D
Diederick E. Grobbee
Researcher at Utrecht University
Publications - 1108
Citations - 136069
Diederick E. Grobbee is an academic researcher from Utrecht University. The author has contributed to research in topics: Population & Risk factor. The author has an hindex of 155, co-authored 1051 publications receiving 122748 citations. Previous affiliations of Diederick E. Grobbee include National Heart Foundation of Australia & Radboud University Nijmegen Medical Centre.
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In-hospital morbidity and mortality due to severe malarial anemia in western Kenya.
TL;DR: In areas of high malaria transmission, children below 3 years are a high-risk group for malaria, anemia, blood transfusion, and mortality, and children under 5 years of age admitted to Siaya district hospital, western Kenya were the most at risk.
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Seasonal variation in cause-specific mortality: are there high-risk groups? 25-year follow-up of civil servants from the first Whitehall study.
Caroline T M van Rossum,Martin J. Shipley,Harry Hemingway,Diederick E. Grobbee,Johan P. Mackenbach,Michael Marmot +5 more
TL;DR: Seasonal mortality differences were greater among those with prevalent ischaemic heart disease and at older ages, but were not greater in individuals of lower socioeconomic status or with a high multivariate risk score.
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Prognosis of stroke in the south of Greece: 1 year mortality, functional outcome and its determinants: the Arcadia Stroke Registry
K. Vemmos,Michiel L. Bots,P K Tsibouris,V P Zis,C E Takis,Diederick E. Grobbee,S Stamatelopoulos +6 more
TL;DR: One year mortality from stroke in Greece is similar to that of other industrialised countries, and the most important factors that affect the prognosis of a patient with a first ever stroke are increasing age, stroke severity, and atrial fibrillation.
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A simple method to adjust clinical prediction models to local circumstances.
TL;DR: It is shown how a simple updating method may suffice to update a clinical prediction model when a previously developed model is validated and the performance is poor, and may yield better risk estimates.
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CETP genotype predicts increased mortality in statin-treated men with proven cardiovascular disease: an adverse pharmacogenetic interaction.
Jakub J. Regieli,J. Wouter Jukema,Diederick E. Grobbee,John J. P. Kastelein,Jan Albert Kuivenhoven,Aeilko H. Zwinderman,Yolanda van der Graaf,Michiel L. Bots,Pieter A. Doevendans +8 more
TL;DR: In statin-treated male CAD patients, genetic variation conferring low CETP levels is associated with increased 10-year mortality, suggesting that efficacy of statin therapy to reduce cardiovascular risk depends on CETP genotype and associated CETP plasma levels.