D
Diederick E. Grobbee
Researcher at Utrecht University
Publications - 1108
Citations - 136069
Diederick E. Grobbee is an academic researcher from Utrecht University. The author has contributed to research in topics: Population & Risk factor. The author has an hindex of 155, co-authored 1051 publications receiving 122748 citations. Previous affiliations of Diederick E. Grobbee include National Heart Foundation of Australia & Radboud University Nijmegen Medical Centre.
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Journal Article
Primary prevention in hypertension. Valid conclusions from observational studies.
TL;DR: It is concluded that observational studies could play an increasing role in the assessment of the role of antihypertensive therapy in the primary prevention of coronary heart disease when the inherent potentials and pitfalls of these studies are appreciated.
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No added value of age at menopause and the lifetime cumulative number of menstrual cycles for cardiovascular risk prediction in postmenopausal women
Femke Atsma,Yvonne T. van der Schouw,Diederick E. Grobbee,Arno W. Hoes,Marie-Louise Bartelink +4 more
TL;DR: The findings in this study among postmenopausal women did not support the view that age at menopause or a refined estimation of lifetime endogenous estrogen exposure would improve cardiovascular risk prediction as approximated by the ankle-arm index.
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Pragmatic trial design elements showed a different impact on trial interpretation and feasibility than explanatory elements.
Joost B. Nieuwenhuis,Elaine A. Irving,Katrien Oude Rengerink,Emily Lloyd,Iris Goetz,Diederick E. Grobbee,Pieter Stolk,Rolf H.H. Groenwold,Mira G. P. Zuidgeest +8 more
TL;DR: Consequences of incorporating pragmatic or explanatory trial design elements in pragmatic trials should be explicitly considered and balanced for all relevant domains, including validity, generalizability, precision, and operational feasibility.
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Working together in cardiovascular prevention: the common mission of the European Heart Journal and the European Journal of Preventive Cardiology.
TL;DR: With an increasing number of trials documenting the benefits of blood pressure lowering, the use of diuretics, beta-blockers, calcium antagonists, and inhibitors of the renin–angiotension–aldosterone system became increasingly widespread and the decline in the incidence of stroke in many Western countries is a major success of preventive cardiovascular medicine.
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The Utrecht questionnaire (U-CEP) measuring knowledge on clinical epidemiology proved to be valid
Marlous F Kortekaas,Marie Louise E.L. Bartelink,Esther de Groot,Helen Korving,Niek J. de Wit,Diederick E. Grobbee,Arno W. Hoes +6 more
TL;DR: The Utrecht questionnaire on knowledge on Clinical epidemiology for Evidence-based Practice (U-CEP) is a valid questionnaire to assess knowledge on clinical epidemiology, which is a prerequisite for practicing evidence-based medicine in daily clinical practice.