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Debbie A Lawlor
Researcher at University of Bristol
Publications - 1118
Citations - 118183
Debbie A Lawlor is an academic researcher from University of Bristol. The author has contributed to research in topics: Population & Body mass index. The author has an hindex of 147, co-authored 1114 publications receiving 101123 citations. Previous affiliations of Debbie A Lawlor include Southampton General Hospital & University of Vermont.
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Journal ArticleDOI
Pregnancy Characteristics and Women's Future Cardiovascular Health: An Underused Opportunity to Improve Women's Health?
TL;DR: The findings of this review suggest consistent and often strong associations of pregnancy complications with latent and future cardiovascular disease and the utility of these prevalent pregnancy complications in identifying high-risk women for screening, prevention, and treatment of cardiovascular disease.
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Prevalence of elevated alanine aminotransferase among US adolescents and associated factors: NHANES 1999-2004.
TL;DR: AlT level is associated with waist circumference and insulin resistance even in a young population and could be utilized to identify adolescents who may benefit from screening for NAFLD, offering an opportunity to prevent disease progression at an early age.
Journal ArticleDOI
Common Variation in the FTO Gene Alters Diabetes-Related Metabolic Traits to the Extent Expected Given Its Effect on BMI
Rachel M. Freathy,Nicholas J. Timpson,Nicholas J. Timpson,Debbie A Lawlor,Anneli Pouta,Yoav Ben-Shlomo,Aimo Ruokonen,Shah Ebrahim,Beverley M. Shields,Eleftheria Zeggini,Michael N. Weedon,Cecilia M. Lindgren,Hana Lango,David Melzer,Luigi Ferrucci,Giuseppe Paolisso,Matt Neville,Fredrik Karpe,Colin N. A. Palmer,Andrew D. Morris,Paul Elliott,Marjo-Riitta Järvelin,George Davey Smith,Mark I. McCarthy,Andrew T. Hattersley,Timothy M. Frayling +25 more
TL;DR: FTO genotype is associated with metabolic traits to an extent entirely consistent with its effect on BMI, and the importance of using appropriately powered studies to assess the effects of a known diabetes or obesity variant on secondary traits correlated with these conditions is highlighted.
Journal ArticleDOI
New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism.
Momoko Horikoshi,Hanieh Yaghootkar,Dennis O. Mook-Kanamori,Dennis O. Mook-Kanamori,Ulla Sovio,Ulla Sovio,H. Rob Taal,Branwen J. Hennig,Jonathan P. Bradfield,Beate St Pourcain,David M. Evans,Pimphen Charoen,Pimphen Charoen,Marika Kaakinen,Diana L. Cousminer,Terho Lehtimäki,Eskil Kreiner-Møller,Nicole M. Warrington,Mariona Bustamante,Bjarke Feenstra,Diane J. Berry,Elisabeth Thiering,Thiemo Pfab,Thiemo Pfab,Sheila J. Barton,Beverley M. Shields,Marjan Kerkhof,Elisabeth M. van Leeuwen,Anthony J. C. Fulford,Zoltán Kutalik,Zoltán Kutalik,Jing Hua Zhao,Marcel den Hoed,Anubha Mahajan,Virpi Lindi,Liang Kee Goh,Jouke-Jan Hottenga,Ying Wu,Olli T. Raitakari,Marie Neergaard Harder,Aline Meirhaeghe,Aline Meirhaeghe,Aline Meirhaeghe,Ioanna Ntalla,Rany M. Salem,Rany