings,Gabrielle Campbell,Wayne Hall,Suzanne Nielsen,Dino Zagic,Rakin Rahman,Bridin Murnion,Michael Farrell,Megan Weier,Louisa Degenhardt +9 more
TL;DR: It seems unlikely that cannabinoids are highly effective medicines for CNCP, as effects suggest that number needed to treat to benefit is high, and number neededto treat to harm is low, with limited impact on other domains.
Journal ArticleDOI
Cannabinoids for the treatment of mental disorders and symptoms of mental disorders: a systematic review and meta-analysis
Nicola Black,Emily Stockings,Gabrielle Campbell,Lucy Thi Tran,Dino Zagic,Wayne Hall,Michael Farrell,Louisa Degenhardt +7 more
TL;DR: There is scarce evidence to suggest that cannabinoids improve depressive disorders and symptoms, anxiety disorders, attention-deficit hyperactivity disorder, Tourette syndrome, post-traumatic stress disorder, or psychosis.
References
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Posted Content
Marijuana Use and High School Dropout: The Influence of Unobservables
TL;DR: Using a unique prospective panel study of over 4500 7th grade students from South Dakota who are followed through high school, propensity score weights are developed to adjust for baseline differences found to exist before marijuana initiation occurs for most students and it is found that time-varying parental and peer influences influence the likelihood of dropping out of school.
Journal ArticleDOI
Randomised, double-blind, placebo-controlled trial to assess the potential of cannabinoid receptor stimulation in the treatment of dystonia.
TL;DR: A double‐blind, randomised, placebo‐controlled, crossover study using the synthetic cannabinoid receptor agonist nabilone in patients with generalised and segmental primary dystonia showed no significant reduction in dystonIA following treatment with nabil one.