D
Diederick E. Grobbee
Researcher at Utrecht University
Publications - 1108
Citations - 136069
Diederick E. Grobbee is an academic researcher from Utrecht University. The author has contributed to research in topics: Population & Risk factor. The author has an hindex of 155, co-authored 1051 publications receiving 122748 citations. Previous affiliations of Diederick E. Grobbee include National Heart Foundation of Australia & Radboud University Nijmegen Medical Centre.
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Journal ArticleDOI
Thyroid hormone concentrations, disease, physical function, and mortality in elderly men.
Annewieke W. van den Beld,Theo J. Visser,Richard A Feelders,Diederick E. Grobbee,Steven W. J. Lamberts +4 more
TL;DR: In a population of independently living elderly men, higher FT4 and rT3 concentrations are associated with a lower physical function, which may result from a decreased peripheral metabolism of thyroid hormones due to the aging process itself and/or disease and may reflect a catabolic state.
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Homocysteine and short-term risk of myocardial infarction and stroke in the elderly: the Rotterdam Study.
Michiel L. Bots,Lenore J. Launer,Jan Lindemans,Arno W. Hoes,Albert Hofman,Jacqueline C.M. Witteman,Peter J. Koudstaal,Diederick E. Grobbee +7 more
TL;DR: In this article, the authors examined the relationship of homocysteine level to incident myocardial infarction and stroke among older subjects in a nested case-control study.
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Association of radiographically evident osteoarthritis with higher bone mineral density and increased bone loss with age. The Rotterdam Study.
H. Burger,Paulus L. A. van Daele,Else Odding,Hans A. Valkenburg,Albert Hofman,Diederick E. Grobbee,Henry E. Schütte,Jan C. Birkenhäger,Huibert A. P. Pols +8 more
TL;DR: Radiographic OA is associated with high BMD and increased rate of bone loss with age, which suggests a more pronounced difference in BMD earlier in life.
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Lowering Blood Pressure Reduces Renal Events in Type 2 Diabetes
Bastiaan E. de Galan,Bastiaan E. de Galan,Vlado Perkovic,Toshiharu Ninomiya,Avinesh Pillai,Anushka Patel,Alan Cass,Bruce Neal,Neil R Poulter,Stephen B. Harrap,Carl Erik Mogensen,Mark E. Cooper,Michel Marre,Bryan Williams,Pavel Hamet,Giuseppe Mancia,Mark Woodward,Paul Glasziou,Diederick E. Grobbee,Stephen MacMahon,John Chalmers +20 more
TL;DR: BP-lowering treatment with perindopril-indapamide administered routinely to individuals with type 2 diabetes provides important renoprotection, even among those with initial BP <120/70 mmHg, and a BP threshold below which renal benefit is lost is not identified.
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Determinants of peripheral arterial disease in the elderly: The Rotterdam Study
TL;DR: In this article, the authors examined which atherosclerotic risk factors are determinants for peripheral arterial disease (PAD), and concluded that preventive management of PAD should be directed at systolic blood pressure, fibrinogen level, smoking, high-density lipoprotein cholesterol level, and diabetes mellitus.