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Ajit Varki
Researcher at University of California, San Diego
Publications - 557
Citations - 63836
Ajit Varki is an academic researcher from University of California, San Diego. The author has contributed to research in topics: Sialic acid & SIGLEC. The author has an hindex of 124, co-authored 542 publications receiving 58772 citations. Previous affiliations of Ajit Varki include Emory University & National Institute of Advanced Industrial Science and Technology.
Papers
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Proteins That Bind Sulfated Glycosaminoglycans -- Essentials of Glycobiology
Ajit Varki,Richard D. Cummings,Jeffrey D. Esko,Hudson H. Freeze,Pamela Stanley,Carolyn R. Bertozzi,Gerald W. Hart,Marilynn E. Etzler +7 more
Journal ArticleDOI
Therapeutic CMP-Nonulosonates against Multidrug-Resistant Neisseria gonorrhoeae.
Sunita Gulati,Ian C. Schoenhofen,Theresa Lindhout-Djukic,Melissa J. Schur,Corinna S. Landig,Sudeshna Saha,Lingquan Deng,Lisa A. Lewis,Bo Zheng,Ajit Varki,Sanjay Ram +10 more
TL;DR: CMP-NulOs remain viable leads as topical preventive/therapeutic agents against the global threat of multidrug-resistant N. gonorrhoeae and CMP-Leg5,7Ac2 was the most pH and temperature stable.
Patent
Elimination of N-glycolylneuraminic acid from animal products for human use
TL;DR: In this article, a method to produce Neu5Gc-free animals and products therefrom comprising disrupting the CMAH gene and thereby reducing or eliminating Neu 5Gc from biological material of non-humans.
Patent
Elimination of a contaminating non-human sialic acid by metabolic competition
TL;DR: In this paper, the human sialic acid i\7-acetylneuraminic acid (Neu5Ac) in glycosidically-bound or free form, or its precursor N- acetylmannosamine (ManNAc) in an amount sufficient to metabolically compete out the Neu5Gc, either as it enters the cells for the first time or when it recycles from breakdown of preexisting cellular molecules.
Patent
Compositions and Methods for Detecting Cancer
TL;DR: In this article, a sialylated glycans and antibodies that specifically bind to them are used for early detection and diagnosis of cancer, which is useful for early diagnosis and early detection of cancer.