John M. Pezzuto

TL;DR: A chemically diverse group of compounds was included in the evaluation, such as flavonoids, retinoids, isothiocyanates, sulfur-containing compounds and phenolic antioxidant compounds, and showed potent inhibitory effects in this process to understand the cancer chemopreventive potential mediated by these substances.

TL;DR: Observations generalize the concept that estrous cycle stage at the time of NMU injection alters subsequent mammary carcinoma biology, and represents the first experimental evidence that slower growing and responding estrogen receptor positive rat Mammary carcinomas may be associated with an increase in circulating estrogen prior to carcinogen exposure.

TL;DR: Results indicate that compound 5 acts as a cytotoxic agent via a novel mechanism, but this substance was inactive in in vivo evaluations using the murine lung carcinoma and human colon carcinoma models.

TL;DR: In this paper, the proton and carbon spectra for pseudolaric acid B (1) were assigned using a combination of one-and two-dimensional NMR spectroscopic techniques.