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Debbie A Lawlor
Researcher at University of Bristol
Publications - 1118
Citations - 118183
Debbie A Lawlor is an academic researcher from University of Bristol. The author has contributed to research in topics: Population & Body mass index. The author has an hindex of 147, co-authored 1114 publications receiving 101123 citations. Previous affiliations of Debbie A Lawlor include Southampton General Hospital & University of Vermont.
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Journal ArticleDOI
Does High C-reactive Protein Concentration Increase Atherosclerosis? The Whitehall II Study
Mika Kivimäki,Debbie A Lawlor,George Davey Smith,Meena Kumari,Ann E. Donald,Ann E. Donald,Annie Britton,Juan P. Casas,Tina Shah,Eric J. Brunner,Nicholas J. Timpson,Julian Halcox,Michelle A. Miller,Steve E. Humphries,John E. Deanfield,John E. Deanfield,Michael Marmot,Aroon D. Hingorani +17 more
TL;DR: Both multivariable standard regression analysis and Mendelian randomization analysis suggest that the association of CRP with carotid atheroma indexed by CIMT may not be causal.
Journal ArticleDOI
Genetic Evidence for Causal Relationships Between Maternal Obesity-Related Traits and Birth Weight
Jessica Tyrrell,Jessica Tyrrell,Rebecca C Richmond,Rebecca C Richmond,Tom Palmer,Tom Palmer,Bjarke Feenstra,Janani Rangarajan,Sarah Metrustry,Alana Cavadino,Alana Cavadino,Lavinia Paternoster,Loren L. Armstrong,N. Maneka G. De Silva,Andrew R. Wood,Momoko Horikoshi,Momoko Horikoshi,Frank Geller,Ronny Myhre,Jonathan P. Bradfield,Eskil Kreiner-Møller,Ville Huikari,Jodie N. Painter,Jouke-Jan Hottenga,Jouke-Jan Hottenga,Catherine Allard,Catherine Allard,Diane J. Berry,Luigi Bouchard,Luigi Bouchard,Shikta Das,David M. Evans,David M. Evans,Hakon Hakonarson,Hakon Hakonarson,M. Geoffrey Hayes,Jani Heikkinen,Albert Hofman,Albert Hofman,Bridget A. Knight,Penelope A. Lind,Mark I. McCarthy,Mark I. McCarthy,Mark I. McCarthy,George McMahon,Sarah E. Medland,Mads Melbye,Mads Melbye,Andrew P. Morris,Andrew P. Morris,Michael Nodzenski,Christoph Reichetzeder,Christoph Reichetzeder,Susan M. Ring,Sylvain Sebert,Sylvain Sebert,Verena Sengpiel,Thorkild I. A. Sørensen,Thorkild I. A. Sørensen,Gonneke Willemsen,Gonneke Willemsen,Eco J. C. de Geus,Eco J. C. de Geus,Nicholas G. Martin,Tim D. Spector,Christine Power,Marjo-Riitta Järvelin,Hans Bisgaard,Struan F.A. Grant,Struan F.A. Grant,Ellen A. Nohr,Vincent W. V. Jaddoe,Bo Jacobsson,Bo Jacobsson,Jeff Murray,Berthold Hocher,Berthold Hocher,Andrew T. Hattersley,Denise M. Scholtens,George Davey Smith,Marie-France Hivert,Marie-France Hivert,Janine F. Felix,Elina Hyppönen,Elina Hyppönen,William L. Lowe,Timothy M. Frayling,Debbie A Lawlor,Rachel M. Freathy,Rachel M. Freathy +89 more
TL;DR: Citing this paper Please note that where the full-text provided on King's Research Portal is the Author Accepted Manuscript or Post-Print version this may differ from the final Published version.
Journal ArticleDOI
Heavier smoking may lead to a relative increase in waist circumference: evidence for a causal relationship from a Mendelian randomisation meta-analysis. The CARTA consortium.
