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World malaria report
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The article was published on 2005-01-01 and is currently open access. It has received 5145 citations till now. The article focuses on the topics: Malaria & Indoor residual spraying.read more
Citations
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Electrochemical POC device for fast malaria quantitative diagnosis in whole blood by using magnetic beads, Poly-HRP and microfluidic paper electrodes.
Gisela Ruiz-Vega,Kevin Arias-Alpízar,Erica de la Serna,Lívia Neves Borgheti-Cardoso,Elena Sulleiro,Israel Molina,Xavier Fernàndez-Busquets,Adrián Sánchez-Montalvá,F. Javier del Campo,Eva Baldrich +9 more
TL;DR: An electrochemical point-of-care device for the fast, simple and quantitative detection of Plasmodiumfalciparum lactate dehydrogenase (PfLDH) in whole blood samples is reported.
Journal ArticleDOI
Structural delineation of potent transmission-blocking epitope I on malaria antigen Pfs48/45.
P. Kundu,A. Semesi,Matthijs M. Jore,Merribeth J. Morin,V.L. Price,A. Liang,J. Li,Kazutoyo Miura,Robert W. Sauerwein,C.R. King,Jean-Philippe Julien +10 more
TL;DR: This work reveals how the Pfs48/45 6C domain adopts a (SAG1)-related-sequence (SRS) fold and structurally delineates potent epitope I and shows how mAb 85RF45.1 recognizes an electronegative surface with nanomolar affinity.
Journal ArticleDOI
Fragment-Based Screening of a Natural Product Library against 62 Potential Malaria Drug Targets Employing Native Mass Spectrometry.
Hoan Vu,Liliana Pedro,Tin Mak,B. P. McCormick,Jessica Rowley,Miaomiao Liu,Angela Di Capua,Billy J Williams-Noonan,Ngoc B. Pham,Rebecca H. Pouwer,Bao Nguyen,Katherine T. Andrews,Tina S. Skinner-Adams,Jessica E. Kim,Wim G. J. Hol,Raymond Hui,Gregory J. Crowther,Wesley C. Van Voorhis,Ronald J. Quinn +18 more
TL;DR: 96 low-molecular-weight natural products are identified as binding partners of 32 of the putative malarial targets and 79 fragments have direct growth inhibition on Plasmodium falciparum at concentrations that are promising for the development of fragment hits against these protein targets.
Journal ArticleDOI
Quality of malaria case management in Malawi: Results from a nationally representative health facility survey
Laura C. Steinhardt,Jobiba Chinkhumba,Adam Wolkon,Madalitso Luka,Misheck Luhanga,John Sande,Jessica Oyugi,Doreen Ali,Don P. Mathanga,Jacek Skarbinski +9 more
TL;DR: Malawi has a high burden of uncomplicated malaria but nearly one-third of all patients receive incorrect malaria treatment, including under- and over-treatment.
Journal ArticleDOI
Disparities of Plasmodium falciparum infection, malaria-related morbidity and access to malaria prevention and treatment among school-aged children: a national cross-sectional survey in Côte d'Ivoire.
Clarisse A. Houngbedji,Prisca B. N’Dri,Eveline Hürlimann,Eveline Hürlimann,Richard B. Yapi,Kigbafori D. Silué,Gotianwa Soro,Benjamin G. Koudou,Benjamin G. Koudou,Cinthia A. Acka,Serge-Brice Assi,Penelope Vounatsou,Penelope Vounatsou,Eliézer K. N’Goran,Agathe Fantodji,Jürg Utzinger,Jürg Utzinger,Giovanna Raso,Giovanna Raso +18 more
TL;DR: Seven out of ten school-aged children in Côte d’Ivoire are infected with P. falciparum and malaria-related morbidity is considerable, and this study points out that bed net usage is quite low and there are important inequalities in preventive measures and treatment.
References
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The Analysis and Display of Real Time Surface Climate Data
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Malaria mortality rates in South Asia and in Africa: implications for malaria control.
TL;DR: This work examines malaria-related mortality under different circumstances and discusses implications for the management of malaria in these settings and emphasizes the power of rapid case treatment to save lives at risk under virtually all circumstances of malaria transmission.
Journal Article
Epidemiology of malaria in displaced Khmers on the Thai-Kampuchean border.
TL;DR: Malaria epidemiology from 1983 to 1985 in displaced Khmers living in camps on the Thai-Kampuchean border was studied and Epidemiological information has been more useful for planning than for evaluating control measures.
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