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The Health Effects of Cannabis and Cannabinoids: The Current State of Evidence and Recommendations for Research

Eric Groce
- Vol. 104, Iss: 4, pp 32-32
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TLDR
Despite increased cannabis use and a changing state-level policy landscape, conclusive evidence regarding the shortand long-term health effects—both harms and benefits—of cannabis use remains elusive.
Abstract
Recent years have seen a rapid rise in the medical and recreational use of cannabis: a broad term that can be used to describe the various products and chemical compounds (e.g., marijuana, cannabinoids) derived from different species of the cannabis plant. Despite increased cannabis use and a changing state-level policy landscape, conclusive evidence regarding the shortand long-term health effects—both harms and benefits—of cannabis use remains elusive.

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Citations
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The Association Between Cannabis Use and Aberrant Behaviors During Chronic Opioid Therapy for Chronic Pain.

TL;DR: Conurrent use of cannabis and opioids by patients with chronic pain appears to indicate higher risk for opioid misuse, and closer monitoring for opioid-related aberrancy is indicated for this group of patients.
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Head in the clouds? Cannabis users' creativity in new venture ideation depends on their entrepreneurial passion and experience

TL;DR: In this article, the authors explored differences between cannabis users' and non-users' creativity in new venture ideation by assessing the originality and feasibility of their ideas and found that cannabis users generate new venture ideas that are more original, but less feasible, compared to nonusers.
Journal ArticleDOI

Altered Corticolimbic Control of the Nucleus Accumbens by Long-term Δ9-Tetrahydrocannabinol Exposure.

TL;DR: Long-term exposure to Δ9-THC weakens prefrontal cortex glutamate input to the NAc shell and strengthens input from basolateral amygdala and ventral hippocampus, likely contributing to cognitive and psychiatric dysfunction that is associated with cannabis use.
Journal ArticleDOI

Changes in cannabis use, exposure, and health perceptions following legalization of adult recreational cannabis use in California: a prospective observational study

TL;DR: In a 6-month prospective observational study, this paper examined changes in adult cannabis use patterns and health perceptions following broadened legalization of cannabis use from medical to recreational purposes in California Respondents were part of Stanford University's WELL for Life registry, an online adult cohort concentrated in Northern California.
Journal ArticleDOI

Prenatal drug exposure and neurodevelopmental programming of glucocorticoid signalling.

TL;DR: A discussion of GC signalling and the HPA axis is presented, as well as the effects of prenatal drug exposure on these pathways and the stress response, and the interactions between GC and EC signalling in the developing brain and potential for neurodevelopmental consequences are explored.
References
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Journal ArticleDOI

Diagnostic and Statistical Manual of Mental Disorders

TL;DR: An issue concerning the criteria for tic disorders is highlighted, and how this might affect classification of dyskinesias in psychotic spectrum disorders.
Journal ArticleDOI

Systematic Review: Process of Forming Academic Service Partnerships to Reform Clinical Education

TL;DR: This study’s findings can provide practical guidelines to steer partnership programs within the academic and clinical bodies, with the aim of providing a collaborative partnership approach to clinical education.

The Newcastle-Ottawa Scale (NOS) for Assessing the Quality of Nonrandomised Studies in Meta-Analyses

TL;DR: The Newcastle-Ottawa Scale (NOS) as discussed by the authors was developed to assess the quality of nonrandomised studies with its design, content and ease of use directed to the task of incorporating the quality assessments in the interpretation of meta-analytic results.
Journal ArticleDOI

Cannabis use and risk of psychotic or affective mental health outcomes: a systematic review

TL;DR: There is now sufficient evidence to warn young people that using cannabis could increase their risk of developing a psychotic illness later in life, although evidence for affective outcomes is less strong.
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