D
Diederick E. Grobbee
Researcher at Utrecht University
Publications - 1108
Citations - 136069
Diederick E. Grobbee is an academic researcher from Utrecht University. The author has contributed to research in topics: Population & Risk factor. The author has an hindex of 155, co-authored 1051 publications receiving 122748 citations. Previous affiliations of Diederick E. Grobbee include National Heart Foundation of Australia & Radboud University Nijmegen Medical Centre.
Papers
More filters
Journal ArticleDOI
Age at menopause, cause-specific mortality and total life expectancy.
Marlies E Ossewaarde,Michiel L. Bots,André L. M. Verbeek,Petra H.M. Peeters,Yolanda van der Graaf,Diederick E. Grobbee,Yvonne T. van der Schouw +6 more
TL;DR: Age-adjusted mortality is reduced 2% with each increasing year of age at menopause, and ischemic heart disease mortality is 2% lower, although the risk of death from uterine or ovarian cancer is increased by 5%, the net effect of a later menoppause is an increased lifespan.
Journal ArticleDOI
Cognitive correlates of ventricular enlargement and cerebral white matter lesions on magnetic resonance imaging. The Rotterdam Study.
Monique M.B. Breteler,N. M. Van Amerongen,J. C. van Swieten,J. J. Claus,Diederick E. Grobbee,J. Van Gijn,Albert Hofman,F. van Harskamp +7 more
TL;DR: This study suggests that white matter lesions are primarily related to impairment of subcorticofrontal functions, whereas enlargement of the lateral ventricles is associated with disturbances of cortical functions as well.
Journal ArticleDOI
Increased Common Carotid Intima-Media Thickness: Adaptive Response or a Reflection of Atherosclerosis? Findings From the Rotterdam Study
TL;DR: The findings are compatible with the view that at lower degrees of IMT, the thickening appears to reflect an equilibrium state in which the effects of pressure and flow on the arteries are in balance, given a characteristic relation between shear stress and local transmural pressure.
Journal ArticleDOI
Estimating interaction on an additive scale between continuous determinants in a logistic regression model
Mirjam J. Knol,Ingeborg van der Tweel,Diederick E. Grobbee,Mattijs E. Numans,Mirjam I. Geerlings +4 more
TL;DR: The methods and formulas presented in this article are intended to assist epidemiologists to calculate interaction on an additive scale between two variables on a certain outcome.
Journal ArticleDOI
Endogenous sex hormones in men aged 40-80 years
Majon Muller,Isolde den Tonkelaar,Jos H.H. Thijssen,Diederick E. Grobbee,Yvonne T. van der Schouw +4 more
TL;DR: It can be concluded that general health status modified the effect between sex hormones and age, and the important determinants of sex hormones were age, BMI, waist circumference, smoking, general healthstatus and physical activity.