J
John A. Ice
Researcher at Oklahoma Medical Research Foundation
Publications - 25
Citations - 1329
John A. Ice is an academic researcher from Oklahoma Medical Research Foundation. The author has contributed to research in topics: Genome-wide association study & Anti-SSA/Ro autoantibodies. The author has an hindex of 13, co-authored 21 publications receiving 1108 citations.
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Journal ArticleDOI
Variants at multiple loci implicated in both innate and adaptive immune responses are associated with Sjogren's syndrome.
Christopher J. Lessard,Christopher J. Lessard,He Li,He Li,Indra Adrianto,John A. Ice,Astrid Rasmussen,Kiely Grundahl,Jennifer A. Kelly,Mikhail G. Dozmorov,Corinne Miceli-Richard,Simon J. Bowman,Susan C. Lester,Per Eriksson,Maija-Leena Eloranta,Johan G. Brun,Lasse G. Gøransson,Erna Harboe,Joel M. Guthridge,Kenneth M. Kaufman,Kenneth M. Kaufman,Marika Kvarnström,Helmi Jazebi,Helmi Jazebi,Deborah S. Cunninghame Graham,Martha E. Grandits,Abu N. M. Nazmul-Hossain,Ketan Patel,Adam Adler,Jacen S. Maier-Moore,Jacen S. Maier-Moore,A. Darise Farris,Michael T. Brennan,James A. Lessard,James Chodosh,Rajaram Gopalakrishnan,Kimberly S. Hefner,Glen D Houston,Andrew J.W. Huang,Pamela J. Hughes,David M Lewis,Lida Radfar,Michael D. Rohrer,Donald U. Stone,Jonathan D. Wren,Timothy J. Vyse,Patrick M. Gaffney,Judith A. James,Judith A. James,Roald Omdal,Marie Wahren-Herlenius,Gabor G. Illei,Torsten Witte,Roland Jonsson,Maureen Rischmueller,Lars Rönnblom,Gunnel Nordmark,Wan-Fai Ng,Xavier Mariette,Juan-Manuel Anaya,Nelson L. Rhodus,Barbara M. Segal,R. Hal Scofield,Courtney G. Montgomery,John B. Harley,John B. Harley,Kathy L. Sivils,Kathy L. Sivils +67 more
TL;DR: The results highlight the importance of genes that are involved in both innate and adaptive immunity in Sjögren's syndrome, including TNFAIP3, PTTG1, PRDM1, DGKQ, FCGR2A, IRAK1BP1, ITSN2 and PHIP, among others.
Journal ArticleDOI
Identification of IRF8, TMEM39A, and IKZF3-ZPBP2 as Susceptibility Loci for Systemic Lupus Erythematosus in a Large-Scale Multiracial Replication Study
Christopher J. Lessard,Christopher J. Lessard,Christopher J. Lessard,Indra Adrianto,John A. Ice,Graham B. Wiley,Jennifer A. Kelly,Stuart B. Glenn,Adam Adler,He Li,He Li,Astrid Rasmussen,Adrienne H. Williams,Julie T. Ziegler,Mary E. Comeau,Miranda C. Marion,Benjamin E. Wakeland,Chaoying Liang,Paula S. Ramos,Kiely Grundahl,Caroline J. Gallant,Graciela S. Alarcón,Juan-Manuel Anaya,Sang Cheol Bae,Susan A. Boackle,Elizabeth E. Brown,Deh Ming Chang,Soo-Kyung Cho,Lindsey A. Criswell,Jeffrey C. Edberg,Barry I. Freedman,Gary S. Gilkeson,Chaim O. Jacob,Judith A. James,Judith A. James,Diane L. Kamen,Robert P. Kimberly,Jae Hoon Kim,Javier Martin,Joan T. Merrill,Timothy B. Niewold,So-Yeon Park,Michelle Petri,Bernardo A. Pons-Estel,Rosalind Ramsey-Goldman,John D. Reveille,R. Hal Scofield,R. Hal Scofield,R. Hal Scofield,Yeong Wook Song,Anne M. Stevens,Anne M. Stevens,Betty P. Tsao,Luis M. Vilá,Timothy J. Vyse,Chack-Yung Yu,Chack-Yung Yu,Joel M. Guthridge,Kenneth M. Kaufman,Kenneth M. Kaufman,Kenneth M. Kaufman,John B. Harley,John B. Harley,Edward K. Wakeland,Carl D. Langefeld,Patrick M. Gaffney,Patrick M. Gaffney,Courtney G. Montgomery,Kathy L. Moser,Kathy L. Moser +69 more
TL;DR: The results of this study increase the number of confirmed SLE risk loci and identify others warranting further investigation, as well as identifying several genes relevant to immunological pathways showed association with SLE.
