J
John G. Gums
Researcher at University of Florida
Publications - 165
Citations - 4000
John G. Gums is an academic researcher from University of Florida. The author has contributed to research in topics: Hydrochlorothiazide & Atenolol. The author has an hindex of 31, co-authored 160 publications receiving 3551 citations. Previous affiliations of John G. Gums include East Tennessee State University & American Association of Colleges of Pharmacy.
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Journal ArticleDOI
Large-Scale Gene-Centric Meta-analysis across 32 Studies Identifies Multiple Lipid Loci
Folkert W. Asselbergs,Yiran Guo,Yiran Guo,Erik P A Van Iperen,Suthesh Sivapalaratnam,Vinicius Tragante,Matthew B. Lanktree,Leslie A. Lange,Berta Almoguera,Yolande Appelman,John Barnard,Jens Baumert,Amber L. Beitelshees,Tushar Bhangale,Yii-Der Ida Chen,Tom R. Gaunt,Yan Gong,Jemma C. Hopewell,Toby Johnson,Marcus E. Kleber,Taimour Y. Langaee,Mingyao Li,Yun Li,Kiang Liu,Caitrin W. McDonough,Matthijs F.L. Meijs,Rita P.S. Middelberg,Kiran Musunuru,Kiran Musunuru,Christopher P. Nelson,Jeffery R. O'Connell,Sandosh Padmanabhan,James S. Pankow,Nathan Pankratz,Suzanne Rafelt,Ramakrishnan Rajagopalan,Simon P. R. Romaine,Nicholas J. Schork,Jonathan A. Shaffer,Haiqing Shen,Erin N. Smith,Sam E. Tischfield,Peter J. van der Most,Jana V. van Vliet-Ostaptchouk,Niek Verweij,Kelly A. Volcik,Li Zhang,Kent R. Bailey,Kristian M. Bailey,Florianne Bauer,Jolanda M. A. Boer,Peter S. Braund,Amber A. Burt,Paul Burton,Sarah G. Buxbaum,Wei Chen,Rhonda M. Cooper-DeHoff,L. Adrienne Cupples,L. Adrienne Cupples,Jonas S. Dejong,Christian Delles,David Duggan,Myriam Fornage,Clement E. Furlong,Nicole L. Glazer,John G. Gums,Claire E. Hastie,Michael V. Holmes,Thomas Illig,Susan Kirkland,Mika Kivimäki,Ronald Klein,Barbara E.K. Klein,Charles Kooperberg,Kandice Kottke-Marchant,Meena Kumari,Andrea Z. LaCroix,Laya Mallela,Gurunathan Murugesan,Jose M. Ordovas,Willem H. Ouwehand,Wendy S. Post,Richa Saxena,Richa Saxena,Hubert Scharnagl,Pamela J. Schreiner,Tina Shah,Denis C. Shields,Daichi Shimbo,Sathanur R. Srinivasan,Ronald P. Stolk,Daniel I. Swerdlow,Herman A. Taylor,Eric J. Topol,Elina Toskala,Joost L. Van Pelt,Jessica van Setten,Salim Yusuf,John C. Whittaker,John C. Whittaker,A. H. Zwinderman,Sonia S. Anand,Anthony J. Balmforth,Gerald S. Berenson,Connie R. Bezzina,Connie R. Bezzina,Bernhard O. Boehm,Eric Boerwinkle,Juan P. Casas,Juan P. Casas,Mark J. Caulfield,Robert Clarke,John M. C. Connell,Karen J. Cruickshanks,Karina W. Davidson,Ian N. M. Day,Paul I.W. de Bakker,Paul I.W. de Bakker,Paul I.W. de Bakker,Pieter A. Doevendans,Anna F. Dominiczak,Alistair S. Hall,Catharina A. Hartman,Christian Hengstenberg,Hans L. Hillege,Marten H. Hofker,Steve E. Humphries,Gail P. Jarvik,Julie A. Johnson,Bernhard M. Kaess,Sekar Kathiresan,Sekar Kathiresan,Wolfgang Koenig,Debbie A Lawlor,Winfried März,Winfried März,Olle Melander,Braxton D. Mitchell,Grant W. Montgomery,Patricia B. Munroe,Sarah S. Murray,Stephen Newhouse,N. Charlotte Onland-Moret,Neil R Poulter,Bruce M. Psaty,Bruce M. Psaty,Susan Redline,Stephen S. Rich,Jerome I. Rotter,Heribert Schunkert,Peter Sever,Alan R. Shuldiner,Alan R. Shuldiner,Roy L. Silverstein,Alice V. Stanton,Alice V. Stanton,Barbara Thorand,Mieke D. Trip,Michael Y. Tsai,Pim van der Harst,Ellen Van Der Schoot,Yvonne T. van der Schouw,W. M. Monique Verschuren,Hugh Watkins,Arthur A.M. Wilde,Bruce H. R. Wolffenbuttel,John Whitfield,G. Kees Hovingh,Christie M. Ballantyne,Cisca Wijmenga,Muredach P. Reilly,Nicholas G. Martin,James G. Wilson,Daniel J. Rader,Nilesh J. Samani,Nilesh J. Samani,Alexander P. Reiner,Robert A. Hegele,John J.P. Kastelein,Aroon D. Hingorani,Philippa J. Talmud,Hakon Hakonarson,Clara C. Elbers,Brendan J. Keating,Fotios Drenos +184 more
TL;DR: This large meta-analysis of lipid phenotypes with the use of a dense gene-centric approach identified multiple SNPs not previously described in established lipid genes and several previously unknown loci, suggesting that a focused genotyping approach can further increase the understanding of heritability of plasma lipids.
