A
Adam R. Wespiser
Researcher at University of Massachusetts Medical School
Publications - 6
Citations - 574
Adam R. Wespiser is an academic researcher from University of Massachusetts Medical School. The author has contributed to research in topics: Population & Innate immune system. The author has an hindex of 5, co-authored 5 publications receiving 468 citations.
Papers
More filters
Journal ArticleDOI
Genomic insights into the Ixodes scapularis tick vector of Lyme disease
Monika Gulia-Nuss,Monika Gulia-Nuss,Andrew B. Nuss,Andrew B. Nuss,Jason M. Meyer,Jason M. Meyer,Daniel E. Sonenshine,R. Michael Roe,Robert M. Waterhouse,David B. Sattelle,José de la Fuente,José de la Fuente,José M. C. Ribeiro,Karyn Megy,Karyn Megy,Jyothi Thimmapuram,Jason R. Miller,Brian P. Walenz,Brian P. Walenz,Sergey Koren,Sergey Koren,Jessica B. Hostetler,Jessica B. Hostetler,Mathangi Thiagarajan,Mathangi Thiagarajan,Vinita Joardar,Vinita Joardar,Linda Hannick,Linda Hannick,Shelby L. Bidwell,Shelby L. Bidwell,Martin Hammond,Sarah Young,Qiandong Zeng,Jenica L. Abrudan,Jenica L. Abrudan,Francisca C. Almeida,Nieves Ayllón,Ketaki Bhide,Brooke W. Bissinger,Elena Bonzón-Kulichenko,Steven D. Buckingham,Daniel R. Caffrey,Melissa J. Caimano,Vincent Croset,Vincent Croset,Timothy P. Driscoll,Timothy P. Driscoll,Don Gilbert,Joseph J. Gillespie,Joseph J. Gillespie,Gloria I. Giraldo-Calderón,Gloria I. Giraldo-Calderón,Jeffrey M. Grabowski,Jeffrey M. Grabowski,David Jiang,Sayed M.S. Khalil,Donghun Kim,Donghun Kim,Katherine M. Kocan,Juraj Koči,Juraj Koči,Richard J. Kuhn,Timothy J. Kurtti,Kristin Lees,Kristin Lees,Emma G. Lang,Ryan C. Kennedy,Hyeogsun Kwon,Hyeogsun Kwon,Rushika Perera,Rushika Perera,Yumin Qi,Justin D. Radolf,Joyce M. Sakamoto,Alejandro Sánchez-Gracia,Maiara S. Severo,Maiara S. Severo,Neal S. Silverman,Ladislav Šimo,Ladislav Šimo,Marta Tojo,Marta Tojo,Cristian Tornador,Janice P. Van Zee,Jesús Vázquez,Filipe G. Vieira,Margarita Villar,Adam R. Wespiser,Yunlong Yang,Jiwei Zhu,Peter Arensburger,Patricia V. Pietrantonio,Stephen C. Barker,Renfu Shao,Evgeny M. Zdobnov,Evgeny M. Zdobnov,Frank Hauser,Cornelis J. P. Grimmelikhuijzen,Yoonseong Park,Julio Rozas,Richard Benton,Joao H. F. Pedra,Joao H. F. Pedra,David R. Nelson,Maria F. Unger,Jose M. C. Tubio,Jose M. C. Tubio,Zhijian Jake Tu,Hugh M. Robertson,Martin Shumway,Martin Shumway,Granger G. Sutton,Jennifer R. Wortman,Daniel Lawson,Stephen K. Wikel,Vishvanath Nene,Vishvanath Nene,Claire M. Fraser,Frank H. Collins,Bruce W. Birren,Karen E. Nelson,Elisabet Caler,Elisabet Caler,Catherine A. Hill +124 more
TL;DR: Insights from genome analyses into parasitic processes unique to ticks, including host ‘questing', prolonged feeding, cuticle synthesis, blood meal concentration, novel methods of haemoglobin digestion, haem detoxification, vitellogenesis and prolonged off-host survival are reported.
