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Denise Krch

Researcher at City University of New York

Publications -  7
Citations -  825

Denise Krch is an academic researcher from City University of New York. The author has contributed to research in topics: Medicine & Computer science. The author has an hindex of 2, co-authored 2 publications receiving 769 citations.

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Venezuelan kindreds reveal that genetic and environmental factors modulate Huntington's disease age of onset

Nancy S. Wexler, +57 more
TL;DR: A model estimated the components of additive genetic, shared environment, and nonshared environment variances confirming that approximately 40% of the variance remaining in onset age is attributable to genes other than the HD gene and 60% is environmental.
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The relationship between CAG repeat length and age of onset differs for Huntington's disease patients with juvenile onset or adult onset.

J. Michael Andresen, +96 more
TL;DR: In this article, a two-segment exponential regression model was proposed for age-of-obstinence analysis of the CAG repeat expansion in the HD gene, and a plot of natural log-transformed age of onset against CAG-repeat length revealed this segmental relationship.
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Validation of the Norma Latina neuropsychological assessment battery in individuals with multiple sclerosis in Mexico.

TL;DR: In this article , the authors evaluated the neuropsychological profile of Mexican people with MS and assessed the utility of Norma Latina, a new battery for cognitive assessment in Latin America, in differentiating cognitive test performance between PwMS and healthy controls (HCs).
Posted ContentDOI

Bridging Big Data: Procedures for Combining Non-equivalent Cognitive Measures from the ENIGMA Consortium

Eamonn Kennedy, +143 more
- 19 Jan 2023 - 
TL;DR: In this article , the authors focus on the most frequently assessed cognitive domain -memory testing - and demonstrate a process for reliable data harmonization across three common measures, and demonstrate that large-scale data sharing and harmonization initiatives can address reproducibility and integration challenges across the behavioral sciences.
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Rationale and methodology for examining the acute effects of aerobic exercise combined with varying degrees of virtual reality immersion on cognition in persons with TBI

TL;DR: In this paper , an acute exercise study was conducted to investigate the acute effects of aerobic exercise with incremental degrees of environmental enrichment relative to a control comparison condition on executive function (divided attention and working memory) and processing speed in 24 people with Traumatic Brain Injury.