Toxicological Evaluations of Rare Earths and Their Health Impacts to Workers: A Literature Review
TLDR
It is important to review the toxicological studies to improve the current understanding of the RE compounds in the field of occupational health to establish a sustainable, safe and healthy working environment for RE industries.Abstract:
In concert with the development of new materials in the last decade, the need for toxicological studies of these materials has been increasing. These new materials include a group of rare earths (RE). The use of RE nanotechnology is being considered in some green applications, to increase their efficiency by using nano-sized RE compounds, and therefore hazard evaluation and risk assessment are highly recommended. This review was conducted through an extensive contemplation of the literatures in toxicology with in vitro and in vivo studies. Major aspects reviewed were the toxicological evaluations of these elements and metallic compounds at the molecular and cellular level, animal and human epidemiological studies and environmental and occupational health impacts on workers. We also discuss the future prospect of industries with appliances using RE together with the significance of preventive efforts for workers’ health. To establish a safe and healthy working environment for RE industries, the use of biomarkers is increasing to provide sustainable measure, due to demand for information about the health risks from unfavorable exposures. Given the recent toxicological results on the exposure of cells, animals and workers to RE compounds, it is important to review the toxicological studies to improve the current understanding of the RE compounds in the field of occupational health. This will help to establish a sustainable, safe and healthy working environment for RE industries.read more
Citations
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Combined omics approaches reveal distinct responses between light and heavy rare earth elements in Saccharomyces cerevisiae
Nicolas Grosjean,Marie Le Jean,Jean Armengaud,Adam Schikora,Michel Chalot,Michel Chalot,Elisabeth M. Gross,Damien Blaudez +7 more
TL;DR: In this paper, transcriptomic and proteomic approaches were combined to decipher the molecular responses of the model organism Saccharomyces cerevisiae to light (LREE) and heavy (HREEs) rare earth elements.
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Biological monitoring of exposure to rare earth elements and selected metals in the inuit population of Nunavik, Canada
Ciprian Mihai Cirtiu,Mathieu Valcke,Michelle Gagné,Marie-Hélène Bourgault,Céline Narame,Souleymane Gadio,Patrick Poulin,Pierre Ayotte +7 more
TL;DR: In this article, the baseline biological exposure of the population to these elements, before potential mining development occurs, was determined by using ICP-MS platforms to quantify urinary concentrations of 17 rare earth elements and 7 elements of interest in Nunavik (arsenic, antimony, chromium, cobalt, nickel, thallium and uranium).
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Biodegradable Zn-Dy binary alloys with high strength, ductility, cytocompatibility, and antibacterial ability for bone-implant applications.
X.-P. Tong,Yue Han,R. Zhou,Wanying Jiang,Li Zhu,Yuncang Li,Shengbin Huang,Jianfeng Ma,Cuie Wen,Jixing Lin +9 more
TL;DR: In this article , the authors report the development of Zn-xDy (x = 1, 3, and 5 wt.%) alloys with high strength, ductility, cytocompatibility, antibacterial ability, and appropriate degradation rate for biodegradable bone-implant applications.
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Transmission Mechanism of Stock Price Fluctuation in the Rare Earth Industry Chain
TL;DR: In this paper, the authors used the time series of daily closing prices of stocks in the global rare earth industry chain in the past ten years as the research object and used the Granger causality test and complex network theory to construct the risk transmission network of the industrial chain.
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A 1D Cd-coordination polymer containing serine derivative and its application in luminescence sensor for Tb(Ⅲ)
TL;DR: In this paper , a chiral Cd-coordination polymer (CP1) was synthesized by solvothermal reaction with chiral ligand 1,4-bis((L −serine)methyl)benzene (L-H2bsmb) and cadmium oxide, and the structure of CP1 was characterized by single-crystal X-ray diffraction, fourier transform infrared spectoscopy (FT-IR).
References
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Rare earth nanoparticles prevent retinal degeneration induced by intracellular peroxides
TL;DR: The data indicate that the nanoceria particles may be effective in inhibiting the progression of ROI-induced cell death, which is thought to be involved in macular degeneration, retinitis pigmentosa and other blinding diseases, as well as the ROi-induced death of other cell types in diabetes, Alzheimer's disease, atherosclerosis, stroke and so on.
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Anti‐inflammatory Properties of Cerium Oxide Nanoparticles
Suzanne M. Hirst,Ajay S. Karakoti,Ron Tyler,Nammalwar Sriranganathan,Sudipta Seal,Christopher M. Reilly +5 more
TL;DR: It is suggested that cerium oxide nanoparticles are well tolerated in mice and are incorporated into cellular tissues and therefore serve as a novel therapy for chronic inflammation.
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Toxicity of Cerium Oxide Nanoparticles in Human Lung Cancer Cells
TL;DR: The cytotoxicity and oxidative stress caused by 20-nm cerium oxide (CeO2) nanoparticles in cultured human lung cancer cells was investigated and it was concluded that free radicals generated by exposure to 3.5 to 23.3 μg/ml CeO2 nanoparticles produce significant oxidative stress in the cells.
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Evaluation of short-term effects of rare earth and other elements used in magnesium alloys on primary cells and cell lines
Frank Feyerabend,Janine Fischer,Jakob Holtz,Frank Witte,Frank Witte,Regine Willumeit,Heiko Drücker,Carla Vogt,Norbert Hort +8 more
TL;DR: Of the elements with high solubility in magnesium alloys, Gd and Dy seem to be more suitable than Y, and La and Ce showed the highest cytotoxicity of the analysed elements.
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Exposure, health and ecological effects review of engineered nanoscale cerium and cerium oxide associated with its use as a fuel additive.
Flemming R. Cassee,Erna C. van Balen,Charanjeet Singh,David C. Green,Hans Muijser,Jason P. Weinstein,Kevin L. Dreher +6 more
TL;DR: There is an absolute critical need for integrated exposure and toxicological studies in order to accurately assess the environmental, ecological and health implications of nanotechnology enabled diesel fuel additives with existing as well as new engine designs and fuel formulations.
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