D
Diederick E. Grobbee
Researcher at Utrecht University
Publications - 1108
Citations - 136069
Diederick E. Grobbee is an academic researcher from Utrecht University. The author has contributed to research in topics: Population & Risk factor. The author has an hindex of 155, co-authored 1051 publications receiving 122748 citations. Previous affiliations of Diederick E. Grobbee include National Heart Foundation of Australia & Radboud University Nijmegen Medical Centre.
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Journal ArticleDOI
Subsequent Event Risk in Individuals with Established Coronary Heart Disease: Design and Rationale of the GENIUS-CHD Consortium.
Riyaz S. Patel,Riyaz S. Patel,Vinicius Tragante,Amand F. Schmidt,Raymond O McCubrey,Michael V. Holmes,Michael V. Holmes,Laurence J. Howe,Kenan Direk,Axel Åkerblom,Karin Leander,Salim S. Virani,Salim S. Virani,Karol Kamiński,Jochen D. Muehlschlegel,Jochen D. Muehlschlegel,Hooman Allayee,Peter Almgren,Maris Alver,Ekaterina V Baranova,Hassan Behloui,Bram Boeckx,Peter S. Braund,Peter S. Braund,Lutz P. Breitling,Graciela E. Delgado,Nubia E. Duarte,Marie-Pierre Dubé,Marie-Pierre Dubé,Line Dufresne,Niclas Eriksson,Luisa Foco,Markus Scholz,Crystel M. Gijsberts,Charlotte Glinge,Charlotte Glinge,Yan Gong,Jaana Hartiala,Mahyar Heydarpour,Mahyar Heydarpour,Jaroslav A. Hubacek,Marcus E. Kleber,Daniel Kofink,Salma Kotti,Pekka Kuukasjärvi,Vei-Vei Lee,Andreas Leiherer,Petra A. Lenzini,Daniel Levin,Leo-Pekka Lyytikäinen,Nicola Martinelli,Ute Mons,Christopher P. Nelson,Christopher P. Nelson,Kjell Nikus,Anna P. Pilbrow,Rafał Płoski,Yan V. Sun,Michael W.T. Tanck,W.H. Wilson Tang,W.H. Wilson Tang,Stella Trompet,Sander W. van der Laan,Jessica van Setten,Ragnar O. Vilmundarson,Chiara Viviani Anselmi,Efthymia Vlachopoulou,Lawien Al Ali,Eric Boerwinkle,Carlo Briguori,John F. Carlquist,John F. Carlquist,Kathryn F. Carruthers,Gavino Casu,John E. Deanfield,John E. Deanfield,Panos Deloukas,Frank Dudbridge,Thomas Engstrøm,Thomas Engstrøm,Natalie K Fitzpatrick,Kim Fox,Bruna Gigante,Stefan James,Marja-Liisa Lokki,Paulo A. Lotufo,Nicola Marziliano,Ify R. Mordi,Joseph B. Muhlestein,Joseph B. Muhlestein,Christopher Newton-Cheh,Christopher Newton-Cheh,Jan Pitha,Christoph H. Saely,Ayman Samman-Tahhan,Pratik B. Sandesara,Andrej Teren,Adam Timmis,Adam Timmis,Frans Van de Werf,Els Wauters,Arthur A.M. Wilde,Ian Ford,David J. Stott,Ale Algra,Maria G. Andreassi,Diego Ardissino,Benoit J. Arsenault,Christie M. Ballantyne,Thomas O. Bergmeijer,Connie R. Bezzina,Simon C. Body,Simon C. Body,Eric Boersma,Peter Bogaty,Michiel L. Bots,Hermann Brenner,Jasper J. Brugts,Ralph Burkhardt,Ralph Burkhardt,Clara Carpeggiani,Gianluigi Condorelli,Rhonda M. Cooper-DeHoff,Sharon Cresci,Nicolas Danchin,Ulf de Faire,Robert N. Doughty,Heinz Drexel,James C. Engert,Keith A.A. Fox,Domenico Girelli,Diederick E. Grobbee,Emil Hagström,Stanley L. Hazen,Stanley L. Hazen,Claes Held,Harry Hemingway,Imo E. Hoefer,G. Kees Hovingh,Reza Jabbari,Julie A. Johnson,J. Wouter Jukema,J. Wouter Jukema,Marcin P. Kaczor,Mika Kähönen,Jiri Kettner,Marek Kiliszek,Olaf H. Klungel,Bo Lagerqvist,Diether Lambrechts,Jari Laurikka,Terho Lehtimäki,Dan Lindholm,Bakhtawar K. Mahmoodi,Anke H. Maitland-van der Zee,Anke H. Maitland-van der Zee,Ruth McPherson,Olle Melander,Andres Metspalu,Anna Niemcunowicz-Janica,Oliviero Olivieri,Grzegorz Opolski,Colin N. A. Palmer,Gerard Pasterkamp,Carl J. Pepine,Alexandre C. Pereira,Louise Pilote,Arshed A. Quyyumi,A. Mark Richards,A. Mark