Journal ArticleDOI
Gene-centric Meta-analysis in 87,736 Individuals of European Ancestry Identifies Multiple Blood-Pressure-Related Loci
Vinicius Tragante,Michael R. Barnes,Santhi K. Ganesh,Matthew B. Lanktree,Wei Guo,Nora Franceschini,Erin N. Smith,Toby Johnson,Michael V. Holmes,Sandosh Padmanabhan,Konrad J. Karczewski,Berta Almoguera,John Barnard,Jens Baumert,Yen Pei C. Chang,Clara C. Elbers,Martin Farrall,Mary E. Fischer,Tom R. Gaunt,Johannes M.I.H. Gho,Christian Gieger,Anuj Goel,Yan Gong,Aaron Isaacs,Marcus E. Kleber,Irene Mateo Leach,Caitrin W. McDonough,Matthijs F.L. Meijs,Olle Melander,Christopher P. Nelson,Christopher P. Nelson,Ilja M. Nolte,Nathan Pankratz,Thomas S. Price,Jonathan A. Shaffer,Sonia Shah,Maciej Tomaszewski,Peter J. van der Most,Erik P A Van Iperen,Judith M. Vonk,Kate Witkowska,Caroline O. L. Wong,Li Zhang,Amber L. Beitelshees,Gerald S. Berenson,Deepak L. Bhatt,Morris Brown,Amber A. Burt,Rhonda M. Cooper-DeHoff,John M. C. Connell,Karen J. Cruickshanks,Sean P. Curtis,George Davey-Smith,Christian Delles,Ron T. Gansevoort,Xiuqing Guo,Shen Haiqing,Claire E. Hastie,Marten H. Hofker,Marten H. Hofker,G. Kees Hovingh,Daniel Seung Kim,Susan Kirkland,Barbara E.K. Klein,Ronald Klein,Yun Li,Steffi Maiwald,Christopher Newton-Cheh,Eoin O'Brien,N. Charlotte Onland-Moret,Walter Palmas,Afshin Parsa,Brenda W.J.H. Penninx,Mary Pettinger,Ramachandran S. Vasan,Jane E. Ranchalis,Paul M. Ridker,Lynda M. Rose,Peter S. Sever,Daichi Shimbo,Laura Steele,Ronald P. Stolk,Barbara Thorand,Mieke D. Trip,Cornelia M. van Duijn,W M Monique Verschuren,Cisca Wijmenga,Sharon B. Wyatt,J. Hunter Young,Aeilko H. Zwinderman,Connie R. Bezzina,Eric Boerwinkle,Juan P. Casas,Mark J. Caulfield,Aravinda Chakravarti,Daniel I. Chasman,Karina W. Davidson,Pieter A. Doevendans,Anna F. Dominiczak,Garret A. FitzGerald,John G. Gums,Myriam Fornage,Hakon Hakonarson,Indrani Halder,Hans L. Hillege,Thomas Illig,Gail P. Jarvik,Julie A. Johnson,John J.P. Kastelein,Wolfgang Koenig,Meena Kumari,Winfried März,Sarah S. Murray,Jeffrey R. O'Connell,Albertine J. Oldehinkel,James S. Pankow,Daniel J. Rader,Susan Redline,Muredach P. Reilly,Eric E. Schadt,Kandice Kottke-Marchant,Harold Snieder,Michael Snyder,Alice Stanton,Martin D. Tobin,André G. Uitterlinden,Pim van der Harst,Yvonne T. van der Schouw,Nilesh J. Samani,Nilesh J. Samani,Hugh Watkins,Andrew D. Johnson,Alexander P. Reiner,Xiaofeng Zhu,Paul I.W. de Bakker,Daniel Levy,Folkert W. Asselbergs,Folkert W. Asselbergs,Patricia B. Munroe,Brendan J. Keating +139 more
TL;DR: The findings extend the understanding of genes involved in BP regulation, which may provide new targets for therapeutic intervention or drug response stratification and provide support for a putative role in hypertension of several genes.
Journal ArticleDOI
Outcome Analysis of a Pharmacist-Managed Anticoagulation Service
TL;DR: A pharmacist‐managed AMS in a family practice setting can result in improved outcomes for patients receiving warfarin and is cost effective in treating and preventing thromboembolic disorders.
