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Journal ArticleDOI

Ti based biomaterials, the ultimate choice for orthopaedic implants – A review

TLDR
In this paper, the influence of alloy chemistry, thermomechanical processing and surface condition on these properties is discussed and various surface modification techniques to achieve superior biocompatibility, higher wear and corrosion resistance.
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This article is published in Progress in Materials Science.The article was published on 2009-05-01. It has received 4113 citations till now. The article focuses on the topics: Biomaterial.

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Citations
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Perspectives on Titanium Science and Technology

TL;DR: In this paper, the complexity and variety of fundamental phenomena in this material system with a focus on phase transformations and mechanical behaviour are discussed. And the challenges that lie ahead in achieving these goals are delineated.
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Metallic implant biomaterials

TL;DR: In this article, the most critical challenges for metallic implant biomaterials are summarized, with emphasis on the most promising approaches and strategies, and the properties that affect biocompatibility and mechanical integrity are discussed in detail.
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Review on titanium and titanium based alloys as biomaterials for orthopaedic applications.

TL;DR: Various attempts to improve upon these properties like different processing routes, surface modifications have been inculcated in the paper to provide an insight into the extent of research and effort that has been put into developing a highly superior titanium orthopaedic implant.
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New Developments of Ti-Based Alloys for Biomedical Applications

TL;DR: Efforts have been made to reveal the latest scenario of bulk and porous Ti-based materials for biomedical applications, emphasizing their current status, future opportunities and obstacles for expanded applications.
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Mussel-Inspired Polydopamine Coating as a Universal Route to Hydroxyapatite Crystallization

TL;DR: A universal biomineralization route, called polydopamine‐assisted hydroxyapatite formation (pHAF), that can be applied to virtually any type and morphology of scaffold materials is demonstrated and can be an innovative foundation for future tissue engineering.
References
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Thermal and chemical modification of titanium-aluminum-vanadium implant materials: effects on surface properties, glycoprotein adsorption, and MG63 cell attachment.

TL;DR: It would also appear that the thermal treatment-induced enhancement of cell adhesion in the presence of this integrin-binding protein is due to its increased biological activity, rather than a mass effect alone, that appear to be associated with changes in chemical composition of the metallic surface.
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High strength, low stiffness, porous NiTi with superelastic properties

TL;DR: The unique combination of low stiffness, high strength, high recoverable strains and large energy absorption of porous superelastic Ni Ti, together with the known biocompatibility of NiTi, makes this material attractive for bone-implant applications.
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Influence of titanium surfaces on attachment of osteoblast-like cells in vitro.

TL;DR: grooved surfaces offered better cell attachment and proliferation than the other rough surfaces studied, and displayed a strong labelling for fibronectin at the cytoplasmic extensions coupled with intense osteonectin expression in comparison to the rough surfaced implants.
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Phase transformations in Ti-Nb-Ta and Ti-Nb-Ta-Zr alloys

TL;DR: In this paper, phase transformations in solution treated and quenched Ti-(13-26) Nb-(22-38) Ta (wt.%) and Ti(13-35.5) nb-(5-22) Ta-(4-7.2) Zr alloys have been studied.
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