M. Salem,Karen A. Jameson,Kaixin Zhou,Dorota Monies,Vasiliki Lagou,Mirna Kirin,Jani Heikkinen,Linda S. Adair,Fowzan S. Alkuraya,Ali Al-Odaib,Philippe Amouyel,Philippe Amouyel,Philippe Amouyel,Ehm A. Andersson,Amanda J. Bennett,Alexandra I. F. Blakemore,Jessica L. Buxton,Jean Dallongeville,Jean Dallongeville,Jean Dallongeville,Shikta Das,Eco J. C. de Geus,Xavier Estivill,Claudia Flexeder,Philippe Froguel,Philippe Froguel,Philippe Froguel,Frank Geller,Keith M. Godfrey,Keith M. Godfrey,Frédéric Gottrand,Christopher J. Groves,Torben Hansen,Torben Hansen,Joel N. Hirschhorn,Joel N. Hirschhorn,Albert Hofman,Mads V. Hollegaard,David M. Hougaard,Elina Hyppönen,Hazel Inskip,Aaron Isaacs,Aaron Isaacs,Torben Jørgensen,Christina Kanaka-Gantenbein,John P. Kemp,Wieland Kiess,Tuomas O. Kilpeläinen,Tuomas O. Kilpeläinen,Norman Klopp,Bridget A. Knight,Christopher W. Kuzawa,George McMahon,John P. Newnham,Harri Niinikoski,Ben A. Oostra,Louise Pedersen,Dirkje S. Postma,Susan M. Ring,Fernando Rivadeneira,Neil R. Robertson,Sylvain Sebert,Sylvain Sebert,Olli Simell,Torsten Slowinski,Carla M. T. Tiesler,Anke Tönjes,Allan Vaag,Allan Vaag,Jorma Viikari,Jacqueline M. Vink,Nadja Hawwa Vissing,Nicholas J. Wareham,Gonneke Willemsen,Daniel R. Witte,Haitao Zhang,Jianhua Zhao,James F. Wilson,Michael Stumvoll,Andrew M. Prentice,Brian F. Meyer,Ewan R. Pearson,Colin Boreham,Cyrus Cooper,Matthew W. Gillman,George Dedoussis,Luis A. Moreno,Oluf Pedersen,Oluf Pedersen,Oluf Pedersen,Maiju Saarinen,Karen L. Mohlke,Dorret I. Boomsma,Seang-Mei Saw,Seang-Mei Saw,Timo A. Lakka,Antje Körner,Ruth J. F. Loos,Ken K. Ong,Peter Vollenweider,Cornelia M. van Duijn,Gerard H. Koppelman,Andrew T. Hattersley,John W. Holloway,Berthold Hocher,Joachim Heinrich,Chris Power,Mads Melbye,Mònica Guxens,Craig E. Pennell,Klaus Bønnelykke,Hans Bisgaard,Johan G. Eriksson,Elisabeth Widen,Hakon Hakonarson,André G. Uitterlinden,Anneli Pouta,Anneli Pouta,Debbie A Lawlor,George Davey Smith,Timothy M. Frayling,Mark I. McCarthy,Mark I. McCarthy,Struan F.A. Grant,Vincent W. V. Jaddoe,Marjo-Riitta Järvelin,Nicholas J. Timpson,Inga Prokopenko,Rachel M. Freathy,Rachel M. Freathy +174 more
TL;DR: The number of loci associated at genome-wide significance to 7, accounting for a similar proportion of variance as maternal smoking, are extended and highlight genetic links between fetal growth and postnatal growth and metabolism.
Journal ArticleDOI
Mental health before and during the COVID-19 pandemic in two longitudinal UK population cohorts.
Alex S. F. Kwong,Rebecca M. Pearson,Mark Adams,Kate Northstone,Kate Tilling,Daniel J. Smith,Chloe Fawns-Ritchie,Helen Bould,Naomi Warne,Stanley Zammit,David Gunnell,Paul Moran,Nadia Micali,Abraham Reichenberg,Matthew Hickman,Dheeraj Rai,Simon Haworth,Archie Campbell,Drew Altschul,Robin Flaig,Andrew M. McIntosh,Debbie A Lawlor,David J. Porteous,Nicholas J. Timpson +23 more
TL;DR: In both studies, anxiety and depression during the pandemic was greater in younger members, women, those with pre-existing mental/physical health conditions and individuals in socioeconomic adversity, even when controlling for pre-pandemicxiety and depression.