Richard W Morris,Amy E Taylor,Meg E Fluharty,Johan Håkon Bjørngaard,Bjørn Olav Åsvold,Maiken Elvestad Gabrielsen,Archie Campbell,Riccardo E. Marioni,Riccardo E. Marioni,Meena Kumari,Tellervo Korhonen,Tellervo Korhonen,Tellervo Korhonen,Satu Männistö,Pedro Marques-Vidal,Marika Kaakinen,Alana Cavadino,Alana Cavadino,Iris Postmus,Lise Lotte N. Husemoen,Tea Skaaby,Tarunveer S. Ahluwalia,Tarunveer S. Ahluwalia,Jorien L. Treur,Gonneke Willemsen,Caroline Dale,S. Goya Wannamethee,Jari Lahti,Aarno Palotie,Aarno Palotie,Aarno Palotie,Katri Räikkönen,Alex McConnachie,Sandosh Padmanabhan,Andrew Wong,Christine Dalgård,Lavinia Paternoster,Yoav Ben-Shlomo,Jessica Tyrrell,John Horwood,David M. Fergusson,Martin A. Kennedy,Ellen A. Nohr,Lene Christiansen,Kirsten Ohm Kyvik,Diana Kuh,Graham Watt,Johan G. Eriksson,Peter H. Whincup,Jacqueline M. Vink,Dorret I. Boomsma,George Davey Smith,Debbie A Lawlor,Allan Linneberg,Ian Ford,J. Wouter Jukema,Chris Power,Elina Hyppönen,Elina Hyppönen,Marjo-Riitta Järvelin,Martin Preisig,Katja Borodulin,Jaakko Kaprio,Jaakko Kaprio,Mika Kivimäki,Blair H. Smith,Caroline Hayward,Pål Richard Romundstad,Thorkild I. A. Sørensen,Marcus R. Munafò,Naveed Sattar +70 more
TL;DR: For a given BMI, a gene variant associated with increased cigarette consumption was associated with increase waist circumference, suggesting that smoking in an effort to control weight may lead to accumulation of central adiposity.
GWAS on longitudinal growth traits reveals different genetic factors influencing infant, child, and adult BMI
Alexessander Couto Alves,N. Maneka G. De Silva,Ville Karhunen,Ulla Sovio,Shikta Das,H. Rob Taal,Nicole M. Warrington,Alexandra Lewin,Marika Kaakinen,Diana L. Cousminer,Elisabeth Thiering,Nicholas J. Timpson,Tom Bond,Estelle Lowry,Christopher D. Brown,Xavier Estivill,Virpi Lindi,Jonathan P. Bradfield,Frank Geller,Doug Speed,Lachlan J. M. Coin,Marie Loh,Sheila J. Barton,Lawrence J. Beilin,Hans Bisgaard,Klaus Bønnelykke,Rohia Alili,Ida J. Hatoum,Katharina Schramm,Rufus Cartwright,Marie-Aline Charles,Vincenzo Salerno,Karine Clément,Annique Claringbould,Cornelia M. van Duijn,Elena Moltchanova,Johan G. Eriksson,Cathy E. Elks,Bjarke Feenstra,Claudia Flexeder,Stephen Franks,Timothy M. Frayling,Rachel M. Freathy,Paul Elliott,Elisabeth Widen,Hakon Hakonarson,Andrew T. Hattersley,Alina Rodriguez,Marco Banterle,Joachim Heinrich,Barbara Heude,John W. Holloway,Albert Hofman,Elina Hyppönen,Hazel Inskip,Lee M. Kaplan,Åsa K. Hedman,Esa Läärä,Holger Prokisch,Harald Grallert,Timo A. Lakka,Debbie A Lawlor,Mads Melbye,Tarunveer S. Ahluwalia,Marcella Marinelli,Iona Y Millwood,Lyle J. Palmer,Craig E. Pennell,John R. B. Perry,Susan M. Ring,Markku J. Savolainen,Fernando Rivadeneira,Marie Standl,J Sunyer,Carla M. T. Tiesler,André G. Uitterlinden,William Schierding,Justin M. O'Sullivan,Inga Prokopenko,Karl-Heinz Herzig,George Davey Smith,Paul F. O'Reilly,Janine F. Felix,Jessica L. Buxton,Alexandra I. F. Blakemore,Ken K. Ong,Vincent W. V. Jaddoe,Struan F.A. Grant,Sylvain Sebert,Mark I. McCarthy,Marjo-Riitta Järvelin +90 more
TL;DR: In this paper, the authors combine genome-wide association studies with modeling of longitudinal growth traits to study the genetics of infant and child growth, followed by functional, pathway, genetic correlation, risk score, and colocalization analyses to determine how developmental timings, molecular pathways, and genetic determinants of these traits overlap with those of adult health.
Journal ArticleDOI
Hyperglycemia, Type 2 Diabetes, and Depressive Symptoms: The British Whitehall II study
Mika Kivimäki,Adam G. Tabak,G. David Batty,Archana Singh-Manoux,Markus Jokela,Tasnime N. Akbaraly,Daniel R. Witte,Eric J. Brunner,Michael Marmot,Debbie A Lawlor +9 more
TL;DR: The U-shaped association between blood glucose and CES-D, with the lowest depression risk seen among those in the normoglycemic range of A1C, did not support the hypothesized protective effect of hyperglycemia.