G
George Grills
Researcher at University of Miami
Publications - 33
Citations - 2667
George Grills is an academic researcher from University of Miami. The author has contributed to research in topics: Medicine & DNA sequencing. The author has an hindex of 9, co-authored 22 publications receiving 2152 citations. Previous affiliations of George Grills include Harvard University & Cornell University.
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Journal ArticleDOI
A first-generation haplotype map of maize
Michael A. Gore,Jer Ming Chia,Robert J. Elshire,Qi Sun,Elhan S. Ersoz,Bonnie L. Hurwitz,Jason A. Peiffer,Michael D. McMullen,Michael D. McMullen,George Grills,Jeffrey Ross-Ibarra,Doreen Ware,Doreen Ware,Edward S. Buckler,Edward S. Buckler +14 more
TL;DR: A survey of genetic diversity in maize found hundreds of selective sweeps and highly differentiated regions that probably contain loci that are key to geographic adaptation and provide a foundation for uniting breeding efforts across the world and for dissecting complex traits through genome-wide association studies.
Journal ArticleDOI
Genomic analysis reveals that Pseudomonas aeruginosa virulence is combinatorial
Daniel G. Lee,Jonathan M. Urbach,Gang Wu,Nicole T. Liberati,Rhonda L. Feinbaum,Sachiko Miyata,Lenard T Diggins,Jianxin He,Maude Saucier,Maude Saucier,Eric Déziel,Eric Déziel,Lisa Friedman,Lisa Friedman,Li Li,George Grills,George Grills,Kate Montgomery,Raju Kucherlapati,Laurence G. Rahme,Frederick M. Ausubel +20 more
TL;DR: It is proposed that virulence in this organism is both multifactorial and combinatorial, the result of a pool of pathogenicity-related genes that interact in various combinations in different genetic backgrounds.
Journal ArticleDOI
The NASA Twins Study: A multidimensional analysis of a year-long human spaceflight.
Francine E. Garrett-Bakelman,Francine E. Garrett-Bakelman,Manjula Darshi,Stefan J. Green,Ruben C. Gur,Ling Lin,Brandon R. Macias,Miles J. McKenna,Cem Meydan,Tejaswini Mishra,Jad Nasrini,Brian D. Piening,Brian D. Piening,Lindsay F. Rizzardi,Kumar Sharma,Jamila H. Siamwala,Jamila H. Siamwala,Lynn Taylor,Martha Hotz Vitaterna,Maryam Afkarian,Ebrahim Afshinnekoo,Sara Ahadi,Aditya Ambati,Maneesh Arya,Daniela Bezdan,Colin M. Callahan,Songjie Chen,Augustine M.K. Choi,George E. Chlipala,Kévin Contrepois,Marisa Covington,Brian Crucian,Immaculata De Vivo,David F. Dinges,Douglas J. Ebert,Jason I. Feinberg,Jorge Gandara,Kerry George,John Goutsias,George Grills,Alan R. Hargens,Martina Heer,Martina Heer,Ryan P. Hillary,Andrew N. Hoofnagle,Vivian Hook,Garrett Jenkinson,Garrett Jenkinson,Peng Jiang,Ali Keshavarzian,Steven S. Laurie,Brittany Lee-McMullen,Sarah B. Lumpkins,Matthew MacKay,Mark Maienschein-Cline,Ari Melnick,Tyler M. Moore,Kiichi Nakahira,Hemal H. Patel,Robert Pietrzyk,Varsha Rao,Rintaro Saito,Rintaro Saito,Denis Salins,Jan M. Schilling,Dorothy D. Sears,Caroline Sheridan,Michael B. Stenger,Rakel Tryggvadottir,Alexander E. Urban,Tomas Vaisar,Benjamin Van Espen,Jing Zhang,Michael G. Ziegler,Sara R. Zwart,John B. Charles,Craig E. Kundrot,Graham B. I. Scott,Susan M. Bailey,Mathias Basner,Andrew P. Feinberg,Stuart M. C. Lee,Christopher E. Mason,Emmanuel Mignot,Brinda K. Rana,Scott M. Smith,Michael Snyder,Fred W. Turek,Fred W. Turek +88 more
TL;DR: Given that the majority of the biological and human health variables remained stable, or returned to baseline, after a 340-day space mission, these data suggest that human health can be mostly sustained over this duration of spaceflight.
Journal ArticleDOI
Multi-platform assessment of transcriptome profiling using RNA-seq in the ABRF next-generation sequencing study
Sheng Li,Scott Tighe,Charles M Nicolet,Deborah S. Grove,Shawn Levy,William G. Farmerie,Agnes Viale,Chris L. Wright,Peter A. Schweitzer,Yuan Gao,Dewey Kim,Joe Boland,Belynda Hicks,Ryan W. Kim,Sagar Chhangawala,Nadereh Jafari,Nalini Raghavachari,Jorge Gandara,Natàlia Garcia-Reyero,Cynthia Hendrickson,David Roberson,Jeffrey A. Rosenfeld,Todd M. Smith,Jason G. Underwood,May D. Wang,Paul Zumbo,Don A. Baldwin,George Grills,Christopher E. Mason +28 more
TL;DR: This study provides a broad foundation for cross-platform standardization, evaluation and improvement of RNA-seq, showing high intraplatform and inter-platform concordance for expression measures across the deep-count platforms, but highly variable efficiency and cost for splice junction and variant detection between all platforms.
Journal ArticleDOI
Genomic characterization of non-O1, non-O139 Vibrio cholerae reveals genes for a type III secretion system
Michelle Dziejman,Davide Serruto,Vincent C. Tam,Derek Sturtevant,Pornphan Diraphat,Shah M. Faruque,M. Hasibur Rahman,John F. Heidelberg,Jeremy Decker,Li Li,Kate Montgomery,George Grills,Raju Kucherlapati,John J. Mekalanos +13 more
TL;DR: It is hypothesized that the TTSS present in some pathogenic strains of non-O1,non-O139 V. cholerae may be involved in the virulence and environmental fitness of these strains.