Richards,Marek Sanak,Agneta Siegbahn,Tabassome Simon,Tabassome Simon,Juha Sinisalo,J. Gustav Smith,J. Gustav Smith,John A. Spertus,Steen Stender,Alexandre F.R. Stewart,Wojciech Szczeklik,Anna Szpakowicz,Jean-Claude Tardif,Jean-Claude Tardif,Jurriën M. ten Berg,Jacob Tfelt-Hansen,Jacob Tfelt-Hansen,George Thanassoulis,Joachim Thiery,Christian Torp-Pedersen,Yolanda van der Graaf,Frank L.J. Visseren,Johannes Waltenberger,Peter Weeke,Pim van der Harst,Chim C. Lang,Naveed Sattar,Vicky A. Cameron,Jeffrey L. Anderson,Jeffrey L. Anderson,James M. Brophy,Guillaume Paré,Guillaume Paré,Benjamin D. Horne,Benjamin D. Horne,Winfried März,Winfried März,Winfried März,Lars Wallentin,Nilesh J. Samani,Nilesh J. Samani,Aroon D. Hingorani,Folkert W. Asselbergs +212 more
TL;DR: The Genetics of Subsequent Coronary Heart Disease (GENIUS-CHD) consortium was established to facilitate discovery and validation of genetic variants and biomarkers for risk of subsequent CHD events, in individuals with established CHD as discussed by the authors.
Journal ArticleDOI
Vascular status and physical functioning: the association between vascular status and physical functioning in middle-aged and elderly men: a cross-sectional study
Ilse E.M.A. Arts,Ilse E.M.A. Arts,Marieke Schuurmans,Diederick E. Grobbee,Yvonne T. van der Schouw +4 more
TL;DR: This study showed no age-independent association between the extent of vascular damage and physical performance and muscle strength in middle aged and elderly men.
Journal ArticleDOI
Do polypills lead to neglect of lifestyle risk factors? Findings from an individual participant data meta-analysis among 3140 patients at high risk of cardiovascular disease.
Vanessa Selak,Chris Bullen,Sandrine Stepien,Bruce Arroll,Michiel L. Bots,Dale Bramley,Alan Cass,Diederick E. Grobbee,Graham S. Hillis,Barbara Molanus,Bruce Neal,Anushka Patel,Natasha Rafter,Natasha Rafter,Anthony Rodgers,Simon Thom,Andrew Tonkin,Tim Usherwood,Angela Wadham,Ruth Webster +19 more
TL;DR: There was no difference in lifestyle risk factors in those randomised to polypill-based care compared with usual care over a median of 15 months, either across all participants combined, or in a range of subgroups.
Journal ArticleDOI
The Moderate Alcohol and Cardiovascular Health Trial (MACH15): Design and methods for a randomized trial of moderate alcohol consumption and cardiometabolic risk:
Donna Spiegelman,Laura C. Lovato,Laura C. Lovato,Polyna Khudyakov,Polyna Khudyakov,T.L. Wilkens,Clement Adebamowo,Sally N. Adebamowo,Lawrence J. Appel,Joline W. J. Beulens,Joline W. J. Beulens,Janelle W. Coughlin,Lars O. Dragsted,Howard J. Edenberg,Jane N. Eriksen,Ramon Estruch,Ramon Estruch,Diederick E. Grobbee,Pablo Gulayin,Vilma Irazola,John H. Krystal,Mariana Lazo,Margaret M. Murray,Eric B. Rimm,Eric B. Rimm,Ilse C. Schrieks,Jeff D. Williamson,Kenneth J. Mukamal +27 more
TL;DR: A feasible design for a long-term randomized trial of moderate alcohol consumption will provide the highest level of evidence for the effects ofmoderate alcohol consumption on cardiovascular disease and diabetes, and will directly inform clinical and public health guidelines.
Journal ArticleDOI
Sudden Cardiac Death in Patients with Hypertension
TL;DR: Although it was suggested in the 2 recent case-control studies that recipients of β-blockers are also at an increased risk of sudden death, further studies are required to confirm this finding, particularly since these drugs have several well-documented cardioprotective effects.