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Adrian J. Wolstenholme

Researcher at University of Bath

Publications -  53
Citations -  4879

Adrian J. Wolstenholme is an academic researcher from University of Bath. The author has contributed to research in topics: Caenorhabditis elegans & Haemonchus contortus. The author has an hindex of 31, co-authored 51 publications receiving 4581 citations.

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Genome Sequence of the Pea Aphid Acyrthosiphon pisum

Stephen Richards, +223 more
- 01 Jan 2010 - 
TL;DR: The genome of the pea aphid shows remarkable levels of gene duplication and equally remarkable gene absences that shed light on aspects of aphid biology, most especially its symbiosis with Buchnera.
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Drug resistance in veterinary helminths

TL;DR: Some of the recent findings on resistance mechanisms are summarized, some recommendations for limiting its impact are put forward and some priorities for research in this area are suggested.
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Glutamate-gated chloride channels and the mode of action of the avermectin/milbemycin anthelmintics.

TL;DR: The known expression patterns of the GluCl explain most of the observed biological effects of treatment with the macrocyclic lactones, though the reason for the long-lasting inhibition of larval production in filarial species is still poorly understood.
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Characterisation of the binding of [3H]methyllycaconitine: a new radioligand for labelling α7-type neuronal nicotinic acetylcholine receptors

TL;DR: [3H]MLA, a norditerpenoid alkaloid isolated from Delphinium seeds, is a novel radiolabel for characterising alpha 7-type nAChR and provides advantages over the use of radiolabelled alpha bungarotoxin for rapid and accurate equilibrium binding assays.
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Human peripheral blood mononuclear cells express GABAA receptor subunits.

TL;DR: It is concluded that cells within the human PBMC population, including lymphocytes, express functional GABAA receptors and these receptors may modulate immune responses.