Journal ArticleDOI
The Genome of Anopheles darlingi , the main neotropical malaria vector
Osvaldo Marinotti,Gustavo C. Cerqueira,Luiz Gonzaga Paula de Almeida,Maria Inês Tiraboschi Ferro,Élgion Lúcio da Silva Loreto,Arnaldo Zaha,Santuza M. R. Teixeira,Adam R. Wespiser,Alexandre Almeida e Silva,Aline Daiane Schlindwein,Ana Carolina Landim Pacheco,Ana Carolina Landim Pacheco,Arthur Luiz da Costa da Silva,Brenton R. Graveley,Brian P. Walenz,Bruna de Araujo Lima,Carlos Alexandre Gomes Ribeiro,Carlos Gustavo Nunes-Silva,Carlos Roberto de Carvalho,Célia Maria de Almeida Soares,Cláudia Beatriz Afonso de Menezes,Cleverson Carlos Matiolli,Daniel R. Caffrey,Demetrius A. M. Araújo,Diana Oliveira,Douglas T. Golenbock,Edmundo C. Grisard,Fabiana Fantinatti-Garboggini,Fabíola Marques de Carvalho,Fernando Gomes Barcellos,Francisco Prosdocimi,Gemma E. May,Gilson Martins de Azevedo Júnior,Giselle Moura Guimarães,Gustavo H. Goldman,Itácio Q. M. Padilha,Jacqueline da Silva Batista,Jesus Aparecido Ferro,José M. C. Ribeiro,Juliana Lopes Rangel Fietto,Karina Maia Dabbas,Louise Cerdeira,Lucymara Fassarella Agnez-Lima,Marcelo Brocchi,Marcos Oliveira de Carvalho,Marcus de Melo Teixeira,Maria de Mascena Diniz Maia,Maria Helena S. Goldman,Maria Paula Cruz Schneider,Maria Sueli Soares Felipe,Maria Sueli Soares Felipe,Mariangela Hungria,Marisa Fabiana Nicolás,Maristela Pereira,Martín Alejandro Montes,Maurício Egídio Cantão,Michel Vincentz,Míriam Silva Rafael,Neal S. Silverman,Patrícia Hermes Stoco,Rangel C. Souza,Renato Vicentini,Ricardo T. Gazzinelli,Rogério de Oliveira Neves,Rosane Silva,Spartaco Astolfi-Filho,Talles Eduardo Ferreira Maciel,Turán P. Ürményi,Wanderli Pedro Tadei,Erney P. Camargo,Ana Tereza Ribeiro de Vasconcelos +70 more
TL;DR: The first effort to sequence the genome of a neotropical malaria vector, and open a new window through which we can contemplate the evolutionary history of anopheline mosquitoes, is presented in this article, which provides valuable information that may lead to novel strategies to reduce malaria transmission on the South American continent.
Journal ArticleDOI
RNA Helicase Signaling Is Critical for Type I Interferon Production and Protection against Rift Valley Fever Virus during Mucosal Challenge
Megan E. Ermler,Ekaterina Yerukhim,Jill Schriewer,Stefan A. Schattgen,Zachary Traylor,Adam R. Wespiser,Daniel R. Caffrey,Zhijian J. Chen,Charles H. King,Michael Gale,Marco Colonna,Katherine A. Fitzgerald,R. Mark L. Buller,Amy G. Hise +13 more
TL;DR: It is demonstrated here that RNA helicases are critical for IFN production by immune cells and that signaling through the helicase adaptor molecule MAVS (mitochondrial antiviral signaling) is protective against mortality and more subtle pathology during RVFV infection.
Journal ArticleDOI
The domain structure and distribution of Alu elements in long noncoding RNAs and mRNAs
TL;DR: The distribution and evolution of Alu elements in spliced transcripts are investigated to suggest that Alu-containing RNAs are capable of forming stable structures and that some of these Alu domains might have novel biological functions.
Journal ArticleDOI
Overexpression of Membrane-Bound Fas Ligand (CD95L) Exacerbates Autoimmune Disease and Renal Pathology in Pristane-Induced Lupus
Lukas Bossaller,Vijay A. K. Rathinam,Ramon G. Bonegio,Ping I. Chiang,Patricia Busto,Adam R. Wespiser,Daniel R. Caffrey,Quan Zhen Li,Chandra Mohan,Katherine A. Fitzgerald,Eicke Latz,Eicke Latz,Eicke Latz,Ann Marshak-Rothstein +13 more
TL;DR: It is demonstrated that FasL promotes inflammation in TMPD-induced autoimmunity, and its cleavage limits FasL proinflammatory activity.