D
Diederick E. Grobbee
Researcher at Utrecht University
Publications - 1108
Citations - 136069
Diederick E. Grobbee is an academic researcher from Utrecht University. The author has contributed to research in topics: Population & Risk factor. The author has an hindex of 155, co-authored 1051 publications receiving 122748 citations. Previous affiliations of Diederick E. Grobbee include National Heart Foundation of Australia & Radboud University Nijmegen Medical Centre.
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Journal ArticleDOI
Manual B-mode versus automated radio-frequency carotid intima-media thickness measurements.
Soner Dogan,Yvonne Plantinga,Joke M. Dijk,Yolanda van der Graaf,Diederick E. Grobbee,Michiel L. Bots +5 more
TL;DR: The B-mode approach was shown to be robust in risk-factor relations and the prediction of events, as in many others.
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Impact of switching from different treatment regimens to a fixed-dose combination pill (polypill) in patients with cardiovascular disease or similarly high risk.
Melvin Lafeber,Wilko Spiering,Frank L.J. Visseren,Diederick E. Grobbee,Michiel L. Bots,Alice Stanton,Anushka Patel,Dorairaj Prabhakaran,Ruth Webster,Simon Thom,Anthony Rodgers +10 more
TL;DR: Switching to a polypill-based strategy resulted in estimated cardiovascular relative risk reductions across a wide range of usual care patterns of antiplatelet, statin and BP-lowering therapy prescribing, including equally potent or more potent regimens.
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High IGFBP2 levels are not only associated with a better metabolic risk profile but also with increased mortality in elderly men.
Annewieke W. van den Beld,Werner F. Blum,Michael P. Brugts,Joop A. M. J. L. Janssen,Diederick E. Grobbee,Steven W. J. Lamberts +5 more
TL;DR: IGFBP2 may be a useful biomarker integrating the nutritional status, as well as the biological effects of GH, IGF1, and insulin, and higher IGFBP2 levels were significantly associated with lower albumin concentrations.
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Aspects of the aetiology of congenital heart disease
TL;DR: Large-scale epidemiological studies on fetuses and neonates with congenital heart disease are introduced as a third mode of research on the aetiology, although this approach is not used efficiently at present.
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Predicting functional decline in older patients undergoing cardiac surgery
TL;DR: The amended ISAR-HP used in older cardiac surgery patients showed good discriminative values at score ≥1, supporting the generalisability of this prediction model for this patient group.