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World malaria report
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The article was published on 2005-01-01 and is currently open access. It has received 5145 citations till now. The article focuses on the topics: Malaria & Indoor residual spraying.read more
Citations
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Insecticide Resistance in African Anopheles Mosquitoes: A Worsening Situation that Needs Urgent Action to Maintain Malaria Control
Hilary Ranson,Natalie Lissenden +1 more
TL;DR: An update is provided on the current status of resistance to the major insecticide classes in African malaria vectors, the evidence that this resistance is already compromising malaria control efforts is considered, and some of the new insecticide-based tools under development and the challenges in ensuring they are most effectively deployed to manage resistance are highlighted.
Journal ArticleDOI
A research agenda to underpin malaria eradication.
Pedro L. Alonso,Graham Brown,Myriam Arévalo-Herrera,Fred Binka,Chetan E. Chitnis,Frank H. Collins,Ogobara K. Doumbo,Brian Greenwood,B. Fenton Hall,Myron M. Levine,Kamini Mendis,Robert D. Newman,Christopher V. Plowe,Mario Henry Rodriguez,Robert E. Sinden,Laurence Slutsker,Marcel Tanner +16 more
TL;DR: The Malaria Eradication Research Agenda initiative and the set of articles published in this PLoS Medicine Supplement that distill the research questions key to malaria eradication are introduced.
Journal ArticleDOI
K13-propeller mutations confer artemisinin resistance in Plasmodium falciparum clinical isolates
Judith Straimer,Nina F. Gnädig,Benoit Witkowski,Chanaki Amaratunga,Valentine Duru,Arba Pramundita Ramadani,Arba Pramundita Ramadani,Mélanie Dacheux,Nimol Khim,Lei Zhang,Stephen Lam,Philip D. Gregory,Fyodor D. Urnov,Odile Mercereau-Puijalon,Françoise Benoit-Vical,Françoise Benoit-Vical,Rick M. Fairhurst,Didier Menard,David A. Fidock +18 more
TL;DR: The data provide a conclusive rationale for worldwide K13-propeller sequencing to identify and eliminate artemisinin-resistant parasites and imperils efforts to reduce the global malaria burden.
Journal ArticleDOI
A Genome-wide CRISPR Screen in Toxoplasma Identifies Essential Apicomplexan Genes.
Saima M. Sidik,Diego Huet,Suresh M. Ganesan,My Hang Huynh,Timothy C. Wang,Timothy C. Wang,Armiyaw S. Nasamu,Prathapan Thiru,Jeroen P. J. Saeij,Vern B. Carruthers,Jacquin C. Niles,Sebastian Lourido +11 more
TL;DR: In this article, the authors adapted CRISPR/Cas9 to assess the contribution of each gene from the parasite Toxoplasma gondii during infection of human fibroblasts.
Journal ArticleDOI
Generation of Political Priority for Global Health Initiatives: A Framework and Case Study of Maternal Mortality
TL;DR: A framework consisting of four categories: the strength of the actors involved in the initiative, the power of the ideas they use to portray the issue, the nature of the political contexts in which they operate, and characteristics of the issue itself is proposed for a global initiative to reduce maternal mortality.
References
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The Analysis and Display of Real Time Surface Climate Data
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Malaria mortality rates in South Asia and in Africa: implications for malaria control.
TL;DR: This work examines malaria-related mortality under different circumstances and discusses implications for the management of malaria in these settings and emphasizes the power of rapid case treatment to save lives at risk under virtually all circumstances of malaria transmission.
Journal Article
Epidemiology of malaria in displaced Khmers on the Thai-Kampuchean border.
TL;DR: Malaria epidemiology from 1983 to 1985 in displaced Khmers living in camps on the Thai-Kampuchean border was studied and Epidemiological information has been more useful for planning than for evaluating control measures.
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