Journal ArticleDOI
Loci influencing blood pressure identified using a cardiovascular gene-centric array
Santhi K. Ganesh,Vinicius Tragante,Wei Guo,Yiran Guo,Matthew B. Lanktree,Erin N. Smith,Toby Johnson,Berta Almoguera Castillo,John Barnard,Jens Baumert,Yen Pei C. Chang,Clara C. Elbers,Martin Farrall,Mary E. Fischer,Nora Franceschini,Tom R. Gaunt,Johannes M.I.H. Gho,Christian Gieger,Yan Gong,Aaron Isaacs,Marcus E. Kleber,Irene Mateo Leach,Caitrin W. McDonough,Matthijs F.L. Meijs,Olle Mellander,Cliona Molony,Ilja M. Nolte,Sandosh Padmanabhan,Tom S. Price,Ramakrishnan Rajagopalan,Jonathan A. Shaffer,Sonia Shah,Haiqing Shen,Nicole Soranzo,Peter J. van der Most,Erik P A Van Iperen,Jessica van Setten,Judith M. Vonk,Li Zhang,Amber L. Beitelshees,Gerald S. Berenson,Deepak L. Bhatt,Jolanda M. A. Boer,Eric Boerwinkle,Ben Burkley,Amber A. Burt,Aravinda Chakravarti,Wei Chen,Rhonda M. Cooper-DeHoff,Sean P. Curtis,Albert W. Dreisbach,David Duggan,Georg Ehret,Richard R. Fabsitz,Myriam Fornage,Ervin R. Fox,Clement E. Furlong,Ron T. Gansevoort,Marten H. Hofker,G. Kees Hovingh,Susan Kirkland,Kandice Kottke-Marchant,Abdullah Kutlar,Andrea Z. LaCroix,Taimour Y. Langaee,Yun Li,Honghuang Lin,Kiang Liu,Steffi Maiwald,Rainer Malik,Gurunathan Murugesan,Christopher Newton-Cheh,Christopher Newton-Cheh,Jeffery R. O'Connell,N. Charlotte Onland-Moret,Willem H. Ouwehand,Walter Palmas,Brenda W.J.H. Penninx,Carl J. Pepine,Mary Pettinger,Joseph F. Polak,Vasan S. Ramachandran,Vasan S. Ramachandran,Jane E. Ranchalis,Susan Redline,Paul M. Ridker,Lynda M. Rose,Hubert Scharnag,Hubert Scharnag,Nicholas J. Schork,Daichi Shimbo,Alan R. Shuldiner,Alan R. Shuldiner,Sathanur R. Srinivasan,Ronald P. Stolk,Herman A. Taylor,Barbara Thorand,Mieke D. Trip,Cornelia M. van Duijn,W. M. Monique Verschuren,Cisca Wijmenga,Bernhard R. Winkelmann,Sharon B. Wyatt,J. Hunter Young,Bernhard O. Boehm,Mark J. Caulfield,Daniel I. Chasman,Karina W. Davidson,Pieter A. Doevendans,Garret A. FitzGerald,John G. Gums,Hakon Hakonarson,Hans L. Hillege,Thomas Illig,Gail P. Jarvik,Julie A. Johnson,John J.P. Kastelein,Wolfgang Koenig,Winfried März,Winfried März,Braxton D. Mitchell,Sarah S. Murray,Albertine J. Oldehinkel,Daniel J. Rader,Muredach P. Reilly,Alexander P. Reiner,Eric E. Schadt,Roy L. Silverstein,Roy L. Silverstein,Harold Snieder,Alice Stanton,André G. Uitterlinden,Pim van der Harst,Yvonne T. van der Schouw,Nilesh J. Samani,Nilesh J. Samani,Andrew D. Johnson,Patricia B. Munroe,Paul I.W. de Bakker,Paul I.W. de Bakker,Paul I.W. de Bakker,Xiaofeng Zhu,Daniel Levy,Brendan J. Keating,Folkert W. Asselbergs +144 more
TL;DR: Two novel loci associated with BP are identified and multiple previously reported associations are confirmed, extending the understanding of genes involved in BP regulation and some of which may eventually provide new targets for therapeutic intervention.
Journal ArticleDOI
Pharmacogenomics of antihypertensive drugs: Rationale and design of the Pharmacogenomic Evaluation of Antihypertensive Responses (PEAR) study
Julie A. Johnson,Eric Boerwinkle,Issam Zineh,Arlene B. Chapman,Kent R. Bailey,Rhonda M. Cooper-DeHoff,John G. Gums,R. Whit Curry,Yan Gong,Amber L. Beitelshees,Gary L. Schwartz,Stephen T. Turner +11 more
TL;DR: This trial is to identify the genetic determinants of the antihypertensive and adverse metabolic responses to a thiazide diuretic, a beta-blocker, and their combination through candidate gene and genome-wide association approaches.