Debbie A Lawlor

TL;DR: Alleles that predispose to higher metabolically favourable adult adiposity collectively have a stronger effect on birth weight than those predisposing to higher BMI, suggesting that the early accumulation of a metabolally favourable fat distribution might underlie part of the observed association between higher birth weight and higher adult BMI.

TL;DR: The scientometric analyses of original research output from these birth cohorts also paint a pessimistic landscape in Pakistan- where Pakistani sites for birth cohorts contributed only 31 publications; a majority of these utilized the MAL-ED birth cohort data.

TL;DR: It is suggested that males begin to have higher VLDL triglycerides in adolescence, and that this sex difference is larger at older ages; causal analyses of this and other traits are needed to understand whether they differentially affect CHD risk among males and females.

TL;DR: In this paper, the authors identify 290 genetic determinants of ovarian ageing, assessed using normal variation in age at natural menopause (ANM) in ∼200,000 women of European ancestry.

TL;DR: The results are consistent with evidence from randomized controlled trials that increased maternal folate levels increase offspring birthweight and did not find evidence for a causal effect of B12 on offspring birth Weight, suggesting previous observational studies may have been due to confounding.