Journal ArticleDOI
Viper venom-induced inflammation and inhibition of free radical formation by pure compound (2-hydroxy-4-methoxy benzoic acid) isolated and purified from anantamul (Hemidesmus indicus R.Br) root extract
M.I. Alam,Aparna Gomes +1 more
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TLDR
The present investigation explored the possible venom neutralizing effect of a pure compound isolated and purified from the methanolic root extract of Hemidesmus indicus R.Rr.About:
This article is published in Toxicon.The article was published on 1998-01-01. It has received 112 citations till now. The article focuses on the topics: Hemidesmus indicus.read more
Citations
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Profile of medicinal plants with anti - ophidian property
TL;DR: Traditional, ethno botanical and pharmacological review of certain plants utilized in the cases of snakebite and randomness or the use of a variety of species in different families appears to be a feature of traditional snake bite treatments.
Journal ArticleDOI
Hemidesmus indicus L. Br.: critical assessment of in vitro biotechnological advancements and perspectives
TL;DR: The assessment of applicability of different methodologies in this aspect will aid in the selection of high-yielding germplasms or chemotypes which is not only profitable for industrial application but also important for basic and applied preclinical and clinical research studies.
Journal ArticleDOI
The potential of phenolic acids in therapy against snakebites: A review
TL;DR: The use of plant-derived compounds to inhibit the effects caused by snake venoms has been the object of a number of studies in recent years as discussed by the authors , and structural analyses indicate that the acids interact with important sites responsible for the action of toxins.
Journal ArticleDOI
Moringa oleifera Extract Extenuates Echis ocellatus Venom-Induced Toxicities, Histopathological Impairments and Inflammation via Enhancement of Nrf2 Expression in Rats
Akindele Oluwatosin Adeyi,Sodiq O. Adeyemi,Enoh-Obong P. Effiong,Babafemi Siji Ajisebiola,Olubisi E. Adeyi,Adewale Segun James +5 more
TL;DR: The findings substantiate the effectiveness of MOE as a potential remedy against E. ocellatus venom toxicities and abolish Lesions noticed on tissues of vital organs of untreated rats were abolished by MOE.
Journal ArticleDOI
Catechin and epicatechin as an adjuvant in the therapy of hemostasis disorders induced by snake venoms.
TL;DR: Catechin and epicatechin showed promising inhibitory action on proteases and phospholipases A2 and can be explored as an adjuvant for serum therapy or pharmaceutical purposes, once they act on homologous enzymes that are present in humans.
References
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Journal ArticleDOI
Superoxide dismutase: Improved assays and an assay applicable to acrylamide gels☆
TL;DR: The staining procedure for localizing superoxide dismutase on polyacrylamide electrophoretograms has been applied to extracts obtained from a variety of sources and could thus be assayed either in crude extracts or in purified protein fractions.
Journal ArticleDOI
A colorimetric method for the determination of serum glutamic oxalacetic and glutamic pyruvic transaminases.
Stanley Reitman,Sam Frankel +1 more
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Flavonoids, a class of natural products of high pharmacological potency
TL;DR: The few existing reports on the careful pharmacodynamic, pharmacokinetic and clinical studies which have been made have been summarized to provide a basis for a full-scale investigation of the therapeutic potential of flavonoids.
Journal ArticleDOI
Anti-inflammatory steroids induce biosynthesis of a phospholipase A2 inhibitor which prevents prostaglandin generation.
R J Flower,G J Blackwell +1 more
TL;DR: It is shown that similar events occur in the guinea pig perfused lung before inhibition by steroids of phospholipase A2 activity (and thus TXA2 generation), and a steroid-induced factor is discovered which mimics the anti-phospholipases effects of these anti-inflammatory agents.
Related Papers (5)
Snake venom neutralization by Indian medicinal plants (Vitex negundo and Emblica officinalis ) root extracts
M.I. Alam,Aparna Gomes +1 more
Development of simple standard assay procedures for the characterization of snake venom.
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