F
Francesco M. Marincola
Researcher at National Institutes of Health
Publications - 473
Citations - 41473
Francesco M. Marincola is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Immune system & Antigen. The author has an hindex of 94, co-authored 462 publications receiving 38129 citations. Previous affiliations of Francesco M. Marincola include Society for Immunotherapy of Cancer & Virginia Commonwealth University.
Papers
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Journal ArticleDOI
Molecular classification of cutaneous malignant melanoma by gene expression profiling
M. Bittner,Paul S. Meltzer,Yi Chen,Yong-hui Jiang,E. A. Seftor,Mary J.C. Hendrix,Michael D. Radmacher,Richard M. Simon,Zohar Yakhini,Amir Ben-Dor,Amir Ben-Dor,Nick Sampas,Edward R. Dougherty,Ena Wang,Francesco M. Marincola,C. Gooden,John Lueders,Arthur A. Glatfelter,P.C.A. Pollock,John D. Carpten,E. Gillanders,D. Leja,K. Dietrich,Christian Beaudry,Michael E. Berens,David S. Alberts,Vernon K. Sondak,Nicholas K. Hayward,J.M. Trent +28 more
TL;DR: Many genes underlying the classification of this subset of melanomas are differentially regulated in invasive melanomas that form primitive tubular networks in vitro, a feature of some highly aggressive metastatic melanomas.
Journal ArticleDOI
Immunologic and therapeutic evaluation of a synthetic peptide vaccine for the treatment of patients with metastatic melanoma
Steven A. Rosenberg,James Chih-Hsin Yang,Douglas J. Schwartzentruber,Patrick Hwu,Francesco M. Marincola,Suzanne L. Topalian,Nicholas P. Restifo,Mark E. Dudley,Susan L. Schwarz,Paul J. Spiess,John R. Wunderlich,Maria R. Parkhurst,Yutaka Kawakami,Claudia A. Seipp,Jan Einhorn,Donald E. White +15 more
TL;DR: A synthetic peptide, designed to increase binding to HLA-A2 molecules, was used as a cancer vaccine to treat patients with metastatic melanoma and, on the basis of immunologic assays, 91% of patients could be successfully immunized with this peptide.
Journal ArticleDOI
A human memory T cell subset with stem cell-like properties
Luca Gattinoni,Enrico Lugli,Yun Ji,Zoltan Pos,Chrystal M. Paulos,Máire F. Quigley,Máire F. Quigley,Jorge R. Almeida,Emma Gostick,Zhiya Yu,Carmine Carpenito,Ena Wang,Daniel C. Douek,David Price,David Price,Carl H. June,Francesco M. Marincola,Mario Roederer,Nicholas P. Restifo +18 more
TL;DR: A long-lived human memory T cell population that has an enhanced capacity for self-renewal and a multipotent ability to derive central memory, effector memory and effector T cells is described.
Book ChapterDOI
Escape of human solid tumors from T-cell recognition: molecular mechanisms and functional significance.
TL;DR: This important finding suggests that TAA-specific CTL may be present in some cancer patients but are unable to attack tumor cells due to the presence of inhibitory receptors.
Journal ArticleDOI
Towards the introduction of the 'Immunoscore' in the classification of malignant tumours.
Jérôme Galon,Jérôme Galon,Jérôme Galon,Bernhard Mlecnik,Bernhard Mlecnik,Bernhard Mlecnik,Gabriela Bindea,Gabriela Bindea,Gabriela Bindea,Helen K. Angell,Helen K. Angell,Helen K. Angell,Anne Berger,Christine Lagorce,Alessandro Lugli,Inti Zlobec,Arndt Hartmann,Carlo Bifulco,Iris D. Nagtegaal,Richard Palmqvist,Giuseppe Masucci,Gerardo Botti,Fabiana Tatangelo,Paolo Delrio,Michele Maio,Luigi Laghi,Fabio Grizzi,Martin Asslaber,Corrado D'Arrigo,Fernando Vidal-Vanaclocha,Eva Zavadova,Lotfi Chouchane,Pamela S. Ohashi,Sara Hafezi-Bakhtiari,Bradly G. Wouters,Michael H.A. Roehrl,Linh V. Nguyen,Yutaka Kawakami,Shoichi Hazama,Kiyotaka Okuno,Shuji Ogino,Peter Gibbs,Paul Waring,Noriyuki Sato,Toshihiko Torigoe,Kyogo Itoh,P. Patel,Shilin N. Shukla,Yili Wang,Scott Kopetz,Frank A. Sinicrope,Viorel Scripcariu,Paolo A. Ascierto,Francesco M. Marincola,Bernard A. Fox,Bernard A. Fox,Franck Pagès +56 more
TL;DR: In colorectal cancer, the Immunoscore may add to the significance of the current AJCC/UICC TNM classification, since it has been demonstrated to be a prognostic factor superior to the AJCC or UICCTNM classification.