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Ajit Varki
Researcher at University of California, San Diego
Publications - 557
Citations - 63836
Ajit Varki is an academic researcher from University of California, San Diego. The author has contributed to research in topics: Sialic acid & SIGLEC. The author has an hindex of 124, co-authored 542 publications receiving 58772 citations. Previous affiliations of Ajit Varki include Emory University & National Institute of Advanced Industrial Science and Technology.
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Glycan-binding Proteins
Ajit Varki,Richard D. Cummings,Jeffrey D. Esko,Hudson H. Freeze,Pamela Stanley,Carolyn R. Bertozzi,Gerald W. Hart,Marilynn E. Etzler +7 more
Journal ArticleDOI
Sialoglycan-binding patterns of bacterial AB5 toxin B subunits correlate with host range and toxicity, indicating evolution independent of A subunits
Naazneen Khan,Aniruddha Sasmal,Zahra Khedri,Patrick Secrest,Andrea Verhagen,Saurabh Srivastava,Nissi Varki,Xin Chen,Hai-Tao Yu,Travis Clarke Beddoe,Adrienne W. Paton,James C. Paton,Ajit Varki +12 more
TL;DR: In this paper , a phylogenetic analysis of Y. pestis Sia-specific B5 pentamers was performed and the authors found that B subunit phylogeny evolved independently of B subunits and suggest a future B sub-unit nomenclature based on bacterial species names.
Posted ContentDOI
Development and applications of sialoglycan-recognizing probes (SGRPs) with defined specificities: exploring the dynamic mammalian sialoglycome
Saurabh Srivastava,Verhagen A,Aniruddha Sasmal,Brian R. Wasik,Diaz S,Hai Yu,Barbara A. Bensing,Naazneen Khan,Khedri Z,Secrest P,Paul M. Sullam,Nissi Varki,Xi Chen,Colin R. Parrish,Ajit Varki +14 more
TL;DR: In this article, the authors used a set of naturally-evolved microbial molecules (bacterial adhesins, toxin subunits and viral hemagglutinininesterases) that recognize sialoglycans with defined specificity to delineate 9 classes of Sialoglycan Recognizing Probes (SGRPs: SGRP1-SGRP9) that can be used to explore mammalian sialome changes in a simple and systematic manner.
Glycans in Acquired Human Diseases -- Essentials of Glycobiology
Ajit Varki,Richard D. Cummings,Jeffrey D. Esko,Hudson H. Freeze,Pamela Stanley,Carolyn R. Bertozzi,Gerald W. Hart,Marilynn E. Etzler +7 more