J
Jason I. Feinberg
Researcher at Johns Hopkins University
Publications - 32
Citations - 2075
Jason I. Feinberg is an academic researcher from Johns Hopkins University. The author has contributed to research in topics: DNA methylation & Epigenetics. The author has an hindex of 12, co-authored 23 publications receiving 1417 citations. Previous affiliations of Jason I. Feinberg include Johns Hopkins University School of Medicine & Center for Autism and Related Disorders.
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Journal ArticleDOI
The NASA Twins Study: A multidimensional analysis of a year-long human spaceflight.
Francine E. Garrett-Bakelman,Francine E. Garrett-Bakelman,Manjula Darshi,Stefan J. Green,Ruben C. Gur,Ling Lin,Brandon R. Macias,Miles J. McKenna,Cem Meydan,Tejaswini Mishra,Jad Nasrini,Brian D. Piening,Brian D. Piening,Lindsay F. Rizzardi,Kumar Sharma,Jamila H. Siamwala,Jamila H. Siamwala,Lynn Taylor,Martha Hotz Vitaterna,Maryam Afkarian,Ebrahim Afshinnekoo,Sara Ahadi,Aditya Ambati,Maneesh Arya,Daniela Bezdan,Colin M. Callahan,Songjie Chen,Augustine M.K. Choi,George E. Chlipala,Kévin Contrepois,Marisa Covington,Brian Crucian,Immaculata De Vivo,David F. Dinges,Douglas J. Ebert,Jason I. Feinberg,Jorge Gandara,Kerry George,John Goutsias,George Grills,Alan R. Hargens,Martina Heer,Martina Heer,Ryan P. Hillary,Andrew N. Hoofnagle,Vivian Hook,Garrett Jenkinson,Garrett Jenkinson,Peng Jiang,Ali Keshavarzian,Steven S. Laurie,Brittany Lee-McMullen,Sarah B. Lumpkins,Matthew MacKay,Mark Maienschein-Cline,Ari Melnick,Tyler M. Moore,Kiichi Nakahira,Hemal H. Patel,Robert Pietrzyk,Varsha Rao,Rintaro Saito,Rintaro Saito,Denis Salins,Jan M. Schilling,Dorothy D. Sears,Caroline Sheridan,Michael B. Stenger,Rakel Tryggvadottir,Alexander E. Urban,Tomas Vaisar,Benjamin Van Espen,Jing Zhang,Michael G. Ziegler,Sara R. Zwart,John B. Charles,Craig E. Kundrot,Graham B. I. Scott,Susan M. Bailey,Mathias Basner,Andrew P. Feinberg,Stuart M. C. Lee,Christopher E. Mason,Emmanuel Mignot,Brinda K. Rana,Scott M. Smith,Michael Snyder,Fred W. Turek,Fred W. Turek +88 more
TL;DR: Given that the majority of the biological and human health variables remained stable, or returned to baseline, after a 340-day space mission, these data suggest that human health can be mostly sustained over this duration of spaceflight.