Journal ArticleDOI
Comparison of the American-European Consensus Group Sjögren's syndrome classification criteria to newly proposed American College of Rheumatology criteria in a large, carefully characterised sicca cohort
Astrid Rasmussen,John A. Ice,He Li,He Li,Kiely Grundahl,Jennifer A. Kelly,Lida Radfar,Donald U. Stone,Kimberly S. Hefner,Juan-Manuel Anaya,Michael D. Rohrer,Rajaram Gopalakrishnan,Glen D Houston,David M Lewis,James Chodosh,John B. Harley,John B. Harley,Pamela J. Hughes,Jacen S. Maier-Moore,Courtney G. Montgomery,Nelson L. Rhodus,A. Darise Farris,Barbara M. Segal,Roland Jonsson,Christopher J. Lessard,Christopher J. Lessard,R. Hal Scofield,Kathy L. Sivils +27 more
TL;DR: It is contention that improvements in diagnostic acumen will require a more fundamental understanding of the pathogenic mechanisms than is at present available and there is no clear evidence for increased value of the new ACR criteria over the old AECG criteria from the clinical or biological perspective.
Journal ArticleDOI
X Chromosome Dose and Sex Bias in Autoimmune Diseases: Increased Prevalence of 47,XXX in Systemic Lupus Erythematosus and Sjögren's Syndrome.
Ke Liu,Biji T. Kurien,Sarah L. Zimmerman,Kenneth M. Kaufman,Diana H. Taft,Leah C. Kottyan,Sara Lazaro,Carrie A. Weaver,John A. Ice,Adam Adler,James Chodosh,Lida Radfar,Astrid Rasmussen,Donald U. Stone,David M Lewis,Shibo Li,Kristi A. Koelsch,Ann Igoe,Mitali Talsania,Jay Kumar,Jacen S. Maier-Moore,Valerie M. Harris,Rajaram Gopalakrishnan,Roland Jonsson,James A. Lessard,Xianglan Lu,Jacques-Eric Gottenberg,Juan-Manuel Anaya,Deborah S. Cunninghame-Graham,Andrew J.W. Huang,Michael T. Brennan,Pamela J. Hughes,Gabor G. Illei,Corinne Miceli-Richard,Edward C. Keystone,Vivian P. Bykerk,Gideon M. Hirschfield,Gang Xie,Wan-Fai Ng,Gunnel Nordmark,Per Eriksson,Roald Omdal,Nelson L. Rhodus,Maureen Rischmueller,Michael D. Rohrer,Barbara M. Segal,Timothy J. Vyse,Marie Wahren-Herlenius,Torsten Witte,Bernardo A. Pons-Estel,Marta E. Alarcón-Riquelme,Joel M. Guthridge,Judith A. James,Christopher J. Lessard,Jennifer A. Kelly,Susan D. Thompson,Patrick M. Gaffney,Courtney G. Montgomery,Jeffrey C. Edberg,Robert P. Kimberly,Graciela S. Alarcón,C. Langefeld,Gary S. Gilkeson,Diane L. Kamen,Betty P. Tsao,W. Joseph McCune,Jane E. Salmon,Joan T. Merrill,Michael H. Weisman,Daniel J. Wallace,Tammy O. Utset,Erwin P. Bottinger,Christopher I. Amos,Katherine A. Siminovitch,Xavier Mariette,Kathy L. Sivils,John B. Harley,R. Hal Scofield +77 more
TL;DR: In this article, the authors found that trisomy X (47,XXX; occurring in ∼ 1 in 1,000 live female births) would be increased in patients with female-predominant diseases (systemic lupus erythematosus [SLE], primary Sjogren's syndrome [SS], primary biliary cirrhosis, and rheumatoid arthritis [RA]) compared to patients with diseases without female predominance (sarcoidosis) and compared to controls.
Journal ArticleDOI
Identification of a Systemic Lupus Erythematosus Risk Locus Spanning ATG16L2, FCHSD2, and P2RY2 in Koreans
Christopher J. Lessard,Satria Sajuthi,Jian Zhao,Kwangwoo Kim,John A. Ice,He Li,Hannah C. Ainsworth,Astrid Rasmussen,Jennifer A. Kelly,Miranda C. Marion,So Young Bang,Young Bin Joo,Jeongim Choi,Hye Soon Lee,Young Mo Kang,Chang Hee Suh,Won Tae Chung,Soo Kon Lee,Jung Yoon Choe,Seung Cheol Shim,Ji Hee Oh,Young-Jin Kim,Bok Ghee Han,Nan Shen,Hwee Siew Howe,Edward K. Wakeland,Quan Zhen Li,Yeong Wook Song,Patrick M. Gaffney,Marta E. Alarcón-Riquelme,Lindsey A. Criswell,Chaim O. Jacob,Robert P. Kimberly,Timothy J. Vyse,John B. Harley,Kathy L. Sivils,Sang Cheol Bae,Carl D. Langefeld,Betty P. Tsao +38 more
TL;DR: Using an unbiased genome‐wide association scan and replication analysis, it is sought to identify the genetic loci associated with SLE in a Korean population.