Debbie A Lawlor

TL;DR: In this article, the authors examined the association of body mass index (BMI) with future hospital admissions for psychoses or depression/anxiety disorders in a large prospective study of 7036 men and 8327 women.

TL;DR: Advice is provided on exploring and mitigating possible bias when genetic instrumental variables (IVs) associate with traits other than the exposure of interest in Mendelian randomization (MR) studies and the pros and cons of relying more on sensitivity analyses without considering particular pleiotropic paths versus systematically exploring and controlling for potential pleiotropy paths via known characteristics.

TL;DR: In this paper, the authors used a large two-sample Mendelian randomization (MR) design to assess for a causal relationship between plasma urate and Parkinson's disease risk.

TL;DR: GPs are enthusiastic about promoting physical activity for the management of depression and may do so without reference to an evidence base, but patients’ perceptions of physical activity as a treatment and their ability to engage with physical activity should be explored.

TL;DR: This work has used the gene‐centric Illumina HumanCVD BeadChip to identify common genetic determinants of Von Willebrand factor levels in healthy men and women.