Journal ArticleDOI
Total Synthesis of a Functional Designer Eukaryotic Chromosome
Narayana Annaluru,Héloïse Muller,Leslie A. Mitchell,Sivaprakash Ramalingam,Giovanni Stracquadanio,Sarah M. Richardson,Jessica S. Dymond,Zheng Kuang,Lisa Z. Scheifele,Eric M. Cooper,Yizhi Cai,Karen I. Zeller,Neta Agmon,Jeffrey S. Han,Michalis Hadjithomas,Jennifer Tullman,Katrina Caravelli,Kimberly M. Cirelli,Zheyuan Guo,Viktoriya London,Apurva Yeluru,Sindurathy Murugan,Karthikeyan Kandavelou,Nicolas Agier,Nicolas Agier,Gilles Fischer,Gilles Fischer,Kun Yang,J. Andrew Martin,Murat Bilgel,Pavlo Bohutski,Kristin M. Boulier,Brian J. Capaldo,Joy Chang,Kristie Charoen,Woo Jin Choi,Peter Deng,James E. DiCarlo,Judy Doong,Jessilyn Dunn,Jason I. Feinberg,Christopher Fernandez,Charlotte E. Floria,David Gladowski,Pasha Hadidi,Isabel E. Ishizuka,Javaneh Jabbari,Calvin Y. L. Lau,Pablo A. Lee,Sean Li,Denise Lin,Matthias E. Linder,Jonathan P. Ling,Jaime Liu,Jonathan Liu,Mariya London,Henry Ma,Jessica Mao,Jessica E. McDade,Alexandra McMillan,Aaron M. Moore,Won Chan Oh,Yu Ouyang,Ruchi Patel,Marina Paul,Laura C. Paulsen,Judy Qiu,Alex Rhee,Matthew G. Rubashkin,Ina Y. Soh,Nathaniel E. Sotuyo,Venkatesh Srinivas,Allison Suarez,Andrew D. Wong,Remus S. Wong,Wei Xie,Yijie Xu,Allen T. Yu,Romain Koszul,Romain Koszul,Joel S. Bader,Jef D. Boeke,Srinivasan Chandrasegaran +82 more
TL;DR: SynIII as mentioned in this paper is a designer eukaryotic chromosome based on the S. cerevisiae chromosome III that includes TAG/TAA stop-codon replacements, deletion of subtelomeric regions, introns, transfer RNAs, transposons, and silent mating loci as well as insertion of loxPsym sites.
Journal ArticleDOI
DNA methylation of cord blood cell types: Applications for mixed cell birth studies.
Kelly M. Bakulski,Jason I. Feinberg,Shan V. Andrews,Jack Yang,Shannon Brown,Stephanie McKenney,Frank R. Witter,Jeremy D. Walston,Andrew P. Feinberg,M. Daniele Fallin +9 more
TL;DR: An algorithm is provided for estimating cell proportions in cord blood using the newly developed cord reference panel, which estimates biologically plausiblecell proportions in whole cord blood samples.
Journal ArticleDOI
Association of DNA Methylation Differences With Schizophrenia in an Epigenome-Wide Association Study.
Carolina Montano,Margaret A. Taub,Andrew E. Jaffe,Eirikur Briem,Jason I. Feinberg,Rakel Trygvadottir,Adrian Idrizi,Arni Runarsson,Birna Berndsen,Ruben C. Gur,Tyler M. Moore,Rodney T. Perry,Doug Fugman,Sarven Sabunciyan,Robert H. Yolken,Thomas M. Hyde,Joel E. Kleinman,Janet L. Sobell,Carlos N. Pato,Michele T. Pato,Rodney C.P. Go,Vishwajit L. Nimgaonkar,Daniel R. Weinberger,David L. Braff,David L. Braff,Raquel E. Gur,M. D. Fallin,M. D. Fallin,Andrew P. Feinberg,Andrew P. Feinberg +29 more
TL;DR: This analysis identified 172 replicated new associations with SZ after careful correction for cell type heterogeneity and other potential confounders and found some replicated differentially methylated positions are located in a top-ranked SZ region from genome-wide association study analyses.
Journal ArticleDOI
Paternal sperm DNA methylation associated with early signs of autism risk in an autism-enriched cohort
Jason I. Feinberg,Kelly M. Bakulski,Andrew E. Jaffe,Rakel Tryggvadottir,Shannon Brown,Lynn R. Goldman,Lynn R. Goldman,Lisa A. Croen,Irva Hertz-Picciotto,Craig J. Newschaffer,M. Daniele Fallin,Andrew P. Feinberg +11 more
TL;DR: Data suggest that epigenetic differences in paternal sperm may contribute to autism risk in offspring, and provide evidence that directionally consistent, potentially related epigenetic mechanisms may be operating in the cerebellum of individuals with autism.