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Journal ArticleDOI

Ti based biomaterials, the ultimate choice for orthopaedic implants – A review

TLDR
In this paper, the influence of alloy chemistry, thermomechanical processing and surface condition on these properties is discussed and various surface modification techniques to achieve superior biocompatibility, higher wear and corrosion resistance.
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This article is published in Progress in Materials Science.The article was published on 2009-05-01. It has received 4113 citations till now. The article focuses on the topics: Biomaterial.

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Surface guidance of stem cell behavior: Chemically tailored co-presentation of integrin-binding peptides stimulates osteogenic differentiation in vitro and bone formation in vivo.

TL;DR: It is demonstrated that, by rationally designing ligands, stem cell response can be efficiently guided towards the osteogenic phenotype and covalently graft to titanium a double branched molecule to guide stem cell fate in vitro and generate an osseoinductive titanium surface in vivo.
Journal ArticleDOI

In vitro degradation behavior and cytocompatibility of biodegradable AZ31 alloy with PEO/HT composite coating.

TL;DR: The results show that the PEO/HT composite coating is promising as protective coating on biodegradable magnesium-based implants to enhance their corrosion resistance as well as improve their surface cytocompatibility for orthopedic applications.
Journal ArticleDOI

Mechanical properties and microstructure of Ti-Mn alloys produced via powder metallurgy for biomedical applications.

TL;DR: Forged Ti-5Mn exhibits a good balance of mechanical properties such as ultimate tensile strength, elongation and Vickers hardness and the purely elastic properties of the Ti-10Mn alloy is attributed to the effects of the omega (ω) phase.
Journal ArticleDOI

Predominant factor determining wear properties of β-type and (α+β)-type titanium alloys in metal-to-metal contact for biomedical applications.

TL;DR: The predominant factor determining the wear properties of a new titanium alloy, Ti-29Nb-13Ta-4.6Zr (TNTZ) and a conventional titanium alloy), Ti-6Al-4V extra-low interstitial (Ti64, was investigated for TNTZ and Ti64 combinations in metal-to-metal contacting bio-implant applications.
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Enhancement in Sustained Release of Antimicrobial Peptide from Dual-Diameter-Structured TiO2 Nanotubes for Long-Lasting Antibacterial Activity and Cytocompatibility.

TL;DR: The resultant 35 nm capped dual-diameter nanotube film exhibited significant short- and long-term antibacterial activity not only against planktonic bacteria, but also against adhered bacteria, which is ascribed to the AMP-derived killing efficacy and the nanocaps-derived adhesion resistance.
References
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Journal ArticleDOI

Projections of primary and revision hip and knee arthroplasty in the United States from 2005 to 2030.

TL;DR: These large projected increases in demand for total hip and knee arthroplasties provide a quantitative basis for future policy decisions related to the numbers of orthopaedic surgeons needed to perform these procedures and the deployment of appropriate resources to serve this need.
Journal ArticleDOI

Titanium alloys in total joint replacement—a materials science perspective

TL;DR: This review examines current information on the physical and mechanical characteristics of titanium alloys used in artifical joint replacement prostheses, with a special focus on those issues associated with the long-term prosthetic requirements, e.g., fatigue and wear.
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Surface modification of titanium, titanium alloys, and related materials for biomedical applications

TL;DR: A review of surface modification techniques for titanium and titanium alloys can be found in this article, where the authors have shown that the wear resistance, corrosion resistance, and biological properties can be improved selectively using the appropriate surface treatment techniques while the desirable bulk attributes of the materials are retained.
Book

Principles and prevention of corrosion

Denny A Jones
TL;DR: In this article, the technology and evaluation of Corrosion is presented, with a focus on the effects of Metallurgical Structure on Corrosions, and a discussion of materials selection and design.
Journal ArticleDOI

On the mechanisms of biocompatibility.

David F. Williams
- 01 Jul 2008 - 
TL;DR: It is shown that, in the vast majority of circumstances, the sole requirement for biocompatibility in a medical device intended for long-term contact with the tissues of the human body is that the material shall do no harm to those tissues, achieved through chemical and biological inertness.
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